Journal of Oral & Facial Pain and Headache

Clinical Handbook for Oral, Facial, and Head Pain
Huff KD and Benoliel R
Discovery of Biomarkers for Myogenous Temporomandibular Disorders Through Salivary Metabolomic Profiling: A Pilot Study
Khoo SC, Shoji Y, Teh CH and Ma NL
To develop a new approach to provide insights into contributing factors to the etiology and pathogenesis of temporomandibular disorders (TMDs) through discrimination of the salivary metabolomic profiling of patients with TMDs of muscular origin (ie, local myalgia) and healthy individuals.
The Physical Symptom Scale-8: Psychometric Characteristics of a Short-Form Version of the PHQ-15 and its Use in TMD-Related Assessment and Research
Yap AU, Lee DZR and Tan SHX
To describe the development of the Physical Symptom Scale-8 (PSS-8) and to examine its psychometric properties and use in temporomandibular disorder (TMD)-related assessment and research.
Letter to the Editor: Evaluation of Facial Pain with Magnetic Resonance Imaging Neurography of the Trigeminal Nerve
Loureiro RM, Sumi DV, Chambi HLV and Soares CR
Abstract Review: Currents in Dental Sleep Medicine
Bailey D and Kato T
Associations Between Temporomandibular Pain and Biobehavioral Variables in Dental Students in Response to an External Stressor
Somoskövi I, Radnai M, Ohrbach R, Dergez T, Tiringer I, Radácsi A and Nagy Á
To assess changes in temporomandibular disorder (TMD) pain and multiple biobehavioral variables relevant to TMDs in response to an external stressor.
Temporomandibular Disorders and Fibromyalgia Prevalence: A Systematic Review and Meta-Analysis
Yakkaphan P, Smith JG, Chana P, Tan HL, Ravindranath PT, Lambru G and Renton T
To evaluate the prevalence of chronic widespread pain (CWP) and fibromyalgia syndrome (FMS) in TMD patients and the prevalence of TMDs in patients with FMS.
Practitioner/Practice- and Patient-Based Factors Contributing to Dental Practitioner Treatment Recommendations for Patients with Pain-Related TMDs: Findings from the National Dental PBRN
Riley JLI, Rindal DB, Velly AM, Anderson GC, Johnson KS, Gilbert GH, Schiffman EL and
To document National Dental Practice-Based Research Network (PBRN) practitioner treatment recommendations for patients with painful temporomandibular disorders (TMDs) and to identify practitioner/practice- and patient-related factors contributing to treatment recommendations made at the initial clinical visit.
Editorial: Chronic Orofacial Pain in Older Adults
Eliav E and Arany S
No summary.
Overtreatment "Successes"--What Are the Negative Consequences for Patients, Dentists, and the Profession?
Greene CS and Manfredini D
To describe how some management practices in the field of orofacial musculoskeletal disorders (also described as temporomandibular disorders [TMDs]) are based on concepts about occlusal relationships, condyle positions, or functional guidance; for some patients, these procedures may be producing successful outcomes in terms of symptom reduction, but in many cases, they can be examples of unnecessary overtreatment.
Temporomandibular Disorders as Contributors to Primary Headaches: A Systematic Review
Dibello V, Lozupone M, Sardone R, Ballini A, Lafornara D, Dibello A, Vertucci V, Santarcangelo F, Maiorano G, Stallone R, Petruzzi M, Daniele A, Solfrizzi V and Panza F
To systematically review the literature assessing associations between TMDs and primary headaches.
Manual Therapy Applied to the Cervial Joint Reduces Pain and Improves Jaw Function in Individuals with Temporomandibular Disorders: A Systematic Review on Manual Therapy for Orofacial Disorders
Liberato FM, da Silva TV, Santuzzi CH, Ferreira Fachini de Oliveira N and Nascimento LR
To examine the effect of manual therapy applied to the cervical joint for reducing pain and improving mouth opening and jaw function in people with TMDs.
