ARCHIVES OF DISEASE IN CHILDHOOD

Exploring interaction effects of social determinants of health with hospital admission type on academic performance: a data linkage study
Dipnall JF, Lyons J, Lyons R, Ameratunga S, Brussoni M, Rivara FP, Lecky F, Schneeberg A, Harrison JE and Gabbe BJ
To investigate the moderating effects of socio-demographic social determinants of health (SDH) in the relationship between types of childhood hospitalisation (ie, none, injury, non-injury, injury+non-injury) and academic performance.
Graves' disease: are we just delaying the inevitable?
Stevens C, Langham S, Amin R, Dattani M, Brain C and Peters C
Towards evidence-based medicine for paediatricians
Phillips B
Short-term weight variability in infants and toddlers: an observational study
Wright CM, Hope-McGill F, Sivakanthan H and Cole TJ
To explore short-term weight variability in young children; (1) how it relates to expected weight gain and (2) how it is affected by age, time of day and dietary intakes and outputs.
Are virtual wards for children safe and effective? A 3-year retrospective service evaluation of an urban Hospital at Home service for children and young people
Cheung CR, Farnham L, Al-Mukhtar R, Chahal A, Karcz K, Nagano C and Abraham B
Service evaluation of an urban 'Hospital at Home' service which provides care in patients' homes that would traditionally be delivered in the hospital setting.
Incidence of sudden unexplained death in childhood for children aged 1-14 years in England and Wales during 2001-2020: an observational study
Garstang JJ, Tosyali M, Menka M and Blair PS
The objective is to determine the incidence of sudden unexplained death in childhood (SUDC) for children aged 1-14 years in England and Wales during 2001-2020.
Therapeutic privilege
Wheeler R
Time to take it 'out' side: delabelling allergy to penicillin and other beta-lactams in children and young people
Turner P
Holistic, codesigned skin control programme for impetigo; true patient and public involvement
Highlights from the literature
Compatibility of pentoxifylline injection with syringe and inline filters
De Silva DTN, Strunk T, Petrovski M, Mukadam N and Batty KT
Codesign and evaluation of advanced therapeutic information resources for and with families of children with neurological conditions: a mixed methods cross-sectional study
Meagher CE, Kariyawasam DS, Concepcion KAE, Dale R, Hetherington K, Mohammad S, Palmer EE, Woolfenden S and Farrar MA
Parents and caregivers of children with neurological conditions express interest in new and developing treatments and trials; however, they have limited knowledge of, and access to, reliable information. This study aims to empower and equip decision-making and support communication in the application of advanced neurotherapeutics and personalised medicine, covering gene therapy, stem cell therapy, neurostimulation and neuroimmunotherapies.
Triage tools in the paediatric emergency department
Systematic review of interventions to reduce hospital and emergency department stay in paediatric populations
Dick S, MacRae C, Colacino L, Wilson P and Turner SW
This systemic review describes interventions designed to shorten length of stay (LOS) in hospital or the emergency department (ED).
Predictive performance of cerebrospinal fluid parameters for diagnosis of meningitis in infants: a cohort study
O'Leary C, Pittet LF, Beaumont R, Constable L, Daley A, Hodge I, Jacobs SE, King A, Tan C, Curtis N and Gwee A
The gold standard for diagnosis of meningitis is the isolation of a pathogen from cerebrospinal fluid (CSF) by culture or PCR. However, treatment is routinely commenced based on CSF findings prior to microbiological results. This study determined the predictive value of CSF parameters for diagnosing bacterial and viral meningitis in young infants.
Effectiveness of paediatric asthma hubs: a clinical pilot study
Hakizimana A, Lo DKH, Roland D, Rai VK, Danvers L, Rowlands R, Ahmed MI, Herzallah R and Gaillard EA
Children and young people (CYP) with asthma in the UK are at higher risk of poor outcomes compared with other high-income European countries due to factors including poor access to high-quality asthma reviews, diagnostic testing and inconsistent postattack reviews. The Leicester Integrated Care Board funded the first UK pilot asthma hub for CYP, to investigate the feasibility and effectiveness of hubs, in providing postattack reviews along with providing asthma education, the opportunity to carry out diagnostic lung function tests and optimise treatment.
Should next-generation sequencing be considered as a first-line genetic investigation for children with early developmental impairment?
Sarantis F, Guobadia AO, Bebars MA, Varma R, Holland JAA and Ratnaike T
Case of sapphire eyes with hearing loss: Waardenburg syndrome type 1 in a young girl
Gaurav V, Lalmuanpuii G, Gowda P and Guglani A
Complications of excess weight seen in two tier 3 paediatric weight management services: an observational study
Hawton K, Apperley L, Parkinson J, Owens M, Semple C, Canvin L, Holt A, Easter S, Clark K, Lund K, Clarke E, O'Brien J, Giri D, Senniappan S and Shield JPH
Children and young people living with severe obesity experience a range of complications of excess weight (CEW); however the prevalence of complications is not well defined. We have evaluated baseline characteristics and CEW of patients from two UK tier 3 paediatric weight management services.
Cascade testing effectively identifies undiagnosed sickle cell disease in The Gambia: a quality improvement project
Deans-Louis E, Allen A and Allen SJ
Sickle cell disease (SCD) has a high mortality during childhood in many low and middle-income countries (LMICs). Early diagnosis improves outcomes but newborn screening is not well established in LMICs. Cascade testing may be feasible and effective in identifying undiagnosed SCD and carriers of haemoglobin (Hb) S.
Hospital-recorded chronic health conditions in children with and without Down syndrome in England: a national cohort of births from 2003 to 2019
Shumway J, Ellis J, Stephens A, De Stavola BL, Gilbert R and Zylbersztejn A
The objective is to describe age-specific cumulative incidence for hospital-recorded indicators of chronic health conditions (CHCs) in children with Down syndrome (DS) compared with children without DS.