JOURNAL OF PERIODONTOLOGY

Ridge dimensional changes and implant stability utilizing the osseodensification protocol: A randomized clinical trial
Saqr AM, Ayilavarapu S, Gandhi K, Lee CT and Stylianou P
There is limited evidence on the effect of osseodensification drilling (OD) on alveolar ridge dimension changes and implant stability compared to standard drilling (SD). The purpose of this study was to compare the effect of both drilling protocols on ridge dimensional changes and implant stability.
Salivary advanced glycated end products, their receptors, and aMMP-8 in periodontitis patients with varying glycemic levels: A cross-sectional study
Thomas JT, Joseph B, Varghese S, Kamalasanan Vijayakumari B, Sorsa T, Mauramo M, Anil S and Waltimo T
Advanced glycation end products (AGE) and their receptors (RAGE) have been implicated in developing periodontal complications in diabetic patients. This study aimed to identify salivary AGE, RAGE, soluble RAGE (sRAGE), and active-matrix metalloproteinase-8 (aMMP-8) levels at varying glycemic levels in periodontitis patients.
Appraising the life-course impact of Epstein-Barr virus exposure and its genetic signature on periodontitis
Ye X, Yuan J, Bai Y, Chen Y, Jiang H, Cao Y, Ge Q, Wang Z, Pan W, Wang S and Chen Q
Periodontitis arises from a multifaceted interplay of environmental variables and genetic susceptibility, where microbial infection plays an indispensable part. Epstein-Barr virus (EBV) exposure has long been considered associated with periodontitis activity; however, the causal relationship and genetic connection between them remain unknown.
Impact of nonsurgical periodontal treatment on arterial stiffness outcomes related to endothelial dysfunction: A systematic review and meta-analysis
Polizzi A, Nibali L, Tartaglia GM and Isola G
To assess the available evidence on whether nonsurgical periodontal treatment (NSPT) improves arterial stiffness outcomes in patients with periodontitis (PD).
Artificial intelligence with counseling on the treatment outcomes and quality of life in periodontitis patients
You FT, Lin PC, Huang CL, Wu JH, Kabasawa Y, Chen CC and Huang HL
To evaluate the effects of artificial intelligence (AI)-assisted dental monitoring (DM) with and without health counseling on the treatment outcomes and oral health-related quality of life (OHRQoL) of patients with periodontitis.
Periodontitis associated with brain function impairment in middle-aged and elderly individuals with normal cognition
Ye W, Tao Y, Wang W, Yu Y and Li X
The present study aimed to investigate changes in intranetwork functional connectivity (FC) and internetwork FC in middle-aged and elderly individuals with normal cognition (NC) and varying degrees of periodontitis to determine the effects of periodontitis on brain function.
The impact of intravenous versus submucosal dexamethasone on short-term patient response: A randomized controlled trial
Pearce EP, Deas DE, Powell CA, Diogenes A, Kotsakis GA, Mader MJ and Palaiologou A
The purpose of this randomized, cross-over trial was to determine if a preoperative dose of dexamethasone administered submucosally is as effective as intravenous (IV) dexamethasone in reducing pain, swelling, and analgesic consumption after periodontal flap surgery.
Clinical outcomes of using operating microscope for alveolar ridge preservation: A randomized controlled trial
Sirinirund B, Zalucha J, Rodriguez Betancourt AB, Kripfgans OD, Wang CW, Velasquez D and Chan HL
The use of the operating microscope (OM) for extraction and alveolar ridge augmentation (ARP) is increasing due to enhanced magnification and illumination. The primary objective was to compare the wound healing and crestal bone quality after the use of OM and dental loupes (DL) for ARP.
Gingival inflammation and leukocyte-endothelium cell interactions in women with polycystic ovary syndrome
Márquez-Arrico CF, Silvestre FJ, Fernández-Reyes M, López-Domènech S, Hermenejildo J, Abad-Jiménez Z, Silvestre-Rangil J, Fernández-Collazo P, Morillas C, Montiel-Company JM, Víctor VM and Rocha M
Given the link between chronic inflammation and periodontal pathologies and increased cardiovascular risk, this study aims to investigate if gingivitis exacerbates the inflammatory response and subclinical atherosclerotic markers in women with polycystic ovary syndrome (PCOS).
Effectiveness of nonsurgical re-instrumentation: Tooth-related factors
Bumm CV, Schwendicke F, Pitchika V, Heck K, Walter E, Ern C, Heym R, Werner N and Folwaczny M
To investigate tooth-related factors that influence pocket closure (PC) and the reduction of pocket probing depths (PPD) after nonsurgical re-instrumentation (NSRI) as part of step 3 therapy.
