Laryngoscope Investigative Otolaryngology

Reflux disease and congenital laryngomalacia in neonates: A Kids' Inpatient Database analysis
Shah VP, Patel AM, Kaki PC, Yassa A and Filimonov A
Congenital laryngomalacia (CLM) is the most common cause of stridor in neonates and is commonly associated with reflux disease (RD) such as gastroesophageal reflux and newborn esophageal reflux. This study investigates the impact of RD on the management and outcomes of neonates with CLM.
Individualized post-operative prediction of cochlear implantation outcomes in children with prelingual deafness using functional near-infrared spectroscopy
Chen Z, Zhao X, Liu H, Wang Y, Zhang Z, Zhang Y and Liu Y
The goal of this study was to develop an objective measure and predictor of cochlear implantation (CI) outcomes using functional near-infrared spectroscopy (fNIRS) for young children with prelingual deafness.
Parotid sialolithiasis - Long term follow-up analyzing surgical approaches
Tanenbaum Z, Wenzel P, Molotkova E, Fick B, Henkle K and Hoffman H
Present follow-up data comparing transoral and transfacial parotid gland procedures for stone removal to offer insight addressing technical considerations and complications.
Causes and treatment of secondary sphenoid sinus infection post-endoscopic transsphenoidal approach
Dong Y, Zhou B, Cui S, Huang Q, Sun Y, Huang Z, Ma J, Yang Q and Liang N
This study analyzed the causes of sphenoid sinus (SS) infection (SSI) following endoscopic transsphenoidal skull base surgery and determined appropriate treatment methods.
Prognosis of asymptomatic endolymphatic hydrops in healthy volunteers: A five-year cohort study
Kimura T, Kitahara T, Okayasu T, Sakagami M, Shiozaki T, Inui H, Koizumi T and Kakudo M
This study aimed to clarify the prognosis of asymptomatic endolymphatic hydrops (EH) in healthy volunteers via five-year follow-ups with inner ear magnetic resonance imaging (MRI).
Effect of betahistine on pro-inflammatory cytokine expression in autoimmune inner ear disease and Meniere's disease patients
Yellin I, Pathak S and Vambutas A
Betahistine is a partial H1 receptor agonist and a potent H3 receptor antagonist commonly used for the treatment of MD and peripheral vertigo. The aim of this study was to investigate the impact of betahistine on the salt induced cytokine expression profiles of AIED and MD patients.
Automated classification of online reviews of otolaryngologists
Stenzel JG, Schultz NR and Marino MJ
The study aimed to extract online comments of otolaryngologists in the 20 most populated cities in the United States from healthgrades.com, develop and validate a natural language processing (NLP) logistic regression algorithm for automated text classification of reviews into 10 categories, and compare 1- and 5-star reviews in directly-physician-related and non-physician-related categories.
Challenges and outcomes of airway surgery in a post-war low-resource setting: A case series from Mekelle, Ethiopia
Eyassu DG, Candelo E, Asgedom BH, Wallerius KP, Twardus SW, Niermeyer WL, Green KJ, Athni TS and Wiedermann JP
This study aims to document and analyze the challenges and outcomes of performing complex airway surgery in a low-resource, post-war setting in Mekelle, Ethiopia.
Perilymphatic enhancement and endolymphatic hydrops: MRI findings and clinical associations
Kobayashi M, Yoshida T, Fukunaga Y, Hara D, Naganawa S and Sone M
In this study, we aimed to summarize magnetic resonance imaging (MRI) findings of perilymphatic enhancement (PE) and endolymphatic hydrops (EH) of the inner ear, which are associated with vestibular and cochlear symptoms.
Impact of implementing stricter criteria for blood transfusion in patients with head and neck cancer undergoing free tissue transfer
Hamdi OA, Danan D, Denner A, Bellinger JR, Thornton N, Shonka DC, Garneau JC, Fedder K, Jameson MJ and Dowling EM
Recent literature studying the impact of blood transfusion on outcomes in patients with head and neck cancer (HNC) have shown that blood transfusions are associated with increased risk of death and higher wound infection rates. The purpose of this study was to implement a lower transfusion threshold while comparing outcomes of free flap patients following initiation of a new transfusion guideline.
