Epidemiology and Psychiatric Sciences

Self-reports vs clinician ratings of efficacies of psychotherapies for depression: a meta-analysis of randomized trials
Miguel C, Harrer M, Karyotaki E, Plessen CY, Ciharova M, Furukawa TA, Cristea IA and Cuijpers P
The comparability between self-reports and clinician-rated scales for measuring depression following treatment has been a long-standing debate, with studies finding mixed results. While the use of self-reports in psychotherapy trials is very common, it has been widely assumed that these tools pose a validity threat when masking of participants is not possible. We conducted a meta-analysis across randomized controlled trials (RCTs) of psychotherapy for depression to examine if treatment effect estimates obtained via self-reports differ from clinician-rated outcomes.
Timing of exposure to household poverty and adolescent mental health problems
Koyama Y, Isumi A and Fujiwara T
Mental health problems in adolescence are increasingly prevalent and have tremendous impacts on life-long health and mortality. Although household poverty is a known risk factor for adolescent mental health, evidence of the timing hypothesis is scarce. We aimed to examine the longitudinal associations of poverty across childhood with mental health in adolescence, focusing on the timing of exposure.
A cross-country comparison of temporal change in adolescent mental health problems in the UK and Brazil
Armitage JM, Viegas da Silva E, Tseliou F, Riglin L, Hammerton G, Collishaw S, Santos IS, Tovo-Rodrigues L, Menezes AMB, Wehrmeister CF, Gonçalves H, Matijasevich A and Murray J
Epidemiological evidence shows a concerning rise in youth mental health difficulties over the past three decades. Most evidence, however, comes from countries in Europe or North America, with far less known about changes in other global regions. This study aimed to compare adolescent mental health across two population-based cohorts in the UK, and two population-based cohorts in Pelotas, Brazil.
The complete mental health of Australia's adolescents and emerging adults: distress and wellbeing across 3 nationally representative community samples
Crisp D, Rickwood D, Burns R and Bariola E
The high level of psychological distress in young people is a growing concern. However, there are few national surveys that describe the trajectories of mental health and wellbeing through adolescence into early adulthood. Further, existing research has largely focused exclusively on mental ill-health, with little focus on positive mental health. This study provides the first national profile of the mental health and wellbeing of Australians aged 12-25 years.
A population-based cohort study of perinatal mental illness following traumatic brain injury
Brown HK, Fung K, Mataruga A, Strauss R, Chan V, Urbach N, Mollayeva T, Colantonio A, Cohen E, Dennis CL, Ray JG, Saunders NR and Vigod SN
To examine the risk of perinatal mental illness, including new diagnoses and recurrent use of mental healthcare, comparing women with and without traumatic brain injury (TBI), and to identify injury-related factors associated with these outcomes among women with TBI.
A systematic review and meta-analysis of the effect of community treatment orders on aggression or criminal behaviour in people with a mental illness - CORRIGENDUM
Kisely S, Bull C and Gill N
Modelling the impact on a local mental health system of previously implemented care programs: the experience of assertive outreach teams in Bizkaia (Spain)
Almeda N, Diaz-Milanes D, Killaspy H, Salvador-Carulla L, Uriarte-Uriarte JJ and García Alonso CR
The study assessed the interactions and the impact of specialist mobile community care teams (assertive outreach teams or AOTs) implemented in the mental health (MH) system of Bizkaia (Spain) using a methodology derived from an ecosystem perspective.
Effect of a needs-based model of care on the characteristics of healthcare services in England: the i-THRIVE National Implementation Programme
Sippy R, Efstathopoulou L, Simes E, Davis M, Howell S, Morris B, Owrid O, Stoll N, Fonagy P and Moore A
Developing integrated mental health services focused on the needs of children and young people is a key policy goal in England. The THRIVE Framework and its implementation programme, i-THRIVE, are widely used in England. This study examines experiences of staff using i-THRIVE, estimates its effectiveness, and assesses how local system working relationships influence programme success.
The effects of digital peer support interventions on physical and mental health: a review and meta-analysis
Yeo G, Fortuna KL, Lansford JE and Rudolph KD
Digital peer support interventions have the potential to promote healthy lifestyles and better mental health. This systematic review and meta-analysis synthesizes evidence on the effectiveness of digital peer support interventions for enhancing physical and mental health in healthy individuals rather than those diagnosed with a clinical condition.
