JOURNAL OF SURGICAL ONCOLOGY

Oncoplastic Surgery: Where Are We Now?
Clark P, DiPasquale A, Cocco D, Brown A and Brown A
In the 1970s, we learned breast conservation therapy (BCT) was not inferior to mastectomy. Early BCT methods could result in deformities that were unacceptable to patients and to their surgeons. By the 1990s, surgeons began to apply the principles of plastic surgery to improve outcomes. The term oncoplastic surgery was first described in the 1990s by Werner Audretsch. We offer a review of principles, techniques, current controversies, and challenges in broadening the utilization of OPS.
Analysis of Risk Factors, Treatment Patterns, and Survival Outcomes After Emergency Presentation With Colorectal Cancer: A Prospective Multicenter Cohort Study in Nigeria
Aderibigbe AS, Dare AJ, Kalvin HL, Olasehinde O, Wuraola F, Adisa A, Omisore AD, Komolafe AO, Omoyiola OZ, Okereke CE, Katung A, Egberoungbe A, Ariyibi O, Olatoke SA, Adeyeye AA, Agodirin SO, Bojuwoye MO, Fayenuwo JO, Ademakinwa OR, Osinowo D, Lawal AR, Abdulkareem FB, Goldman D, Knapp G, Murthy S, Kahn R, Gonen M, Kingham TP, Alatise OI and
Prospective data on presentation and outcomes of colorectal cancer (CRC) in Nigeria are limited; however, emergency presentation with advanced disease is thought common.
Recurrence Timing and Risk Following Curative Resection of Colorectal Liver Metastases: Insights From a Hazard Function Analysis
Kawashima J, Akabane M, Endo Y, Woldesenbet S, Altaf A, Ruzzenente A, Popescu I, Kitago M, Poultsides G, Sasaki K, Aucejo F, Sahara K, Endo I and Pawlik TM
There is no consensus on the optimal surveillance interval for patients undergoing resection of colorectal liver metastases (CRLM). We sought to assess the timing and intensity of recurrence following curative-intent resection of CRLM utilizing a recurrence-free survival (RFS) hazard function analysis.
Disparities in Breast Cancer Treatment and Reconstruction Among Native Hawaiian and Pacific Islander Women: Systematic Review and Meta-Analysis
Nguyen A, Duckworth E, Pascua D, Coles B and Galiano R
Native Hawaiian and Pacific Islander (NHPI) women experience significant disparities in breast cancer treatment and outcomes, including lower rates of postmastectomy reconstruction, higher refusal rates of radiation therapy, and delays in surgical care. These disparities contribute to poorer survival and increased complications compared to other racial/ethnic groups. This systematic review and meta-analysis aim to quantify these disparities and assess their impact on breast cancer outcomes in NHPI women.
Comment On "Prognostic Impact of the Cholangiolar Component in Combined Hepatocellular-Cholangiocarcinoma: Insights from a Western Single-Center Study"
You T, Zhang Y and Li S
A Systematic Review and Meta-Analysis of Oncologic Liver Resections in Low- and Middle-Income Countries: Opportunities to Improve Evidence and Outcomes
Khan AH, Mahmud O, Fatimi AS, Ahmed S, Wiener AA, Nishtala MV, Stahl CC, Christensen L, Khan MR, Schwartz PB and Zafar SN
Patients in low- and middle-income countries (LMICs) are disproportionately affected by liver cancers but there is a lack of understanding of their postoperative outcomes. This study aimed to review the current status of research in LMICs regarding outcomes after oncologic hepatectomy and synthesize the data reported in the literature.
The Emerging Role of Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Pancreatic Cancer
Thiels C and Grotz TE
Peritoneal spread is a frequent cause of metastasis in both the synchronous and metachronous settings for patients with pancreatic cancer. Recent improvements in systemic chemotherapy for pancreatic cancer may now allow for the careful selection of patients with oligometastatic disease isolated to the peritoneum who may benefit from consolidative cytoreduction and HIPEC.
The Paradox of Wait and Watch after Total Neoadjuvant Therapy in Ugly Rectal Cancers
Ballal DS and Saklani AP
The Effects of HIPEC on Survival of Gastric Cancer Patients With Peritoneal Metastasis
Ji ZH, Zhao QD and Li Y
Cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) has been recommended by Peritoneal Surface Oncology Group International (PSOGI) and several other academic organizations as the treatment of choice for selected patients with gastric cancer peritoneal metastasis (GCPM). This review updates the recent progress in CRS+HIPEC for GCPM, with particular focus on the potential curing effects of this approach for subclinical GCPM patients.
Role of Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy (CRS/HIPEC) in the Treatment of Peritoneal Carcinomatosis From Small Bowel Adenocarcinoma-A Systematic Review and Meta-Analysis
Fernando DG, Sparapani R and Mogal H
While systemic chemotherapy (SC) is the mainstay of treatment of peritoneal carcinomatosis from small bowel adenocarcinomas (SBA-PC), its efficacy and outcomes remain poor. Therefore, the role of curative-intent surgery needs to be better defined. Using a systematic review and meta-analysis, this study aims to define the role of CRS/HIPEC in patients with SBA-PC.
