Research on working memory (WM) training reveals significant variability in training effects, indicating that pretraining cognitive abilities might account for these differences. However, consensus on whether higher (magnification account) or lower (compensation account) pretraining abilities predict greater training effects remains elusive. Our study aimed to clarify the role of fluid reasoning in predicting training performance (i.e. training scores at each session) and gains on near transfer WM tasks. We conducted two studies: Study 1 focused on middle-aged adults (47-65 years) and Study 2 on older adults (65-83 years). Participants in both studies were randomly assigned to either adaptive -back training or an active control group and have all completed three WM tasks before and after 20 training sessions - the trained -back task and two structurally different untrained tasks. Generally, greater average training scores were found in individuals with higher fluid reasoning for both age groups, although this trend did not reach statistical significance in older adults. Similarly, higher fluid reasoning predicted greater training gains only in the sample of middle-aged adults. Further analysis showed that both, middle-aged and older participants in the training groups exhibited higher gains on the trained -back task but not on two other WM tasks. Additionally, fluid reasoning predicted -back gains in both the training and control group. Consistent with a growing body of research, our results show limited generalization of training effects across untrained tasks. It seems that factors beyond pretraining ability should be considered when explaining between-participant differences in training performance.

Greater neighborhood disadvantage is associated with poorer global cognition. However, less is known about the variation in the magnitude of neighborhood effects across individual cognitive domains and whether the strength of these associations differs by individual-level factors. The current study investigated these questions in a community sample of older adults ( = 166, mean age = 72.5 years, 51% women), who reported current addresses, linked to state-level Area Deprivation Index rankings, and completed remote and validated neuropsychological tests of verbal intelligence (North American Adult Reading Test), verbal fluency (Controlled Oral Word Association Test), attention (Digit Span Forward), and working memory (Digit Span Backward and Sequencing, Letter-Number Sequencing). Linear regressions tested associations between neighborhood disadvantage and each cognitive test, controlling for individual-level factors (age, sex, education). Exploratory analyses tested moderation by each individual-level factor. Independent of individual-level factors, greater neighborhood disadvantage was associated with lower cognitive performance across domains: verbal intelligence (β = 0.30,  < .001), verbal fluency (β = -0.19,  = .014), attention (β = -0.19,  = .024), and two of three tests of working memory (β = -0.17- -0.22, = .004-.039). Results were robust to correction for multiple comparisons and tests of spatial autocorrelation. In addition, higher neighborhood disadvantage was associated with lower verbal fluency for older - but not younger-older adults ( = .035) and with poorer working memory in women but not men ( < .001). Education did not moderate associations. Findings suggest that older adults living in more disadvantaged neighborhoods exhibit lower cognitive performance, particularly in the domain of verbal intelligence. Continued investigation of effect modification may be fruitful for uncovering for whom associations are strongest.

Aim was to investigate to what extent cognitive functioning differs by three socioeconomic conditions: low income, being without employment, and living alone. A total of N = 158,144 participants of the population-based German National Cohort (NAKO) provided data on socioeconomic conditions and completed cognitive tests. Multivariable confounder-adjusted regression analyses indicated that cognitive functioning was lower in those with low income (b = -0.21) compared to not having low income, living alone (b = -0.04) compared to not living alone, and being without employment (b = -0.09) compared to being employed. An interaction with age indicated that the difference in cognitive functioning was getting larger with age between the income groups and living alone status groups. Accordingly, the three conditions appear independently associated with poorer cognitive functioning. Pathways of how cognitive health in this population group can be improved need to be explored.