Treatment rates and delays for mental and substance use disorders: results from the Australian National Survey of Mental Health and Wellbeing
Birrell L, Prior K, Vescovi J, Sunderland M, Slade T and Chapman C
Prompt initial contact with a treatment provider is a critical first step in seeking help for a mental or substance use disorders (SUDs). The aim of the current study was to provide estimates of patterns and predictors of delay in making initial treatment contact based on the recently completed Australian National Survey of Mental Health and Wellbeing.
Internet gaming disorder and depression mediated by impaired resilience and sleep distress: a three-wave longitudinal study among Chinese adolescents
Peng P, Chen ZM, Ren SL, He Y, Li JG, Liao AJ, Zhao LL, Shao X, Chen SS, He RN, Liang YD, Tan YG, Chen XG, Liao YH and Tang JS
While the cross-sectional relationship between internet gaming disorder (IGD) and depression is well-established, whether IGD predicts future depression remains debated, and the underlying mechanisms are not fully understood. This large-scale, three-wave longitudinal study aimed to clarify the predictive role of IGD in depression and explore the mediating effects of resilience and sleep distress.
Towards person-centered care in global mental health: implications for meta-analyses and clinical trials
Papola D and Patel V
Increased risk of suicide among patients with social anxiety disorder
Wei HT, Tsai SJ, Cheng CM, Chang WH, Bai YM, Su TP, Chen TJ and Chen MH
Increasing evidence has established a strong association between social anxiety disorder and suicidal behaviours, including suicidal ideation and suicide attempts. However, the association between social anxiety disorder and suicide mortality remains unclear.
Husband involvement in antenatal care moderates the link between vitamin D status and depressive symptoms in pregnant women
Wong RS, Tung KTS, Tsang HW, Ko JKY, Leung WC and Ip P
The association between a pregnant mother's vitamin D status and depressive symptoms has yielded inconsistent results. It is possible that other factors play a role in this association, as depression can have multiple causes. Recognizing the significance of the husband's participation in antenatal care, this study aimed to examine whether the husband's involvement moderates the link between the mother's vitamin D status and depressive symptoms during pregnancy.
A systematic review and meta-analysis of the effect of community treatment orders on aggression or criminal behaviour in people with a mental illness
Kisely S, Bull C and Gill N
There has been concern about violent acts and other criminal behaviour by people with a possible history of mental health problems. We therefore assessed the effects of community treatment orders (CTOs) on self-, third-party-, and agency-reported criminal behaviour when compared to voluntary treatment.
Three-year course of clinical high-risk symptoms for psychosis in the community: a latent class analysis
Michel C, Osman N, Rinaldi G, Schimmelmann BG, Kindler J and Schultze-Lutter F
Clinical high-risk for psychosis (CHR-P) states exhibit diverse clinical presentations, prompting a shift towards broader outcome assessments beyond psychosis manifestation. To elucidate more uniform clinical profiles and their trajectories, we investigated CHR-P profiles in a community sample.
Facing the paradox of professionalizing peer roles in MH services: how addressing self-disclosure with self-determination theory might help
Moran GS
Peer Support Workers (PSWs) play a crucial role in recovery-oriented mental health services. They offer support and hope by sharing their personal experiences and recovery journeys. However, transitioning from voluntary self-help roles to paid positions within statutory systems is not merely a technical shift. This change creates inherent tensions and conflicts, stemming from the integration of a peer model within a medical framework. I refer to the interface between these models as the "Professional-Peer Paradox" (PPP). At its heart, this paradox questions whether and how PSWs can integrate a role that relies on self-disclosure of shared lived experiences within a system rooted in professional knowledge norms delivered unidirectionally to service recipients. Using a whole organizational approach, I propose leveraging the autonomy-supportive environment concept from self-determination theory (SDT; Deci & Ryan, 2000) to promote self-disclosure in mental health services. I highlight the complexities involved in Peer Support Workers' (PSWs) use of self-disclosure (lived experience) within statutory mental health (MH) services. I suggest that PSWs can better commit to their unique roles by structuring multiple peer roles with varying levels of self-disclosure and creating a culture that fosters peer practice. Overall, applying a SDT systems' framework to the practice of self-disclosure can enhance the occupational identity of PSWs, establishing their unique position within the spectrum of mental health professions globally.
