BURNS

A prospective multicenter non-inferiority trial to evaluate a new burn rehabilitation program based on the International Classification of Functioning, Disability and Health (ICF)
Harhaus L, Ziegenthaler H, Neubauer H, Klimitz FJ, Strupat M, Ripper S, Kneser U and Stolle A
Burn injuries have a lasting impact on physical and psychological health. This study evaluated outcomes for two burn-specific rehabilitation programs based on the International Classification of Functioning, Disability, and Health (ICF) model.
Film fixation for facial burns: Sandwich technique and 3D silicone facemask
Lian C, Li XL, Liu XJ and Zhang XF
Dermatological diseases in conflict areas: A neglected crisis
Këlliçi S, Puca E, Fida M, Puca E and Çomo N
Editorial: New directions for Burns in 2025
Cancio LC
Suprathel's usability and effectiveness for the treatment of paediatric partial thickness burns: a 10-year retrospective cohort study
van de Warenburg MS, El Yadari S, Hummelink S, Ulrich DJ and Vehmeijer-Heeman M
Suprathel has been introduced in our centre since 2014 for superficial to deep partial thickness burns. To evaluate healing outcomes and usability of Suprathel in our paediatric population, we conducted a retrospective cohort study, including all paediatric patients treated with Suprathel for burn wounds since its introduction. The studied population consisted of 92 patients, with a mean age of 4 years [3 months -17 years]. The median wound healing time for the entire cohort was 12.5 days, with no significant differences between the age groups. If wounds were found to be colonized during treatment, the majority of pathogens were Staphylococcus aureus (55.8 %). Seven percent of the patients required a split-thickness skin graft after approximately ten days. The use of Suprathel as epidermal dressing for treatment of partial thickness burns in the paediatric population demonstrates favourable adherence to the wound bed, and reduces the need for frequent dressing changes; the lack of increased wound infections underscore its benefits in paediatric burn care. Our findings suggest no significant differences in outcomes based on the timing of application, wound location, or wound bed preparation, and confirms its efficacy in mobile areas such as the hands.
Kitchen cooking burns: A real danger for adults and children in Ghana
Codjoe AB, Asare LS, Tettey P, Ochieng C, Amegbor P, Boateng G, Sackey B, Addade M, Norvivor FA and Quansah R
In many low- and middle-income countries (LMICs), stove and fuel stacking are frequent practices. However, the impact of stacking on health, particularly cooking-related burns (CRBs), is unknown. This study aims to examine the prevalence and severity of CRBs and to identify associated household factors. Emphasis was placed on cooking behaviors and practices (i.e., fuel choice and stacking) that influence CRBs.
Identification of lncRNA biomarkers for keloid diagnosis and functional characterization of CPEB2-AS1
Xu S, Jiang Y, Zhu X, Rao Y, Zhang M and Lu Y
Keloids are pathological scars marked by excessive tissue growth, and their diagnosis currently depends on clinical observation, lacking objective biomarkers. Although the regulatory role of long non-coding RNAs (lncRNAs) in various diseases has drawn attention, their function in keloids remains unclear.
Nonfatal hospital-treated pediatric and adolescent burn cases in the United States: A 2019-2022 National Electronic Injury Surveillance System analysis
Hoffman RK, Lawrence BA, Ali B, Leonardo J and Miller TR
Burn injuries experienced by infants, children, and adolescents are prevalent and costly-psychologically, physically, and economically. Previous studies have acknowledged the dangers of pediatric burns; however, the literature was missing a thorough portrayal of the contemporary pediatric and adolescent burns landscape in the United States. The current study used 2019-2022 National Electronic Injury Surveillance System (NEISS) data to describe nonfatal pediatric and adolescent burn cases, including prevalence, burn type, body parts affected, product involvement, and differences by age and sex. We identified 300,541 burn survivors among children 0-19 in the 2019-2022 NEISS data. Burn injuries were most experienced by children under 5, especially among 1- and 2-year-olds. More boys than girls were burn victims, with the sex difference most noticeable among the youngest and oldest age groups. Over 94 % of pediatric and adolescent burn cases were categorized as thermal, scald, or chemical. Scald burns were the only type that affected a higher percentage of girls than boys. Hot water was the item most often involved in pediatric and adolescent burn cases, and the hand was the body part most often affected. These findings both corroborate and extend the pediatric burns literature. Identifying the most frequent burn profiles by age, sex, type, body parts affected, and product involved among children and adolescents 0-19 in the United States enabled us to pinpoint risk factors and offer guidance on prevention.
Impact of dysglycemia during the ebb and flow phases of critically ill burn patients: An observational study
Haehn N, Huehn M, Ralser M, Ziles D, Marx G, Mossanen JC, Schaefer B, Beier JP, Breuer T and Deininger MM
Critically ill burn patients face severe metabolic stress, divided into early ebb and late flow phases, causing dysglycemia. While detrimental effects of hyper- and hypoglycemia in burn patients have been reported over the entire stay, its impact during the ebb and flow phases remains unexplored. This study is the first to investigate phase-separated dysglycemia for outcome prediction.
Biomechanical and histological outcomes of a cervical expander capsule
Li R, Cao Z, Yang J, Li W, Wang G, Gan C, Yue Q and Liu L
An expander capsule is a fibrous membrane that forms around a tissue expander. However, its outcome is still unclear. Here we investigated the biomechanical and histological outcomes of cervical capsules that were left in vivo after expanders were removed.