[Not Available]
Okano DK
Impact of smoking habit on the subgingival proteome in patients with periodontitis
Blanco-Pintos T, Regueira-Iglesias A, Kuz I, Sánchez-Barco A, Seijas-Otero N, Chantada-Vázquez MDP, Balsa-Castro C and Tomás I
Few investigations evaluated smoking's impact on the periodontal proteome. Therefore, this study aimed to analyse the influence of tobacco on the overall periodontal proteome and the differential expression of gingival crevicular fluid (GCF) proteins using sequential window acquisition of all theoretical mass spectra (SWATH-MS).
Behçet's disease modifies the gingival inflammatory response
Sahinkaya S, Yilmaz M, Yay E, Toygar H, Balci N, Altinisik DD, Kutlubay Z and Kantarci A
Behçet's disease (BD) pathogenesis involves severe outcomes such as blindness, central nervous system manifestations, and deep venous thrombosis that impacts systemic and local inflammatory changes. We tested the hypothesis that BD negatively affects gingival health and increases the severity of gingivitis.
Evaluation of salivary interleukin-17 and developmental endothelial locus-1 in patients with periodontitis with and without type 2 diabetes mellitus
Zhang Y, Su X, Li Y, Cai Y, Kang N, Duan J, Chen F, Xue F and Chen X
Bidirectional positive relationship between periodontitis and type 2 diabetes mellitus (T2DM) has been recognized, interleukin 17 (IL-17) and developmental endothelial locus-1 (Del-1) are proposed to play roles in periodontitis and T2DM. This study aims to investigate the association of IL-17 and Del-1 in patients with periodontitis with and without T2DM by measuring their salivary levels.
Serum vitamin D concentration is inversely associated with matrix metalloproteinase-9 level in periodontal diseases
Yıldırım YA, Ozturk A, Doğruel F, Saraçoğlu H and Yazıcı C
The aim of this study was to investigate the potential association between vitamin D deficiency and matrix metalloproteinase-9 (MMP-9) levels in gingival crevicular fluid (GCF) across various periodontal health and disease statuses.
Bmi-1 alleviates alveolar bone resorption through the regulation of autophagy
Chu Y, Liu S, Yan L and Gong A
B-cell‑specific Moloney MLV insertion site-1(Bmi-1)is a crucial osteopenic target molecule. The aim of this study is to explore the effects of Bmi-1 on alveolar bone resorption and the underlying mechanisms in vitro and vivo.
A population-based study on the associations of thyroid cancer with chronic periodontitis
Yang TH, Cheng YF, Lin HC and Chen CS
Emerging concerns link periodontitis to an array of cancers, notably thyroid cancer, though investigations into these associations are still in the nascent stages. This population-based study aimed to investigate the association of thyroid cancer with chronic periodontitis using Taiwan's Longitudinal Health Insurance Database 2010 (LHID2010).
Combined application of Er:YAG laser and low-level laser in non-surgical treatment of periodontitis
Cheng Z, Li W, Wang J, Huang X, Jia X and Zhou X
To compare the efficacy of combined treatment of Er:YAG laser (ERL) and low-level laser therapy (LLLT) with single laser applications, and scaling and root planing (SRP) for non-surgical periodontal treatment.
Lipocalin-2 as a fundamental protein in type 2 diabetes and periodontitis in mice
Sólis-Suarez DL, Cifuentes-Mendiola SE, González-Alva P, Rodríguez-Hernández AP, Martínez-Dávalos A, Llamosas-Hernandez FE, Godínez-Victoria M and García-Hernández AL
Lipocalin-2 (LCN-2) is an osteokine that suppresses appetite, stimulates insulin secretion, regulates bone remodeling, and is induced by proinflammatory cytokines. The aim of this work was to investigate the participation of LCN-2 in periodontitis associated with type 2 diabetes (T2D) by evaluating alveolar bone loss, glycemic control, inflammation, and femur fragility.
Effects of a 4-week free-sugar avoidance during periodontal therapy: An explorative randomized controlled clinical trial
Pappe CL, Peters B, Pivovarova-Ramich O, Schremmer R, Adam A, Vach K, Dommisch H and Woelber JP
This study investigated the effect of a 4-week free-sugar avoidance on periodontal parameters during periodontal therapy.
B10 cells regulate macrophage polarization to alleviate inflammation and bone loss in periodontitis
Cao G, Xu Q, Huang S, Dai D, Wang J, Li W, Zhao Y, Lin J and Han X
The polarization of macrophages into an anti-inflammatory phenotype is crucial for resolving periodontal inflammation. It has been reported that B10 cells can regulate the immune response of macrophages during inflammation and are also able to regulate inflammation in periodontitis. However, whether B10 cells' regulation function in periodontitis is related to macrophage polarization remains unclear. This study aims to investigate whether B10 cells can regulate macrophage polarization in periodontitis.