To determine the effects of rapid (1 minute) and slow (10 minutes) intravenous (IV) injection of sodium penicillin on arterial blood pressure in anesthetized horses.

Burn-related neuropathic pain (BRNP) can arise following burn-induced nerve damage, affects approximately 6% of burned human patients and can result in chronic pain. Although widely studied in humans, data on BRNP or its treatment in animals is lacking. A 4-year-old domestic shorthair cat was presented with an infected, non-healing wound suspected to be a caustic burn. Initial treatments included surgical debridement, antimicrobials, and corticosteroids, but the cat developed persistent pruritus leading to self-inflicted trauma. Despite various interventions, including prednisone, chloramphenicol and cyclosporine, clinical signs persisted, leading to a referral for suspected BRNP. Additional support for neuropathic pain was provided through thermal sensitivity testing and applying a modified Neuropathic Pain Symptoms Inventory. Treatment with gabapentin, amantadine, and acupuncture yielded little improvement, prompting an increasing escalation in gabapentin dosage. The cat was then treated with gabapentin compounded with compound 194, a small molecule that is a potent and selective inhibitor of voltage-gated sodium channel 1.7 (Na1.7). The cat exhibited significant pain relief and improvements in overall condition. After gabapentin was tapered, compound 194 effectively maintained pain control. The cat's clinical condition stabilized with no adverse effects. Hematology and serum biochemistry results remained within reference intervals throughout the treatment period. This case highlights the potential of Na1.7 inhibitors in multimodal management of neuropathic pain in animals.

To develop an ultrasound-guided technique for intercostal nerve blocks in rabbit cadavers and to compare the success rate and potential complications of this technique to blind injection.

To investigate the pharmacodynamics and pharmacokinetics of rocuronium administered by bolus injection to sevoflurane-anesthetized horses.

To evaluate dose requirements of etomidate for endotracheal intubation, with or without midazolam co-induction, and to describe induction quality and associated cardiorespiratory variables in healthy cats.

To model pharmacokinetics of three benzodiazepines and their metabolites in sheep.

To characterize the anesthetic effects of dexmedetomidine, vatinoxan and ketamine combinations in cats.

To assess the effect of two different doses of intramuscular atipamezole on head height (HH) in horses after sedation with detomidine.

To investigate the psychological, physical and professional impact of veterinary patient safety incidents (PSIs) on veterinary anaesthesia professionals.

To investigate which breathing systems are available and why they are selected in dogs weighing 5-10 kg.

To evaluate the effect of intravenous (IV) hydromorphone alone or in combination with midazolam or dexmedetomidine on intraocular pressure (IOP) in dogs.

To assess sedation following intramuscular (IM) administration of medetomidine versus medetomidine-vatinoxan in bearded dragons.

To explore the influence of acepromazine on the cardiovascular effects of dobutamine in isoflurane-anaesthetised horses premedicated with romifidine.

To determine whether dogs with magnetic resonance imaging (MRI)-determined intracranial space occupying lesions (MRI-iSOLs) or intracranial hypertension (MRI-ICH) had greater sedation scores and quicker onset of recumbency following premedication with intravenous (IV) butorphanol in comparison with dogs which had normal MRI findings.

To characterize the effect of buprenorphine on the minimum alveolar concentration of isoflurane (MACiso) in cats.

To investigate the haemodynamic effects of gamma-hydroxybutyric acid (GHB) in isoflurane-anaesthetized pigs.

To compare the sedative and physiological effects of intranasal (IN) and intramuscular (IM) delivery of detomidine in calves.

To assess attitudes of Thai veterinarians towards perioperative pain management in dogs and cats, and explore associations between demographic characteristics and use of analgesics and pain assessment.

To compare the behavioural responses of lambs to ring castration with or without local anaesthetic administration by single midline injection at the scrotal neck.