Word fluency (WF) tasks that tap verbal and executive function show deteriorating performance by advancing age. To address the scarcely studied age-related brain correlates of WF, we employed whole-brain voxel-based morphometry to examine gray matter (GM) correlates of semantic and phonemic WF in 46 healthy older adults. Lower phonemic WF score was related to smaller anterior medial temporal GM volume as well as smaller GM volume in the putamen bilaterally. A disproportionally weak score on phonemic WF in relation to semantic WF was associated with smaller GM volume in the left inferior frontal cortex, the right anterior medial temporal lobe, and the right striatum. There were no significant associations for semantic WF. The fact that our temporal and subcortical findings were bilateral and right-lateralized, may reflect age-related compensation by these brain areas.

Exercise training has been proposed to counteract age-related cognitive decline through improvements in cardiorespiratory fitness (CRF hypothesis). Research has focused on cognitive domains like attention and processing speed, and one cross-sectional study reported a positive relationship between CRF and language production in older adults. In a randomized controlled trial, we investigated whether these benefits could extend to language comprehension in healthy older adults, and whether bilinguals, for whom language processing is more costly, would exhibit greater benefits than monolinguals. Eighty older English monolinguals and 80 older Norwegian-English bilinguals were randomized into either a 6-month exercise training group or into a passive control group. We assessed CRF (VO2) and language comprehension (reaction times to spoken word monitoring) in first (L1, all participants) and second language (L2, bilinguals only), before and after the intervention. We found that monolinguals in the exercise group (compared to the control group) were faster in comprehension following the intervention. Moreover, this effect was mediated by exercise-induced increases in VO2, supporting the CRF hypothesis. This extends previous cross-sectional research and establishes a causal link between exercise training and speeded comprehension in older monolinguals. However, despite inducing increased VO2, exercise training did not affect bilingual (L1 or L2) comprehension, and bilinguals in both groups were slower after the intervention period. Exploratory analyses suggested that this slowing may be driven by participants with low L2 proficiency, but further research is needed to examine whether bilingual language processing is in fact unaffected by exercise training and its consequent improvements in CRF.

Many older adults report subjective cognitive decline (SCD); however, the specific types of complaints most strongly associated with early disease detection remain unclear. This study examines which complaints from the Everyday Cognition Scales (ECog) are associated with progression from normal cognition to mild cognitive impairment (MCI)/dementia. 415 older adults were monitored annually for 5 years, on average. Cox proportional hazards models assessed associations between ECog complaints and progression to MCI/dementia. Follow-up models included depression as a covariate. Numerous Memory (5 items), Language (3 items), Visuospatial (1 item), Planning (2 items), and Organization (1 item) complaints were associated with diagnostic progression. After covarying for depression, remembering appointments and understanding spoken instructions remained significant predictors of diagnostic progression. While previous work has focused largely on memory-based SCD complaints, the current findings support a wider assessment of complaints may be useful in identifying those at risk for a neurodegenerative disease.

Individuals with amnestic mild cognitive impairment (aMCI), a prodromal stage of Alzheimer's disease and other dementias, show inhibition deficits in addition to episodic memory. How the latent processes of selective attention (i.e., from perception to motor response) contribute to these inhibition deficits remains unclear. Therefore, the present study examined contributions of selective attention to aMCI-related inhibition deficits using computational modeling of attentional dynamics. Two models of selective attention - the dual-stage two-phase model and the shrinking spotlight model - were fitted to individual participant data from a flanker task completed by 34 individuals with single-domain aMCI (sdaMCI, 66-86 years), 20 individuals with multiple-domain aMCI (mdaMCI, 68-88 years), and 52 healthy controls (64-88 years). Findings showed greater commission errors in the mdaMCI group compared to controls. Final-fitting model parameters indicated inhibitory and early perceptual deficits in mdaMCI , and impaired spatial allocation of attention in both MCI groups. Model parameters differentiated mdaMCI from sdaMCI and controls with moderate-to-high sensitivity and specificity. Impairments in perception and selective attention may contribute to inhibition deficits in both aMCI subtypes.