Investigation of Factors Associated with Dizziness, Tinnitus, and Ear Fullness in Patients with Temporomandibular Disorders
Karacay BC and Korkmaz MD
To determine differences between TMD subtypes in terms of clinical characteristics, dizziness, tinnitus, and ear fullness according to the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) and to investigate the clinical conditions associated with dizziness, tinnitus, and ear fullness. Participants having TMDs aged 18 to 45 years were included in this study. They were classified and divided into three groups according to the DC/TMD Axis I criteria: group 1 = pain-related TMDs and headache; group 2 = intra-articular joint disorders; and group 3 = degenerative joint disease. Demographic data and dizziness, tinnitus, and ear fullness were assessed. Maximum mouth opening, opening/closing click, lateral click, fine/coarse crepitation, bruxism, and presence of pain were evaluated by physical examination. A total of 129 participants were included: 68 (52.7%) in group 1, 40 (31%) in group 2, and 21 (16.3%) in group 3. In the comparison of all three diagnostic groups, there was a significant difference only in educational level ( = .013). The presence of dizziness, tinnitus, or ear fullness was not found to be significantly different among the three groups. When all participants were divided into two groups according to the presence of dizziness, low education levels ( = .007), being married ( = .040), presence of pain ( = .002), tinnitus ( = .008), ear fullness ( = .017), and presence of thin crepitation ( = .015) were related to having dizziness symptoms. In addition, patients with ear fullness ( = .042), dizziness ( = .008), and female sex ( = .008) reported more tinnitus. TMD subtype was not associated with dizziness, tinnitus, or ear fullness. Painful conditions were associated with dizziness in participants with TMDs.
Catastrophizing and Hypervigilance Influence Subjective Sleep Quality in Painful TMD Patients
Poluha RL, Canales GT, Ferreira DM, Stuginski-Barbosa J and Conti PCR
To determine sleep quality and associated factors in a group of patients with painful TMDs. The medical records of 80 patients with arthralgia and/or myofascial pain were reviewed and compared to a healthy control group. Data about sex, age, subjective pain, physical activity, social activity, subjective sleep quality (Pittsburgh Sleep Quality Index [PSQI]), pain vigilance (Pain Vigilance and Awareness Questionnaire [PVAQ]), and pain catastrophizing (Pain Catastrophizing Scale [PCS]) were collected. Relationships between PSQI, age, pain intensity, PVAQ, and PCS in the TMD group were also analyzed. Data from the control group were used to transform the PSQI results into T-scores, which were then used to divide the TMD group into two subgroups: normal and impaired sleep. TMD patients presented a significantly higher ( < .001) PSQI score than the control group. Also, in the TMD group, there was a low to moderate correlation between PSQI and pain intensity and a significant correlation between PVAQ and PCS. The impaired sleep group presented a significantly higher ( < .001) PSQI T-score than the normal sleep group. Univariate analysis showed that subjective pain, social activity, and the PCS total and subscale scores differed significantly between the different PSQI T-score groups. The comparison between TMD pain patients and control subjects showed a significantly higher prevalence of T-score discordance in almost all PSQI components in TMD patients with impaired sleep. Subjective sleep quality in painful TMD patients could be associated with and influenced by psychosocial factors (catastrophizing and hypervigilance), social activity, and pain intensity.
Recommendations for Imaging of the Temporomandibular Joint. Position Statement from the American Academy of Oral and Maxillofacial Radiology and the American Academy of Orofacial Pain
Mallya SM, Ahmad M, Cohen JR, Kaspo G and Ramesh A
This position statement was developed by an ad hoc committee of the American Academy of Oral and Maxillofacial Radiology and the American Academy of Orofacial Pain. The committee reviewed the pertinent literature and drafted recommendations for imaging. This joint statement provides evidence-based recommendations and clinical guidance for applying appropriate diagnostic imaging to evaluate the temporomandibular joint (TMJ). This manuscript guides the design of TMJ imaging examinations, addresses in-office CBCT imaging, and provides timely evidence-based recommendations to evaluate the TMJ bony components, also addressing the use of MRI and other modalities to evaluate TMJ involvement in different pathologic conditions.
