Efficacy of a new delivery system based on solid lipid microparticles for the oral administration of the non-conventional antioxidant IAC on a diabetes mouse model
We previously showed the positive effects of the new antioxidant molecule bis(1-hydroxy-2,2,6,6-tetramethyl-4-piperidinyl)-decandioate (IAC) in reducing basal hyperglycaemia and relieving glucose intolerance in a diabetes model. However, the chemical properties of IAC did not allow an efficient oral administration, thus representing the main failing of that study. Here, we tested the effect of a new oral delivery system based on solid lipid microparticles (SLMs) in a diabetes mouse model.
The combined effect of Sango sprout juice and caloric restriction on metabolic disorders and gut microbiota composition in an obesity model
The main purpose of this study was to compare the benefits of SSJ supplementation in obese rats with those achieved only by switching the alimentary regimen from high-fat (HFD) to the regular one (RD) in liver, ileum and prostate. Furthermore, changings in caecal chime microbiota were investigated. SSJ was administered to rats in combination with a RD (HFD-RD + SSJ). The switch from HFD to RD led to a weight loss of almost 9.8 g, and the total cholesterol was found to be significantly lower. In the HFD-RD + SSJ group, all values were improved compared with the HFD control, and the weight decrement was higher (-23.29 g) with respect to HFD-RD. HFD led to a widespread increment of oxidative stress (OS) markers in liver, ileum and prostate. SSJ has shown to improve the results achieved by the suspension of HFD and it has proven effective wherever the only switch in diet regimen failed.
"Wild Indians," "Mexican gentlemen," and the lessons learned in the Casa del Estudiante Indigena, 1926-1932
Affectionate mothers and the colossal machine: feminism, social assistance and the state in Uruguay, 1910-1932
Children of the patria: representations of childhood and welfare state ideologies at the 1922 Rio de Janeiro International Centennial Exposition
Gender, welfare and the Catholic Church in Argentina: conferencías de señoras de San Vicente de Paul, 1890-1916
Populist anxiety: race and social change in the thought of Romulo Gallegos
The "alienated" body: slaves and castas in the Hospital de San Bartolome in Lima, 1680 to 1700
"The purity of my blood cannot put food on my table": changing attitudes towards interracial marriage in nineteenth-century Buenos Aires
Workers' health and colonial mercury mining at Hhuancavelica, Peru
Marriage as slave emancipation in seventeenth-century rural Guatemala
Silencing the unmentionable: non-reproductive sex and the creation of a civilized Argentina, 1860-1900
Widows' rights questioned: Indians, the state, and fluctuating gender ideas in central highland Ecuador, 1870-1900
The devil and modernity in late nineteenth-century Buenos Aires
Rural health and state construction in post-revolutionary Mexico: the Nicolaita project for rural medical services
Coercion, reform, and the welfare state: the campaign against "begging" in Mexico City during the 1930s
Vanishing Indians: the social construction of race in colonial Sao Paulo
Tales of two women: the narrative construal of Porfirian reality
Conspicuous benevolence: liberalism, public welfare, and private charity in Porfirian Mexico City, 1877-1910
Female apostolates and modernization in mid-nineteenth century Chile
[Useful citizens for the fatherland: the education of the "daughters of the people" in Argentina, 1884-1916]
