Scalds account for 40 % of burn injuries in developed countries, with a subset occurring during caregiving activities, particularly when gloves are worn. Gloves, a standard precaution against infection and body fluid exposure, may impair sensory feedback critical for detecting temperature changes, potentially increasing the risk of burns during personal care tasks.

Skin microbiome dysbiosis can cause skin barrier dysfunction and stimulate scar property change. Skin barrier disruption post-burn injury leads to an imbalance in skin microbe diversity and distribution. We aimed to examine the changes in the skin microbiome of re-epithelialized burn scars.

Burns among children and adolescents represent a significant global health burden, leading to substantial morbidity and disability. This study aimed to analyze the trends in burn incidence, prevalence, and years lived with disability (YLDs) from 1990 to 2021, and to project future trends to 2035, highlighting global and regional disparities.

To investigate coagulation disorders and thrombotic complications in the early stage after burn, and to evaluate the predictive reliability of D-dimer for deep vein thrombosis (DVT) diagnosis in major burn patients.

A better understanding of how major burns patients recover following injury is vital in assessing trauma care and informing healthcare and rehabilitation provision. We aimed to describe the longer-term health and return to work status of major burns patients and identify factors associated with positive outcomes i.e., reporting no problems with health-related quality of life, returning to work).

Severe burns place patients in a compromised state, especially those with pre-existing chronic diseases such as malignancy. Due to improvements in detection and treatment, cancer mortality has declined significantly, leaving a growing population of cancer survivors. Therefore, we wondered whether pre-existing cancer diagnoses influence patient outcomes following burn injury.

On June 13, 2020, an explosion involving a liquefied natural gas (LNG) tanker truck occurred in eastern China. Fifteen patients with extremely severe burns (referred to as "June 13" patients) were treated in the burn-intensive care unit (ICU) joint ward within the general ICU.

Keloid is a benign skin tumor that result from abnormal wound healing and excessive collagen deposition. The pathogenesis is believed to be linked to genetic predisposition and immune imbalance, although the precise mechanisms remain poorly understood. Current therapeutic approaches may not consistently yield satisfactory outcomes and are often accompanied by potential side effects and risks. The high recurrence rate and refractory nature of keloid nodules present significant challenges and uncertainties in their management. Given the lack of effective treatment strategies, it is essential to identify key molecular pathways and potential therapeutic targets for keloid.

Keloids are a common complication that occurs after injury. The pathogenesis of this disease remains unknown. Therefore, identifying immune-related biomarkers and macrophage polarization types in keloids can provide new insights into their treatment.

Accurate burn depth assessment is critical for determining appropriate treatment and optimizing patient outcomes. Conventional methods, such as clinical assessment and laser Doppler imaging, have limitations in terms of accuracy and timeliness. Spectral imaging, including multispectral imaging and hyperspectral imaging, has emerged as a promising non-invasive modality to improve burn depth evaluation. This systematic review aims to evaluate the advances in spectral imaging technologies for burn depth assessment, with a focus on diagnostic accuracy, the role of machine learning integration, and the quality of current evidence.

Burn injuries can significantly affect a person's ability to function and reduce their quality of life. This study used thermal imaging to investigate the relationship between blood flow changes and healing in second-degree burns. The researchers hypothesized that improved blood flow to the burn site, as indicated by infrared thermography assessments, may be associated with better wound healing outcomes in patients with second-degree burns.

In the burn affected area of the skin, the progression or deepening of wounds is related to oxidative stress. Especially in the highly susceptible stasis zone, tissues survive to the extent that they can cope with oxidative stress.

Skin injuries like superficial burns and skin graft donor sites are currently managed using various dressings. Frequent challenges include discomfort and trauma during dressing changes, suboptimal healing and significant scarring. Silk dressings show promise by reducing the need for frequent changes, allowing wound evaluation due to its transparency, exerting antibacterial properties, and minimizing scarring. However, silk is not yet widely adopted in clinical settings.

Split-thickness skin autografts are the gold standard for surgical treatment of burns. In preclinical studies, the use of SKINHEALTEX PLGA, an electrospun poly(lactic-co-glycolide) acid (PLGA) bioveil, placed between autografts and their bed has shown potential to stimulate dermal regeneration, increase graft take and improve scar quality. These properties have not yet been evaluated in human clinical trials.