The Shah Suit - A bespoke dressing for paediatric patients with non-burn skin loss
Radcliffe K, Karangura A, Rivers C and Shah M
Lateral thinking: different perspectives on burn care
Khan MAA and Ma Y
World burn care and the multidisciplinary team
Ma Y, Stewart G, Chipp E and Bache S
Burn care is a multifaceted, multiparametric and multimodal process that requires a multidisciplinary team to improve patient outcomes and skills of health professionals through standardisation, regardless of the environment. This work proposes a framework of personal quality improvement that aims to provide a basis for an effective multidisciplinary team that can deliver harmonisation of clinical practice based on practice guidelines and minimise the micro and macro barriers adding to the global burden of burn care. The key focus of the framework is on the effort to closely engage and merge with the larger systems of healthcare as well as with colleagues and the public to create a 'wider multidisciplinary team'. This would help broaden the scope of influence and impact of any changes made to burn care. In this way, communication, coordination and shared decision-making between various professionals are fundamental principles of achieving excellent quality of care.
Have the recent advancements in wound repair and scar management technology improved the quality of life in burn patients?
Atiyeh B, El Hachem TF, Chalhoub R and Emsieh SE
The negative physical and psychosocial impact of scars, in particular burn scars, has been well documented. Altered personal appearance together with impaired function related to pain, heat intolerance, and contracture formation may last a lifetime and eventually can lead to low self-esteem and poor social and psychological adjustments. Though most patients recover within the first years and many report generally good life satisfaction and moderate quality of life (QoL), some severely burned patients continue to report impaired QoL almost 10 years after injury. It is repeatedly mentioned in the literature that patients' QoL and health-related quality of life (HRQoL) can be improved by improving wound healing and burn scar quality. Determining whether advances in burn wound healing and scar management modalities are positively impacting the lives of surviving patients is the aim of this review.
Validity of laser speckle contrast imaging for predicting wound healing potential in burns: A critical examination
De Mey K, De Decker I, Gush R, Hoeksema H, Verbelen J, De Coninck P, Blondeel P, Monstrey S and Claes KEY
Accurate assessment of burn depth is imperative for the efficacious management of burns. Although clinical assessment is commonly used, its accuracy ranges only between 50 % and 70 %. Laser Doppler imaging (LDI) is considered as a gold standard - with an accuracy exceeding 95 %, - for the objective measurement of Healing Potential (HP), HP being the output of the LDI device, as colour-coded on LDI blood flow images. Despite its proven efficacy, widespread adoption is impeded by practical challenges. Laser Speckle Contrast Imaging (LSCI) emerges as a possible alternative. This study investigated the performance and accuracy of LSCI in comparison with LDI for predicting the HP of burns; LDI was assumed to provide 'ground truth' for the assessment of HP.
Prazosin for the treatment of nightmares in hospitalized adult burn patients
Richardson CS, Hatch ES, Nakamura ZM, King BT, Williams FN and Laughon SL
Acute stress disorder (ASD) and post-traumatic stress disorder (PTSD) can occur after a traumatic event; they are characterized by, among other symptoms, hypervigilance, dissociation, nightmares, and flashbacks. Prazosin, an alpha-1 receptor antagonist, has been shown to be effective in reducing nightmares related to ASD and PTSD. Burn patients are particularly susceptible to acute and post-traumatic stress symptoms, especially nightmares. The goal of this study is to examine the benefits of prazosin in treating nightmares, one of the common symptoms of ASD and PTSD, among a cohort of adult burn patients during their hospitalization. We performed a retrospective analysis of 45 hospitalized burn patients who met eligibility criteria admitted between August 2014 and January 2024 who received prazosin to treat trauma-related nightmares. Descriptive statistics were used to characterize response of nightmares to prazosin and adverse effects from prazosin. Twenty-three (51.1 %) patients had full remission of nightmares, 16 (35.6 %) had some improvement in nightmares, and 6 (13.3 %) patients had no improvement in nightmares. Prazosin was well tolerated and there were no clinically significant changes in blood pressure or heart rate. This study suggests that prazosin may be beneficial for the treatment of nightmares associated with burn trauma in the hospital setting.
Coagulation abnormalities in major burn patients: Insights and future considerations
Kamrava A and Aali S
Continuous renal replacement therapy fluid for burn resuscitation: A solution during nationwide fluid shortages
Bryant ML, Sullivan LS and Williams LA
Do allografts present a risk to burn patients? Allografts and HLA-sensitization
Tsai J, Kim L, Jones I, Culbert S and Ozyurekoglu T
This meta-analysis aimed to quantify sensitization rates following allograft usage and determine whether allografts have an increased risk of long-term sensitization compared to alternative therapies in burn patients.
Open label randomized controlled trial of the efficacy and safety of NexoBrid compared to standard of care in children with burns
Shoham Y, Rosenberg L, Narayan RP, Staubach R, Bene R, Kakola M, Monstrey SJ, Wilson Y, Jha M, Lewis GM, Larson S and Singer AJ
This study evaluated the safety and efficacy of an enzymatic bromelain-based debridement (BBD) agent (NexoBrid®) in children with deep thermal burns.
Cling film in pediatric burns: From temporary dressing to therapeutic innovation
Lian C, Li XL, Liu XJ and Zhang XF