As we age, learning new knowledge and skills becomes more difficult due to age-related changes to cognition. Learning collaboratively could counteract these changes, and perhaps more so when working with someone familiar. This study examined whether collaborative learning is affected by age and partner familiarity. Forty-eight participants (younger  = 24, older  = 24) completed the Map Task with a familiar and unfamiliar same-age partner. Participants became more efficient at completing the Map Task over time, regardless of age and partner familiarity. There was no age difference in immediate or 1-hour recall, but younger adults recalled more after 7 days than older adults. Overall, results suggest that collaborative learning outcomes are unaffected by age or partner familiarity and that collaborative learning has short-term protective effects on memory, with age-related declines only emerging after 7 days.

Emotional reactivity, based on the discrete emotions approach (DEA), is related to opportunities or constraints across development. While prior research suggests sadness to be more adaptive in old age and anger to be more adaptive in young adulthood, there may be facets within these discrete emotion categories that further expand the DEA framework: loss-based vs. failure-based sadness and frustration-based vs. moral violation-based anger. A sample of 49 younger adults ( = 20.00,  = 2.26) and 51 older adults ( = 66.00,  = 4.94) were asked to relive and describe an emotional memory associated with facets of sadness and anger. Emotional reactivity was operationalized through self-report ratings on distinct facet categories. Results revealed a significant age difference in emotional reactivity to moral violation-based anger, with older adults being more reactive than younger adults. No other significant age differences were observed. These findings are discussed in terms of how further distinctions across emotional facets can inform a better understanding of affective experience across adulthood and old age.

Creative divergent thinking involves the generation of unique ideas by pulling from semantic memory stores and exercising cognitive flexibility to shape these memories into something new. Although cognitive abilities decline with age, semantic memory tends to remain intact. This study aims to utilize that memory to investigate the effectiveness of a brief cognitive training to improve creative divergent thinking. Older adults were trained using a semantic retrieval strategy to improve creativity in the Alternate Uses Task (AUT) and the Divergent Association Task (DAT). Participants were tested on the AUT and DAT across three time points: before the strategy was introduced (T0 and T1) and afterward (T2). Results showed that the strategy enhances idea novelty in the AUT; additionally, participants that initially scored lowest on the AUT showed the greatest increase in AUT performance. This finding suggests that older adults can use a semantic retrieval strategy to enhance creative divergent thinking.

The Test of Practical Judgment (TOP-J) has not been thoroughly investigated in terms of its incremental validity. In the current study, we explored whether the TOP-J adds unique and meaningful information to the neuropsychological assessment beyond other executive functioning tests that are often used as proxies for practical judgment. Ninety-seven older adults who were classified as cognitively unimpaired, with subjective cognitive decline, or with mild cognitive impairment completed a comprehensive neuropsychological evaluation. Incremental validity was assessed through hierarchical ordinal regression analysis by modeling the TOP-J (Forms A and B, 15-item and 9-item versions), in addition to widely used tests of executive function, with participant classification/diagnosis as the outcome. The addition of the TOP-J (both 15-item versions) added incremental validity beyond traditional executive functioning measures to predict diagnosis. Including the TOP-J within neuropsychological evaluations of older adults may enhance differentiation of preclinical dementia diagnoses and provide clinically valuable information to the exam.

We tested the longitudinal associations between life space mobility (LSM) at baseline and cognitive performance in three domains (memory, reasoning, and speed of processing) over time. Our analytic sample includes 2,690 older adults (mean age = 73.0, 75.9% female) participating in the ACTIVE Study. We used multiple linear mixed-effects models to evaluate whether LSM, measured using the Life Space Questionnaire, at baseline was longitudinally associated with scores on eight cognitive tests and three composite scores across 10 years. In unadjusted models, there were significant main effects of baseline LSM on memory and reasoning domains, and one speed of processing test (beta: 0.019 to 0.055,  < 0.05). All effects were non-significant in adjusted models. Over time, baseline LSM was associated with one memory test score in adjusted models. Greater LSM at baseline is associated with marginally higher cognitive performance but does not appear to affect the rate of cognitive change at a clinically significant level.