A Meta-Synthesis of the Experience of Chronic Temporomandibular Disorder Patients Within Health Care Services
Taimeh D, Leeson R, Fedele S and Riordain RN
To systematically review the qualitative evidence related to experiences of patients with temporomandibular disorders (TMD) and to explore their journeys within health care services. A systematic search of the following databases was conducted: MEDLINE, Embase, PsycINFO, Web of Science, CINAHL Complete, and the Cochrane database. Thematic synthesis was used to analyze and synthesize the data from qualitative studies that explored the journeys of TMD patients within health care services. The Critical Appraisal Skills Programme (CASP) tool was used to critically appraise the quality of the included studies. The search strategies yielded 4,563 articles across all databases, and 18 articles were eventually included. Six themes were derived: care-seeking attitudes; expectations and health care experience; the patient-clinician interaction; diagnosis as a stepping stone for improvement; management; and social support. The journey within health care services may play a valuable role in the ability to cope with chronic TMDs. Receiving a diagnosis, being listened to, and being believed are among the most important elements making for a positive clinical experience.
Neural Correlates of Tooth Clenching in Patients with Bruxism and Temporomandibular Disorder-Related Pain
Kluskens TJ, Kessler PA, Jansma BM, Kaas A and van de Ven V
To measure brain activity in patients with bruxism and temporomandibular disorder (TMD)-related pain in comparison to controls using functional magnetic resonance imaging (fMRI) and to investigate whether modulations in jaw clenching led to different pain reports and/or changes in neural activity in motor and pain processing areas within and between both groups.
Novel Migraine Treatments: A Review
George N and Tepper SJ
To present a review of the mechanisms of action, available clinical data, and safety profiles of novel migraine therapeutics to inform practice. PubMed, Medline, and Google Scholar were searched for randomized controlled trials (24 publications), review articles (15 publications), and other pertinent literature (16 publications) discussing the novel migraine therapeutics available between the years 2010 and 2021. All publications were reviewed to assess the mechanism of action, relevant clinical data, and side effect profile for each novel treatment. Therapeutic gain was also recorded in studies that included a placebo arm. A total of 55 studies were included in the final analysis. In the preventive treatment of migraine, novel medications target calcitonin gene-related peptide (CGRP) and fall into either the monoclonal anti-CGRP or gepant class. For the acute treatment of migraine, novel medications fall into either the ditan or gepant class. Several medical devices have been developed for the acute and preventive treatment of migraine. Novel therapeutics are available for both the prevention and acute treatment of migraine headaches. These new medications and neuromodulatory devices appear overall to be safe and effective in the management of migraine headaches.
A Controlled Study of Biopsychosocial Differences Observed in Masticatory Myalgia With and Without Pain Referral
Varun S, Anderson GC, Hodges JS, Zhang L and Schiffman EL
To assess differences in biopsychosocial factors between participants with masticatory myofascial pain with referral (MFPwR), with myalgia without referral (Mw/oR), and community controls without TMDs.
Differential Item Functioning of the Jaw Functional Limitation Scale
Pattanaik S, John MT, Chung S and Keller S
To assess the differential item functioning (DIF) of the Jaw Functional Limitation Scale (JFLS) due to gender, age, and language (English vs Spanish).
Patient-Reported Outcome Measures Used in Temporomandibular Disorders: A Review of the Literature
Taimeh D, Ni Riordain R, Fedele S and Leeson R
To identify the range of patient-reported outcome measures (PROMs) used in TMD studies, summarize the available evidence for their psychometric properties, and provide guidance for the selection of such measures.