Interrelationships between social exclusion, mental health and wellbeing in adolescents: insights from a national
Filia K, Teo SM, Brennan N, Freeburn T, Baker D, Browne V, Watson A, Menssink J, Prasad A, Killackey E, McGorry PD, Cotton SM and Gao CX
Adolescence is a critical developmental phase during which young people are vulnerable to the experiences of mental ill-health and social exclusion (consisting of various domains including education and employment, housing, finances and social supports and relationships). The aims of this study were to (i) obtain an understanding of the relationships between social exclusion, mental health and wellbeing of young people; and (ii) identify potentially modifiable targets, or population groups that require greater or targeted supports.
Associations between social determinants of health and mental health disorders among U.S. population: a cross-sectional study
Tanarsuwongkul S, Liu J, Spaulding M, Perea-Schmittle K, Lohman M and Wang Q
The impact of social determinants of health (SDOH) on mental health is increasingly realized. A comprehensive study examining the associations of SDOH with mental health disorders has yet to be accomplished. This study evaluated the associations between five domains of SDOH and the SDOH summary score and mental health disorders in the United States.
Exploring socio-economic inequalities in mental healthcare utilization in adults with self-reported psychological distress: a survey-registry linked cohort design
Muwonge JJ, Dalman C, Burström B, Jablonska B and Hollander AC
Although individuals with lower socio-economic position (SEP) have a higher prevalence of mental health problems than others, there is no conclusive evidence on whether mental healthcare (MHC) is provided equitably. We investigated inequalities in MHC use among adults in Stockholm County (Sweden), and whether inequalities were moderated by self-reported psychological distress.
Childhood contact with social services, self-harm and suicidal or self-harm ideation in young adulthood: a population-wide record-linkage study
McKenna S, O'Reilly D, Ross E and Maguire A
Childhood contact with social services is associated with a range of adverse mental health outcomes across the life course, yet there is limited evidence in relation to self-harm and suicidal or self-harm ideation.
Is there a mental health diagnostic crisis in primary care? Current research practices in global mental health cannot answer that question
Kohrt BA, Gurung D, Singh R, Rai S, Neupane M, Turner EL, Platt A, Sun S, Gautam K, Luitel NP and Jordans MJD
In low- and middle-income countries, fewer than 1 in 10 people with mental health conditions are estimated to be accurately diagnosed in primary care. This is despite more than 90 countries providing mental health training for primary healthcare workers in the past two decades. The lack of accurate diagnoses is a major bottleneck to reducing the global mental health treatment gap. In this commentary, we argue that current research practices are insufficient to generate the evidence needed to improve diagnostic accuracy. Research studies commonly determine accurate diagnosis by relying on self-report tools such as the Patient Health Questionnaire-9. This is problematic because self-report tools often overestimate prevalence, primarily due to their high rates of false positives. Moreover, nearly all studies on detection focus solely on depression, not taking into account the spectrum of conditions on which primary healthcare workers are being trained. Single condition self-report tools fail to discriminate among different types of mental health conditions, leading to a heterogeneous group of conditions masked under a single scale. As an alternative path forward, we propose improving research on diagnostic accuracy to better evaluate the reach of mental health service delivery in primary care. We recommend evaluating multiple conditions, statistically adjusting prevalence estimates generated from self-report tools, and consistently using structured clinical interviews as a gold standard. We propose clinically meaningful detection as 'good-enough' diagnoses incorporating multiple conditions accounting for context, health system and types of interventions available. Clinically meaningful identification can be operationalized differently across settings based on what level of diagnostic specificity is needed to select from available treatments. Rethinking research strategies to evaluate accuracy of diagnosis is vital to improve training, supervision and delivery of mental health services around the world.
Persistence of anxiety and depression symptoms and their impact on the COVID-19 vaccine uptake
Shen Y, Penrose K, Robertson M, Piltch-Loeb R, Fleary S, Kulkarni S, Teasdale C, Balasubramanian S, Yadav S, Chan BXJ, Sanborn J, Sahr JN, Srivastava A, Nash D and Parcesepe A
The enduring impact of the COVID-19 pandemic on mental health and its implications for COVID-19 vaccine uptake necessitate comprehensive investigation. We aimed to characterize the persistence of moderate to severe anxiety and depression symptoms from July 2020 to July 2023, explore demographic associations with symptom persistence, and assess how these symptoms affected COVID-19 vaccination uptake between May 2021 and July 2023.
