Journal of Pediatric Urology

Editorial
Alkaline urine is associated with increased risk of calcium phosphate nephrolithiasis in medically complex children receiving enteral nutrition
Nehus E, Schulte M, Devarajan P and DeFoor W
Calcium phosphate stones are commonly found in medically complex children (MCC) receiving enteral feeds. The objective of this study is to investigate the etiology for calcium phosphate stones in this patient population.
Predictive variables for successful retrograde intrarenal surgery outcomes in pediatric patients: Development of nomograms
Rosière NI, Ruiz J, López Imizcoz F, Szklarz T, Asen L, Díaz Zabala L, Blain O, Alberti D, Gómez Y, Burek C, Sager C, Sanchez Salinas P, Weller S and Corbetta JP
Pediatric stone disease is characterized by its increasing prevalence and high recurrence rate. Consequently, the use of minimally invasive procedures with high stone-free rates (SFR) is essential. This study aims to identify risk factors associated with the failure of retrograde intrarenal surgery (RIRS) for renal stones smaller than 20 mm in pediatric patients and to develop predictive nomograms for preoperative patient selection. A retrospective analysis of 62 RIRS identified five key factors affecting SFR: stone volume, stone diameter, stone density, the presence of multiple stones, and lower calyx location. Among these variables, independent predictors of success were identified and incorporated into logistic regression models, which were subsequently translated into two nomograms. These represent the first tools specifically designed to predict preoperative SFR in pediatric patients undergoing RIRS. The predictive models developed in this study demonstrated high accuracy in predicting surgical success, providing urologists with reliable tools to individualize treatment planning based on preoperative imaging. Despite these promising results, external validation by high-volume pediatric urology centers is crucial to confirm the generalizability and robustness of these models. These findings represent a significant advancement in the personalized management of pediatric stone disease.
Reducing catheter-associated urinary tract infections with sterile, continuously closed drainage systems does not have to be costly
Fachko TD, Robey CL, Cannon G, Konyk L, Thomas S, Jockel C, Montoya L and Fox JA
Catheter-associated urinary tract infections (CAUTIs) cause significant morbidity and financial strain in the pediatric intensive care unit (PICU). There is a significant incentive to reduce the rate of CAUTIs through multimodal quality improvement initiatives; however, these initiatives are often costly to implement.
The influence of positive and negative intraoperative feedback in laparoscopic simulation in pediatric urology training
Martz N, Lachkar AA, Breaud J, Ali L, Pierucci UM, Talon I, Becmeur F, Julien-Marsollier F, Bidault-Jourdainne V, El-Ghoneimi A and Peycelon M
This study aimed to explore the impact of positive or negative feedback on the performance of trainees in pediatric urology during simulation exercises in pediatric laparoscopy.
Letter to the editors on "International consensus on research priorities in hypospadias using a Delphi study approach"
Sookaromdee P and Wiwanitkit V
Posterior urethral valves: Examining the relationship of socioeconomic factors in disease presentation and progression
Staniorski CJ, Killian M, Rogers D, Flinn J, Chaudhry R and Ayyash O
A significant portion of posterior urethral valve patients continue to progress to end stage renal disease despite improvements in medical care. Socioeconomic status has been connected to various healthcare outcomes but has not been evaluated in relation to longitudinal outcomes of posterior urethral valves.
Boundary tissues and layers in the anatomy of the penis - Comment on 2-stage STAG vs 3-stage STAC for primary proximal hypospadias repair
Özbey H
Response to the Letter to the editors on "International consensus on research priorities in hypospadias using a Delphi study approach"
Abbas TO
Impact of seasonality and ambient temperature on testicular torsion incidence: A Mexican Nationwide population-based study
Arriaga-Izabal D, Morales-Lazcano F and Canizalez-Román A
Testicular torsion is a surgical emergency characterized by twisting the spermatic cord, disrupting blood flow, and causing severe pain and swelling. It predominantly affects males aged 12 to 18, with an incidence of about 3.8 per 100,000 in this age group. Immediate surgical intervention is vital, as irreversible damage can occur within 4-6 h of symptom onset. Recent studies have suggested a correlation between low ambient temperatures and an increased incidence of testicular torsion, particularly in colder months.
Are adult males concerned about the appearance of their circumcision that was done as a newborn?
Giramonti K, Valenty L, Feustel P, Lee J and Rehfuss A
Male circumcision is a common procedure performed in the US, most often during the newborn period. The rate of circumcision revisions has increased over time and are most often performed at a prepubertal age. Requests for circumcision revision are commonly driven by parents' concerns about the penile appearance and how their child will feel about the appearance as an adult.
