World Journal of Psychiatry

Near-infrared spectroscopy in schizophrenia: A bibliometric perspective
Fei XX, Wang SQ, Li JY, Xu ZY, Wang JX, Gao YQ and Hu Y
Compared with current methods used to assess schizophrenia, near-infrared spectroscopy (NIRS) has the advantages of providing noninvasive and real-time monitoring of functional activities of the brain and providing direct and objective assessment information.
Family functioning mediation in tic severity and quality of life for children with Tourette syndrome
Hu SJ, Li Y, Yang QH, Yang K, Jun JH, Cui YH and Lei TY
Tourette syndrome (TS) is recognized as a neurodevelopmental disorder profoundly influenced by familial factors, particularly family functioning. However, the relationship among family functioning, tic severity, and quality of life in individuals with TS during childhood and adolescence remains unclear. We hypothesized that family functioning plays a role in the association between the severity of TS and quality of life in children.
Who can benefit more from its twelve-week treatment: A prospective cohort study of blonanserin for patients with schizophrenia
Xu BY, Jin K, Wu HS, Liu XJ, Wang XJ, Sang H, Li KQ, Sun MJ, Meng HQ, Deng HL, Xun ZY, Yang XD, Zhang L, Li GJ, Zhang RL, Cai DF, Liu JH, Zhao GJ, Liu LF, Wang G, Zhao CL, Guo B, Jin SC, Huang LY, Yang FD, Zheng JM, Zhan GL, Fang MS, Meng XJ, Zhang GY, Li HM, Liu XL, Li JH, Wu B, Li HY and Chen JD
Blonanserin (BNS) is a well-tolerated and effective drug for treating schizophrenia.
Association between intercellular adhesion molecule-1 to depression and blood-brain barrier penetration in cerebellar vascular disease
Chen JL, Wang R, Ma PQ, Wang YM and Tang QQ
Cerebral small vessel disease (CSVD) is a prevalent cerebrovascular disease in clinical practice that is often associated with macrovascular disease. A clear understanding of the underlying causes of CSVD remains elusive.
Holistic approaches to mitigating psychological distress in gynecological cancer patients
Byeon H
This article delves into the psychological impact of gynecological malignancies and suggests pathways to improve the quality of life (QoL) for affected patients. Building on Shang 's comprehensive analysis, this piece integrates insights from various studies to highlight the profound influence of psychological and physical symptoms on patients undergoing treatment for gynecological cancers. The study underscores that anxiety and depression significantly exacerbate the disease's toll. Factors such as physical exercise and digital and interactive health interventions show promise in mitigating these adverse effects. The article emphasizes the necessity for a holistic care approach that addresses both physical and emotional needs. Recommendations include enhanced training for healthcare providers, public awareness campaigns, streamlined diagnostic pathways, and improved access to specialist care. These integrated strategies aim to ensure that women facing gynecological cancers can maintain an optimal QoL through comprehensive and multidisciplinary care models.
Major depressive disorder is associated with mitochondrial T14502C mutation in two Han Chinese families
Jing P, Yu HH, Wu TT, Yu BH, Liang M, Xia TT, Xu XW, Xu T, Liu LJ and Zhang XB
Globally, the World Health Organization ranks major depressive disorder (MDD) as the leading cause of disability. However, MDD molecular etiology is still poorly understood.
Enhancing adolescent mental health through cognitive and social support: Insights from study on depression in Chinese adolescents
Okpete UE and Byeon H
Adolescent depression is a growing global health concern, affecting 14% of adolescents and leading to severe consequences such as academic failure, substance abuse, and suicidal ideation. The study by Yu , investigates the cognitive and social factors influencing depression in 795 Chinese adolescents. Findings reveal that negative life events (NLEs) and dysfunctional attitudes are strongly associated with depressive symptoms, while social support moderates the impact of NLEs but not dysfunctional attitudes. The study highlights the need for cognitive-behavioural interventions targeting perfectionism and autonomy, and the importance of strengthening social support systems in schools and communities. Culturally sensitive, holistic approaches to adolescent mental health are crucial for addressing both the internal vulnerabilities and external pressures contributing to depression. Further research is needed to explore the roles of peer and parental support and the long-term effects of these factors across diverse cultural contexts.
Dysfunctional attitudes, social support, negative life events, and depressive symptoms in Chinese adolescents: A moderated mediation model
Yu TF, Liu L, Shang LN, Xu FF, Chen ZM and Qian LJ
Depression is a prevalent psychological issue in adolescents that is significantly related to negative life events (NLEs) and dysfunctional attitudes. High levels of social support can significantly buffer NLEs' effect on depression. Currently, there is limited research on how social support moderates the relationship between NLEs, dysfunctional attitudes, and depression in adolescents in China. It is imperative to investigate this moderating effect to mitigate dysfunctional attitudes in adolescent undergoing depressive mood, ultimately enhancing their overall mental health.