Bidirectional analysis of the association between migraine and post-traumatic stress disorder in Nurses' Health Study II
Crowe HM, Sampson L, Purdue-Smithe AC, Rexrode KM, Koenen KC and Rich-Edwards JW
Migraine and post-traumatic stress disorder (PTSD) are both twice as common in women as men. Cross-sectional studies have shown associations between migraine and several psychiatric conditions, including PTSD. PTSD is disproportionally common among patients in headache clinics, and individuals with migraine and PTSD report greater disability from migraines and more frequent medication use. To further clarify the nature of the relationship between PTSD and migraine, we conducted bidirectional analyses of the association between (1) migraine and incident PTSD and (2) PTSD and incident migraine.
Adverse childhood experiences and subsequent experiences of intimate partner violence in adulthood: a gender perspective
Tian Z, Zhang N, Li Y, Wu Y and Wang L
Investigate the prevalence of adverse childhood experience (ACE) and intimate partner violence (IPV) using a large representative Chinese sample, explore the association mechanism between ACE and adult exposure to IPV and to examine gender differences.
A longitudinal birth cohort study of child maltreatment and mental disorders using linked statewide child protection and administrative health data for 83,050 Queensland residents from 1983 to 2014 - ERRATUM
Kisely S, Leske S, Ogilvie J, Thompson C, Siskind D and Allard T
War exposure, daily stressors, and mental health 15 years on: implications of an ecological framework for addressing the mental health of conflict-affected populations
Miller KE and Rasmussen A
Fifteen years ago, we published an article in seeking to resolve the contentious debate between advocates of two very different frameworks for understanding and addressing the mental health needs of conflict-affected populations. The two approaches, which we labelled and , reflect deeply held beliefs about the causes and nature of distress in war-affected communities. Drawing on the burgeoning literature on armed conflict and mental health, the reports of mental health and psychosocial support (MHPSS) staff in the field, and on research on the psychology and psychophysiology of stress, we proposed an integrative model that drew on the strengths of both frameworks and underscored their essential complementarity. Our model includes two primary pathways by which armed conflict impacts mental health: directly, through exposure to war-related violence and loss, and indirectly, through the harsh conditions of everyday life caused or exacerbated by armed conflict. The mediated model we proposed draws attention to the effects of stressors both past (prior exposure to war-related violence and loss) and present (ongoing conflict, daily stressors), at all levels of the social ecology; for that reason, we have termed it an ecological model for understanding the mental health needs of conflict-affected populations.
Rates of colorectal cancer diagnosis and mortality in people with severe mental illness: results from Australia's National Bowel Cancer Screening Programme
Kisely S, Spilsbury K, Bull C, Jordan S, Kendall BJ, Siskind D, Sara G, Protani M and Lawrence D
Studies show that people with severe mental illness (SMI) have a greater risk of dying from colorectal cancer (CRC). These studies mostly predate the introduction of national bowel cancer screening programmes (NBCSPs) and it is unknown if these have reduced disparity in CRC-related mortality for people with SMI.
Social disconnectedness, subsequent medical conditions, and, the role of pre-existing mental disorders: a population-based cohort study
Laustsen LM, Lasgaard M, Momen NC, Chen D, Gradus JL, Grønkjær MS, Jensen MM and Plana-Ripoll O
Individuals with diminished social connections are at higher risk of mental disorders, dementia, circulatory conditions and musculoskeletal conditions. However, evidence is limited by a disease-specific focus and no systematic examination of sex differences or the role of pre-existing mental disorders.
Twelve-month follow-up of a controlled trial of a brief behavioural intervention to reduce psychological distress in young adolescent Syrian refugees
Bryant RA, Habashneh R, Ghatasheh M, Malik A, Aqel IS, Dawson KS, Watts S, Jordans MJD, Brown FL, van Ommeren M and Akhtar A
The majority of studies of mental health interventions for young adolescents have only evaluated short-term benefits. This study evaluated the longer-term effectiveness of a non-specialist delivered group-based intervention (Early Adolescent Skills for Emotions; EASE) to improve young adolescents' mental health.