The pathophysiology of dysphagia post-lung transplant: A systematic review
Smaoui S, Cummins E, Mena M, Scott S and Tobar-Fredes R
One major consequence of lung transplantation is the development of oropharyngeal dysphagia. This systematic review aims to appraise and synthesize the available evidence of the use of instrumental assessments to outline the characteristics of post-lung transplant dysphagia.
3D reconstruction of vocal fold dynamics with laser high-speed videoendoscopy in children
Patel RR, Döllinger M and Semmler M
The objective of this study is to evaluate three-dimensional vertical motion of the superior surface of the vocal folds in vivo in (a) typically developing children as a function of vocal frequency variations and (b) a child with vocal nodules.
Outpatient management of pediatric epistaxis: A cost analysis and clinical model
Lee JA, Puchi C, Billings KR, Lavin JM, Hazkani I, Glennon C, Thompson DM and Maddalozzo J
Pediatric epistaxis is a common, often non-operative condition encountered by Otolaryngologists. The present study seeks to (1) describe our outcomes of epistaxis management, (2) estimate the associated healthcare burden, and (3) propose a clinical model to optimize care coordination with primary care and advanced practice providers.
Reply to "Letter to the Editor: Salivary gland ultrasound elastography requires interpretation of 'normal'"
Chang CF and Wang HK
Salivary gland ultrasound elastography requires interpretation of "normal"
Hoffman HT, Wenzel P, Zenk J, Marcelino A and Quon H
Immunocytochemistry assessment of vocal fold regeneration after cell-based implant in rabbits
Nicolas L, Mandl H, Schrader F and Long JL
Cell-based outer vocal fold replacement (COVR) offers a potential treatment for severe vocal fold scarring or cancer reconstruction. Previous work in rabbits using human adipose-derived stem cells (ASC) in fibrin suggested that a hybrid structure emerged within 2 months, containing both implanted and host cells. This project uses immunocytochemistry to better define the phenotypic fate of implanted cells and features of the extracellular environment.
Comprehensive evaluation of deep neck infections: A retrospective analysis of 111 cases
Aksoy A, Demirkıran BB, Bora A, Doğan M and Altuntaş EE
Our study will analyze patients' clinical characteristics, treatment strategies, and complications with deep neck infection (DNI) using their medical records for five years.
Current approaches to facial nerve schwannoma surgery
Hernandez-Montero E, Garcia-Ibañez L, Jubes S, Salmeron J, Garcia-Ibañez E and Larrosa F
Facial nerve schwannomas (FNSs) are exceedingly rare benign tumors. This study aims to report on a series of excised FNSs, providing clinical information and details on their surgical management, including novel approaches.
otitis externa: A retrospective study of predisposing factors, treatment, and complications
Viljanen M, Saarinen R and Hafrén L
To study the predisposing factors, treatment, and complications of otitis externa.
A MAUDE database analysis on the new generation of active bone conduction hearing implants
Lein A, Baumgartner WD, Landegger LD, Riss D, Thurner T, Liu DT, Kosec A, Vyskocil E and Brkic FF
To analyze medical device reports (MDR) submitted to the Food and Drug Administration's (FDA) Manufacturer and User Device Facility Experience (MAUDE) database to identify adverse events (AEs) in patients implanted with novel active bone conduction hearing implants (BCIs).
Surgical resection and overall survival in cT4b sinonasal non-squamous cell carcinoma
Patel AM, Haleem A, Revercomb L, Brant JA, Kohanski MA, Adappa ND, Palmer JN, Douglas JE and Carey RM
Surgical resection is associated with higher overall survival (OS) than definitive radiotherapy (RT) or chemoradiotherapy (CRT) in cT4b sinonasal squamous cell carcinoma (SCC). Our study investigates the survival benefit of surgical resection in cT4b sinonasal non-SCC.