Study on the correlation between abdominal infection and psychological stress in children based on nucleic acid detection
Wang GB, Zhang XF, Liang B, Lei J and Xue J
Diagnosing and treating abdominal infection in children remains a challenge. Nucleic acid detection, as a rapid and accurate diagnosis tool, has great significance in this field.
Unraveling the complexities of adolescent depression: A call for action
Zhang Y, Hei MY, Wang MZ, Zhang JG and Wang S
The adolescent years are a period of profound change, both physically and psychologically. For many, these years are marked by excitement and exploration, but for others, they are fraught with challenges that can lead to significant mental health issues. Depression, in particular, has become an increasingly prevalent concern among adolescents worldwide, and its multifaceted etiology requires a comprehensive approach to understanding and intervention. A recent study on the relationships among negative life events, dysfunctional attitudes, social support, and depressive symptoms in Chinese adolescents offers valuable insights into the complex interplay between various factors contributing to adolescent depression. The authors explore a moderated mediation model to better understand how these factors interact with and contribute to the onset of depression. This article aims to delve into the key findings of the study, highlight its implications for clinical practice, and encourage further research in this critical area.
Examination of emotional distress, depression, and anxiety in neurodiverse students: A cross-sectional study
Otu MS and Sefotho MM
Neurodiverse students frequently encounter distinct challenges that can adversely affect their mental well-being. This research aimed to investigate emotional distress, depression, and anxiety among neurodiverse students, examine the interrelationships among these factors, and assess the impact of participant characteristics.
Correlation linking illness perception, negative emotions, and the post-operative recovery effect in patients with perianal disease
Hou SX, Dai FJ, Wang XX, Wang SW and Tian T
Improvements in the standard of living have led to increased attention to perianal disease. Although surgical treatments are effective, the outcomes of post-operative recovery (POR) are influenced by various factors, including individual differences among patients, the characteristics of the disease itself, and the psychological state of the patient. Understanding these factors can help healthcare providers develop more personalized and effective post-operative care plans for patients with perianal disease.
Repetitive transcranial magnetic stimulation enhanced by neuronavigation in the treatment of depressive disorder and schizophrenia
Wang XY, Zhang YB, Mu RX, Cui LB and Wang HN
This editorial assesses the advancements in neuronavigation enhanced repetitive transcranial magnetic stimulation for depressive disorder and schizophrenia treatment. Conventional repetitive transcranial magnetic stimulation faces challenges due to the intricacies of brain anatomy and patient variability. Neuronavigation offers innovative solutions by integrating neuroimaging with three-dimensional localization to pinpoint brain regions and refine therapeutic targeting. This systematic review of recent literature underscores the enhanced efficacy of neuronavigation in improving treatment outcomes for these disorders. This editorial highlights the pivotal role of neuronavigation in advancing psychiatric care.
Resting-state functional magnetic resonance imaging and support vector machines for the diagnosis of major depressive disorder in adolescents
Yu ZH, Yu RQ, Wang XY, Ren WY, Zhang XQ, Wu W, Li X, Dai LQ and Lv YL
Research has found that the amygdala plays a significant role in underlying pathology of major depressive disorder (MDD). However, few studies have explored machine learning-assisted diagnostic biomarkers based on amygdala functional connectivity (FC).
Narrative nursing for negative emotions in patients with acute pancreatitis: Based on model construction and application
Zhou LJ, Wu J, Huang WJ, Shen AW, Yin YP, Sun HL and Yuan YT
Acute pancreatitis (AP), as a common acute abdomen disease, has a high incidence rate worldwide and is often accompanied by severe complications. Negative emotions lead to increased secretion of stress hormones, elevated blood sugar levels, and enhanced insulin resistance, which in turn increases the risk of AP and significantly affects the patient's quality of life. Therefore, exploring the intervention effects of narrative nursing programs on the negative emotions of patients with AP is not only helpful in alleviating psychological stress and improving quality of life but also has significant implications for improving disease outcomes and prognosis.
Progress of systematic psychological interventions in elderly patients with femoral fractures: A comprehensive review
Li J, Hu J and Zhang Q
This review aims to gain a deeper understanding of the psychological state of elderly patients with femoral fractures and provide more theoretical and practical support for clinical treatment and care. Through a literature analysis, we found that elderly patients with femoral fractures face various psychological issues such as anxiety, depression, sleep disorders, and social isolation. The application of systematic nursing interventions in clinical practice, including cognitive-behavioral therapy, mindfulness therapy, family therapy, art therapy, interpersonal therapy, emotion-focused therapy, and relaxation training, has yielded significant results. Systematic psychological interventions can improve the psychological state and quality of life of elderly patients with femoral fractures. Therefore, promoting the application and practice of systematic psychological interventions in the clinical care of elderly patients with fractures will provide more effective psychological services to a wider group of patients with fractures in the future.