Challenges in feeding jejunostomy management: A call for better patient support
Zouhri I, Ghanou N, Amrani L, Lahnaoui O, Benkabbou A, El Fassi A, Souni O, El Ahmadi B, Belkhadir ZH and Souadka A
Brachytherapy for Soft Tissue Sarcoma: Maintaining Local Control While Minimizing Complications
Montreuil J, Kholodovsky E, Markowitz M, Torralbas Fitz S, Campano D, Geiger E, Hornicek F, Crawford B, Keisch M and Temple HT
This study aims to assess the clinical and oncologic outcomes of high-dose brachytherapy (BRT) versus both preoperative and postoperative external beam radiation therapy (EBRT) in the setting of high-grade soft tissue sarcoma.
Are Nomograms Useful for Predicting Sentinel Lymph Node Status in Melanoma Patients?
Lourdault K, Cowman AW, Hanes D, Scholer AJ, Aguilar T and Essner R
Clinical nomograms have been developed to predict sentinel lymph node (SLN) status in early-stage melanoma patients, but the clinical utility of these tools remains debatable. We created and validated a nomogram using data from a randomized clinical trial and assessed its accuracy against the well-validated Melanoma Institute Australia (MIA) nomogram.
Gastric Cancer at a Nigerian Tertiary Referral Center: Experiences With Establishing an Institutional Cancer Registry
Yibrehu B, Mohammed TO, Murthy S, Aderibigbe AS, Daramola OB, Arije O, Owoade I, Wuraola FO, Olasehinde O, Betiku O, Folorunso SA, Omoyiola O, Aderounmu A, Adisa AO, Kingham PT and Alatise OI
In Nigeria, gastric cancer is the 10th most common and 9th most deadly malignancy. The limited availability of robust data makes further characterizing it challenging. The objective of this study was to assess the presentation, and management of gastric cancer in Nigeria using an institutional cancer registry.
Complications After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy - Can We Do Better?
Alberto V ME, Zuluaga D, Winter A, Pratschke J, Rau B and Gül S
The main aim of this review is to analyze postoperative complications after cytoreductive surgery and intraperitoneal chemotherapy. Although the literature in this field is ever growing, reporting on complication is not a given. Nevertheless, some main risk factors such as prior surgery, high tumor burden and the center's expertize have an impact on patient outcomes. Transparency is key, if we want to continue to improve.
Staging Approaches to Lymphatic Surgery: Techniques and Considerations
Salibian AA, Yu N and Patel KM
Lymphatic surgery has demonstrated promising outcomes for the treatment of lymphedema alongside nonsurgical techniques. Physiologic lymphatic surgeries including lymphovenous bypass and vascularized lymph node transplants address the fluid burden in lymphedema whereas reductive surgeries including suction lipectomy and excisional techniques address the fibroadipose component of the disease. Lymphedema patients often present with both fluid and fat components that may require different procedures for optimal results. In addition, the chronic, progressive nature of lymphedema can warrant the need for multiple procedures to address different anatomic areas as well as further improve outcomes. This paper reviews the current literature on staging different or repeated lymphatic procedures and proposes an algorithm to navigate physiologic and reductive lymphatic surgery when multiple procedures are needed to optimize surgical outcomes.
The Use of Near-Infrared Indocyanine Green Fluorescence Imaging to Differentiate Benign Versus Malignant Adrenal Tumors
Berber B, Krishnamurthy V and Siperstein A
Despite advances in imaging modalities, a significant number of adrenal tumors are considered indeterminate and removed surgically. Currently, there is no intraoperative tool available to provide further information about the nature of indeterminate adrenal tumors. The aim of this study was to investigate whether near-infrared indocyanine green (ICG) imaging can be used in this regard.
Clinical Trial Access in Diverse Populations
Montaque T and Stewart J
Despite the disproportionate impact of cancer on minority groups, their participation in oncologic clinical trials remains low. Contributing factors include mistrust of the medical establishment, structural barriers, and implicit bias. Strategies to improve access and representation include pragmatic trial designs, patient navigation programs, financial support, and increasing diversity among medical professionals. Addressing these issues is crucial for ensuring equitable healthcare delivery and improving outcomes for underrepresented populations in clinical research.
Adjuvant chemotherapy versus preoperative chemotherapy for gastric cancer treated with curative-intent resection: A propensity score-matched analysis
Pereira MA, Ramos MFKP, Dias AR, Yagi OK, Charruf AZ, de Castria TB and Ribeiro U
Multimodal therapy (MMT), comprising surgery alongside perioperative chemotherapy (PCMT) or adjuvant chemotherapy (ACMT), has demonstrated improve in survival compared with surgery alone for advanced gastric cancer (GC). However, the moment of administering chemotherapy for GC is still a matter of debate. This study aimed to compare PCMT and ACMT in patients with locally advanced GC.
Gastrectomies for the treatment of gastric cancer in a reference cancer center present better pathological results and survival compared to non-specialized hospitals
Ramos MFKP, Pereira MA, Santos SM, Dias AR and Ribeiro-Junior U
Some studies have shown that gastrectomy performed by experienced surgeons in high-volume specialized hospitals with the possibility of complete treatment has better results. This study aimed to compare the results of patients who underwent surgery at a reference center with non-specialized centers.
Textbook outcome for evaluating the surgical quality of gastrectomy
Ramos MFKP, Gusmão JS, Pereira MA and Ribeiro-Junior U
The textbook outcome (TO) is an indicator to evaluate surgical quality based on clinical, pathological, and surgical outcomes.