Response to the editorial commentary on 'When you cannot trust what you see: The confounding effect'
Braga LH, Dönmez Mİ, Nieuwhof-Leppink A, Cascio S, Ching C, Garriboli M, Haid B, Rosoklija I, Nelson CP and Harper L
Adherence to follow-up ten years after hypospadias repair
Batra NV, Heiman J, Koehlinger J, Dangle P, Meldrum KK, Whittam BM, Szymanski KM, Rink RC, Kaefer M, Cain MP, Misseri R and Roth JD
The utilization of a spare ureter to create a continent catheterizable channel to the bladder in pediatric patients
Frank F, Wullich B, Hirsch-Koch K and Marcou M
Clean intermittent catheterization (CIC) has significant advantages over indwelling catheters. To facilitate CIC, a continent catheterizable channel (CCC) to the bladder is required in some cases. The Mitrofanoff appendicovesicostomy (APV) is considered the gold standard for pediatric CCC creation. However, when the appendix is unavailable or unsuitable for the creation of a CCC alternatives are required.
Self-reported outcomes in adults with hypospadias: A meta-analysis of patient satisfaction and quality-of-life metrics
Gunawan IPGF, Abbas T, Situmorang GR, Wahyudi I, Rodjani A, Abdalla D, Joshi PM, Ali M and Raharja PAR
Hypospadias reconstruction seeks to correct structural problems associated with this congenital condition to improve patient quality-of-life (QoL) and overall well-being. While corrective surgery can lead to major functional and psychosocial improvements, some patients experience continuing problems that require additional procedures. This study evaluates patient-reported outcomes (PROs) in hypospadias care, particularly penile satisfaction and QoL after surgery, to fill this essential gap in the literature.
Comparing the incidence of hypospadias across the United States: A contemporary analysis
Lavoie C, Chun B, Au M, Do C, Baker Z, Cortessis V, Sparks SS, Syed H and Chang AY
Hypospadias is a common congenital malformation occurring in up to 80 in 10,00 live male births, with emerging evidence associating exogenous environmental exposures with increased disease incidence. Military personnel are at particularly higher risk for such exposures and indeed, the rate of hypospadias in infant males born to United States military servicewomen deployed during the Gulf War has been reported to be more than 5 times greater compared to undeployed female military personnel.
Pediatric bladder tissue engineering: Where have we been and where do we go next?
Ramakrishnan VM, Thaker H, Ocampo GL, Adam RM and Estrada CR
This review aims to (a) provide a concise overview of early clinical trials in bladder tissue engineering and the associated challenges, (b) evaluate significant advancements over the past 15 years in addressing key limitations in angiogenesis, scaffolding, cell sourcing, and immunomodulation, and (c) explore the individual and synergistic contributions of each domain toward the development of a viable engineered solution.
Predictability of success of endoscopic vesicoureteral reflux treatment utilizing clinical risk factors and intraoperative injection characteristics
Yücel ÖB, Tekin A, Tiryaki S, Avcı D, Özel Y and Ulman İ
The guidelines lack clarity on how to follow the patients after endoscopic treatment for vesicoureteral reflux (VUR). The most discussed question is the need for voiding cystourethrogram (VCUG). Risk-based approaches that consider patient characteristics, disease severity, or factors related to the surgery itself could reduce its use, but a satisfactory predictive model has not yet been established. We hypothesized surgeons can predict the treatment success evaluating the procedure and risk factors and analyzed the assessments of five experts on the subject.
Editorial comment to: When you cannot trust what you see: The confounding effect
Stein R
Novel CO loaded nanoparticle ultrasound-activated contrast agent: A potential urinary catheter-free modality to detect vesicoureteral reflux
Lavoie C, Nussbaum Z, Syed H, Chun B, Do V, Nguyen D, Surapaneni A, Hamid E, Rayes A, De La Torre D, Ramirez O, Rosales E, Williams TJ, Yen JT and Chang AY
The current gold-standard for detecting vesicoureteral reflux (VUR) is the voiding cystourethrogram (VCUG). However, VCUGs require ionizing radiation and bladder catheterization that can be challenging to perform and traumatic for pediatric patients and their parents.
Exploring AI: Transforming medical practice, education and research
Haid B, Nelson C, Dönmez Mİ, Cascio S, Garriboli M, Nieuwhof-Leppink A, Ching C, Braga LH, Rosklija I and Harper L