Correlation among anxiety and depression, fear of disease progression, and social support in coronary heart disease
Xu Y, Ma HX, Liu SS and Gong Q
The mental well-being of individuals with coronary heart disease (CHD) during the intensive care unit (ICU) transition period is a multifaceted and significant concern. In this phase, the individuals might encounter psychological challenges like anxiety and depression, which can impede their recuperation and potentially have lasting effects on their health.
Application of proton magnetic resonance spectroscopy in metabolic alterations of prefrontal white and gray matter in depression adolescents
Zou Y, Wu YQ, Han YJ, He XM and Zhao J
Cases of depression among adolescents are gradually increasing. The study of the physiological basis of cognitive function from a biochemical perspective has therefore been garnering increasing attention. Depression has been hypothesized to be associated with the brain biochemical metabolism of the anterior cingulate gyrus, frontal lobe white matter, and the thalamus.
Research progress on the mechanism of exercise against depression
Zhao YL, Sun SY, Qin HC, Zhu YL, Luo ZW, Qian Y and Chen S
The substantial global health burden of depression encourages the development of innovative and broadly effective interventions. This paper aimed to examine recent advancements by which exercise works as an antidepressant and recommends optimal types and quantity of exercise as supplemental therapies in treating depression. Sedentary behavior and low physical activity significantly influence the onset of depression. Being an effective treatment option, exercise can significantly reduce depression risk. Exercise exerts antidepressant effects as it modulates neurotransmitters, neuroplasticity, the immune system, and hormone levels. Effective exercise forms include yoga, strength training, and walking/jogging. Tailored exercise regimens that consider individual preferences and tolerability can improve outcomes. Regular exercise enhances general well-being and reduces depressive symptoms. Additional research is needed to understand the complex basis of exercise's effects on depression. Exercise is a cost-effective and accessible intervention for depression management that needs additional exploration. Thus, customized exercise programs, as per each patient's needs, are essential for their successful implementation clinically.
Interoception mediates the association between social support and sociability in patients with major depressive disorder
Wang WL, Liu JK, Sun YF, Liu XH, Ma YH, Gao XZ, Chen LM, Zhou ZH and Zhou HL
Interoception dysfunction has an important impact on the onset and development of major depressive disorder (MDD). Social support serves as a protective factor against MDD, and sociability also plays a significant role in this condition. These interconnected constructs-social support and sociability-play pivotal roles in MDD. However, no research on the mechanisms underlying the associations between social support and sociability, particularly the potential role of interoception, have been reported.
Large multimodal models assist in psychiatry disorders prevention and diagnosis of students
Liu XQ, Wang X and Zhang HR
Students are considered one of the groups most affected by psychological problems. Given the highly dangerous nature of mental illnesses and the increasingly serious state of global mental health, it is imperative for us to explore new methods and approaches concerning the prevention and treatment of mental illnesses. Large multimodal models (LMMs), as the most advanced artificial intelligence models ( ChatGPT-4), have brought new hope to the accurate prevention, diagnosis, and treatment of psychiatric disorders. The assistance of these models in the promotion of mental health is critical, as the latter necessitates a strong foundation of medical knowledge and professional skills, emotional support, stigma mitigation, the encouragement of more honest patient self-disclosure, reduced health care costs, improved medical efficiency, and greater mental health service coverage. However, these models must address challenges related to health, safety, hallucinations, and ethics simultaneously. In the future, we should address these challenges by developing relevant usage manuals, accountability rules, and legal regulations; implementing a human-centered approach; and intelligently upgrading LMMs through the deep optimization of such models, their algorithms, and other means. This effort will thus substantially contribute not only to the maintenance of students' health but also to the achievement of global sustainable development goals.
Brain networks in newborns and infants with and without sensorineural hearing loss: A functional near-infrared spectroscopy study
Tan J, Hou QM, Zhang F, Duan X, Zhang YL, Lee YJ and Yan H
Understanding the impact of early sensory deficits on brain development is essential for understanding developmental processes and developing potential interventions. While previous studies have looked into the impact of prenatal experiences on language development, there is a lack of research on how these experiences affect early language and brain function development in individuals with sensorineural hearing loss (SNHL).
