Enhancing Future Research and Clarifying the Role of Minocycline in Refining Delirium Prevention in Critical Care
Prophylactic Minocycline for Delirium With Unexpected Death Benefits: What Was Treated Unexpectedly?
Improving Diagnosis and Management of Pulmonary Hypertension in Interstitial Lung Disease
Are Lung Ultrasound B-Lines Better Than Pulmonary Function Tests in Predicting the Prognosis of Patients With Systemic Sclerosis?
Reflections on the Recent Study on Minocycline for Delirium Prevention in Patients in the ICU
Lung Nodules and Masses in non-HIV Immunocompromised Patients: A Clinical-Imaging Algorithmic Approach
The incidence of pulmonary nodules and masses in non-HIV immunocompromised patients has significantly increased due to advancements in hematopoietic stem cell transplantation (HSCT), solid organ transplantation (SOT), and the widespread use of chemotherapy and immunosuppressive therapies. Differentiating between infectious and non-infectious causes is critical for appropriate diagnosis and management, especially as radiological and clinical presentations can be nonspecific.
Effects of β-blockers on the Outcomes in Patients with Pulmonary Arterial Hypertension Stratified by the Presence of Comorbid Conditions: a Multicenter Prospective Cohort Study (BNP-PL)
The current guidelines do not recommend β-blockers in pulmonary arterial hypertension (PAH) unless indicated by comorbidities. However, the evidence regarding the role of β-blockers in PAH is contradictory.
Quantitative Computed Tomography Analysis in Rheumatoid Arthritis-Related Interstitial Lung Disease
Quantitative chest computed tomography (CT) may be a useful predictor of outcome in rheumatoid arthritis-related interstitial lung disease (RA-ILD).
Results of the SHARP Study: A Randomized, Placebo-Controlled, Double-Blind, Repeated-Measures, Crossover, Phase IV Clinical Trial of the Effect of the Wake-Promoting Agent Solriamfetol on Cognitive Function in Obstructive Sleep Apnea With Excessive Daytime Sleepiness and Cognitive Impairment
Obstructive sleep apnea (OSA) causes episodes of fragmented sleep and intermittent hypoxia and leads to excessive daytime sleepiness (EDS). Deficits in cognitive function are a troublesome symptom in patients with OSA and EDS.
Associations of socioeconomic status and phenotypic frailty with incident chronic obstructive pulmonary disease: findings from UK Biobank participants
The independent, mediation, interaction, and joint effects of socioeconomic status (SES) and phenotypic frailty on the incidence of chronic obstructive pulmonary disease (COPD) are unclear.
Dietary pattern, sputum DNA methylation, and lung health: an epidemiological study in people who ever smoked
We previously identified a panel of sputum DNA methylation that predicts lung ageing and risk for lung cancer.
Sarcoidosis Treatment Patterns in the United States: 2016-2022
There are limited FDA-approved medications and real-world data on sarcoidosis treatment in the U.S. and concordance of practice patterns with guideline recommendations have not been well characterized.
Comparison of clinically meaningful improvements following center-based and home-based tele rehabilitation in people with COPD
Response to pulmonary rehabilitation is not equal for all participants, and may vary across health outcomes for any one individual. Alternative modes of pulmonary rehabilitation delivery, e.g. telerehabilitation, may improve program access but could also affect response to rehabilitation.