Increased variability in cognitive scores, mood or personality traits can be indicative of underlying neurological disorders. Whether variability in cognition is due to changes in mood or personality is unknown. A total of 66 younger adults, 51 healthy older adults and 38 participants with cognitive impairment completed 21 daily sessions of attention, working memory, mood, and personality assessment. Group differences in mean performance and variability were examined using Bayesian mixed effects location scale models. Variability in attention decreased from younger to older adults and then increased again in cognitive impairment. Younger adults were more variable in agreeableness, openness and conscientiousness compared to older adults. The clinically impaired group differed from the healthy older adults in terms of variability on attention, openness, and conscientiousness. Healthy aging results in greater stability in personality traits over short intervals yet this stability is not redundant with increased stability in cognitive scores.

Remembering our decisions is crucial - it allows us to learn from past mistakes and construct future behavior. However, it is unclear if age-related memory declines impact the memorability of older adults' decisions. Here, we compared younger and older adults' ability to remember their decisions. In Studies 1 and 2, participants made choices between two objects based on their star rating (shopping context) or circle count (neutral context) and later remembered what they chose. while Study 3 tested participants' memory for active vs. passive decisions. Overall, we found no evidence for age differences in the ability to remember decisions. Furthermore, age did not interact with context - both similarly benefitted from making and remembering their decisions in a more shopping-like context. These results reveal an aspect of cognition that appears to be preserved in healthy aging. Highlighting such aspects can help improve older adults' self-perceptions and reframe the narrative around aging.

Reasoning can be fast, automatic, and intuitive or slow, deliberate, and analytical. Use of one cognitive reasoning style over the other has broad implications for beliefs, but differences in cognitive style have not previously been reported in those with mild cognitive impairment (MCI). Here, the cognitive reflection test is used to measure cognitive style in healthy older adults and those with MCI. Those with MCI performed worse than cognitively healthy older adults, indicating they are more likely to engage in intuitive thinking than age-matched adults. This association is reliable after controlling for additional cognitive, self-report, and demographic factors. Across all measures, subjective cognitive decline was the best predictor of cognitive status. A difference in cognitive style represents a novel behavioral marker of MCI, and future work should explore whether this explains a broader pattern of reasoning errors in those with MCI, such as susceptibility to scams or impaired financial reasoning.

Aging can impact emotional recognition, affecting older adults' mental health and social function. This study examined how aging affects affective prosody comprehension (APC: understanding emotions through speech) across seven emotions (happiness, surprise, sadness, anger, fear, disgust, and neutrality) and its relationship with cognitive function (via the Montreal Cognitive Assessment) and social support (via the Social Support Rating Scale) in 199 cognitively normal older adults. We found that older adults had lower APC accuracy and more errors, often mistaking negative emotions for neutral or positive ones. APC accuracy was significantly associated with social support, and a partial least squares (PLS) cognitive component fully mediated the relationship between the APC component and social support utilization, explaining 61.7% of the total effect. These results suggest that declines in APC during aging are linked to social support utilization through cognitive function, offering insights for interventions to improve social and cognitive health in older adults.

Estrogen exposure during menstrual years has been associated with late-life neuroprotection. We explored the presence of an age-sensitive menarche window for cognition in old age and the impact of socioeconomic status and education. We compared neuropsychological performance of 1082 older women [Mean = 72.69 (5.48)] with menarche in childhood, early-, mid-, and late-adolescence and dementia prevalence, severity, and type, including the effects of education and socioeconomic status. Adjusting for covariates, menarche at 11-14 years of age was associated with better memory, executive and global cognitive functioning in old age, and stronger positive effects of education and socioeconomic status on cognition than those with menarche at 15-17 years. We found a critical age window for the neuroprotective effects of estrogens during early adolescence, putting women with later menarche at higher risk for cognitive decline. Effects of socioeconomic status and education in adulthood should be a focus of future research.