Clinical, scientific and stakeholders' caring about identity perturbations
Löffler-Stastka H
In this editorial we comment on the article by Zhang published in the recent issue of the . We focus on identity diffusion, identity perturbations, their origin and developmental pathways. This is an upcoming problem in the society as not only school children are affected. Adolescents and young people suffer from uncertainty in gender identity, in self-image, migration effects due to chronic crises caused by war, pandemic disruptions or climate change. We show how such chronic uncertainty can be cared for, treated, and contained. The key is affective holding, reflection and to provide adequate affective mentalizing in a close concomitant way. These key features also depend on ambient conditions, such as psychotherapeutic care. In a qualitative interview study carried out in a cyclical research design with a comparative analysis on the basis of thematic coding using Grounded Theory Methodology we found institutionalized defenses in health policies. Professionals request better training and adequat academic knowledge as well as research into unresolved areas for improvement of the ambient conditions for adequat development of the self. Practice points for further clinical and scientific development are given and discussed.
Influence of the continuing COVID-19 epidemic on sleep quality and psychological status of healthcare workers in private institutions
Ho MI, Wu ZH, Chen YY, Leong WI, Wang J, Zhou H, Wu ZT, Mao YQ, Du JA, Zheng Y, Yu Y, Do Lago Comandante P, Yu LL and Wu QB
On January 22, 2020, Macao reported its first case of coronavirus disease 2019 (COVID-19) infection. By August 2021, the situation had escalated into a crisis of community transmission. In response, the government launched a recruitment campaign seeking assistance and services of healthcare workers (HCWs) from the private sector throughout Macao. These participants faced concerns about their own health and that of their families, as well as the responsibility of maintaining public health and wellness. This study aims to determine whether the ongoing epidemic has caused them physical and psychological distress.
Analysis of risk factors for postpartum depression after cesarean section in women with early-onset preeclampsia
Wang R, Liang X and Su XY
Early-onset preeclampsia significantly increases maternal and fetal morbidity and mortality. Many pregnant women with early onset preeclampsia choose cesarean section as their delivery method. Although extensive research has explored the association between postpartum depression (PPD) and cesarean section, few studies have investigated the risk factors after cesarean section in women with early-onset preeclampsia.
Bidirectional relationship between diabetes mellitus and depression: Mechanisms and epidemiology
Liu Y, Huang SY, Liu DL, Zeng XX, Pan XR and Peng J
Diabetes mellitus and depression exhibit a complex bidirectional relationship that profoundly impacts patient health and quality of life. This review explores the physiological mechanisms, including inflammation, oxidative stress, and neuroendocrine dysregulation, that link these conditions. Psychosocial factors such as social support and lifestyle choices also contribute significantly. Epidemiological insights reveal a higher prevalence of depression among diabetics and an increased risk of diabetes in depressed individuals, influenced by demographic variables. Integrated management strategies combining mental health assessments and personalized treatments are essential. Future research should focus on longitudinal and multi-omics studies to deepen understanding and improve therapeutic outcomes.
Association between gene C-1019G polymorphism and antidepressant response in patients with major depressive disorder: A meta-analysis
Wu HN, Zhu SY, Zhang LN, Shen BH and Xu LL
Major depressive disorder (MDD) is a substantial global health concern, and its treatment is complicated by the variability in individual response to antidepressants.
Tree: Reducing the use of restrictive practices on psychiatric wards through virtual reality immersive technology training
Phiri P, Pemberton L, Liu Y, Yang X, Salmon J, Boulter I, Sajid S, Clarke J, McMillan A, Shi JQ and Delanerolle G
Restrictive practices (RPs) are defined by measures linked to physical and chemical restraints to reduce the movement or control behaviours during any emergency. Seclusion is an equal part of RPs intended to isolate and reduce the sensory stimulation to safeguard the patient and those within the vicinity. Using interventions by way of virtual reality (VR) could assist with reducing the need for RPs as it could help reduce anxiety or agitation by way of placing users into realistic and immersive environments. This could also aid staff to and change current RPs.
Effects of positive psychological control intervention on sleep and psychology of officers and soldiers working at sea
Liu YQ, Sun JL, Jing M, Liu GX, Shi J, Zhu XW, Wang F and Ye MH
The working environment of submarine crews is also very special. They are in a closed, high-temperature, high-noise, high-vibration and narrow working and living space for a long time, and they suffer from physical discomfort caused by seasickness, which will affect the mental health of officers and soldiers. American psychologists have achieved positive results in psychological resilience training for officers and soldiers from the perspective of positive psychology. At present, there are few reports on the correlation between psychological resilience in the field of domestic research on submarine crew psychology, and it is necessary to conduct further research.
Psychological stress impact neurotrophic factor levels in patients with androgenetic alopecia and correlated with disease progression
Cheng Y, Lv LJ, Cui Y, Han XM, Zhang Y and Hu CX
Androgenetic alopecia (AGA) is a common form of hair loss that can be influenced by psychological factors.