This study investigated the impact of language learning in comparison to other complex learning activities on cognitive functioning and psychosocial well-being in cognitively healthy, community-dwelling older adults. In a randomized controlled trial, 43 Dutch functionally monolinguals aged 65-78 completed a three-month English course ( = 15), music training ( = 13), or a lecture series ( = 15). Cognitive functioning (global cognition, cognitive flexibility, episodic memory, working memory, verbal fluency, and attention) and psychosocial well-being were assessed before and immediately after the intervention, and at a four-month follow-up. The language learners significantly improved on episodic memory and cognitive flexibility. However, the magnitude of cognitive change did not significantly differ between the language learning and music training conditions, except for a larger positive change in cognitive flexibility for the language learners from pretest to follow-up. Our results suggest that language learning in later life can improve some cognitive functions and fluency in the additional language, but that its unique effects seem limited.

Navigational abilities decline with age, but the cognitive underpinnings of this cognitive decline remain partially understood. Navigation is guided by landmarks and self-motion cues, that we address when estimating our location. These sources of spatial information are often associated with noise and uncertainty, thus posing a challenge during navigation. To overcome this challenge, humans and other species rely on navigational cues according to their reliability: reliable cues are highly weighted and therefore strongly influence our spatial behavior, compared to less reliable ones. We hypothesize that older adults do not efficiently weigh spatial cues, and accordingly, the reliability levels of navigational cues may not modulate their spatial behavior, as with younger adults. To test this, younger and older adults performed a virtual navigational task, subject to modified reliability of landmarks and self-motion cues. The findings revealed that while increased reliability of spatial cues improved navigational performance across both age groups, older adults exhibited diminished sensitivity to changes in landmark reliability. The findings demonstrate a cognitive mechanism that could lead to impaired navigation abilities in older adults.

Having a sense of purpose in life predicts better maintenance of cognitive function in older adulthood and reduced risk of mild cognitive impairment (MCI) and dementia. However, little research has examined its influence on the rate of cognitive decline and length of cognitive healthspan. This study evaluated the role of sense of purpose on the risk and timing of transitions between normal cognition, MCI, and dementia. Older adults from the Memory and Aging Project (MAP;  = 1821) and the Health and Retirement Study (HRS;  = 10,542) were followed annually for 19 years and biennially for 12 years, respectively. Multistate survival models assessed whether sense of purpose predicted transitions across normal cognition, MCI, dementia, and death. More purposeful older adults had lower risk of developing MCI ( = 0.82 in MAP;  = 0.93 in HRS), higher likelihood of cognitive improvement, and longer cognitively healthy life expectancies. Results suggest sense of purpose may extend the cognitive healthspan.

Aging is associated with cognitive changes, even in the absence of brain pathology. This study aimed to determine if meditation training, by comparison to active and passive control groups, is linked to changes in the perception of cognitive functioning in older adults. One hundred thirty-four healthy older participants from the Age-Well Randomized Clinical Trial were included: 45 followed a meditation training, 45 a non-native language training and 44 had no intervention. Subjective cognition was assessed at baseline and following the 18-month intervention period. Perception of attentional efficiency was assessed using internal and external Attentional Style Questionnaire (ASQ) subscale scores. Perception of global cognitive capacities was measured via the total score of Cognitive Difficulties Scale (CDS). Deltas ([posttest minus pretest scores]/standard deviation at pretest) were calculated for the analyses. Generalized mixed effects models controlling for age, sex, education and baseline scores revealed that meditation training decreased the vulnerability score toward external distractors measured by the ASQ compared to non-native language training. However, no between-groups differences on ASQ internal or CDS total scores were observed. Results suggest a beneficial effect of meditation practice on perceived management of external distracting information in daily life. Meditation training may cultivate the ability to focus on specific information (e.g., breath) and ignore stimulation from other kinds of stimuli (e.g., noise).