JOURNAL OF RHEUMATOLOGY

Ringing in the Patient Voice: Measuring Patients' Lived Experience of Dermatomyositis Symptoms
Ardalan K and Rider LG
The development and validation of measures of disease activity, damage, and health-related quality of life (HRQOL) over the past 30 years has been fundamental in advancing research and care for patients with adult and juvenile idiopathic inflammatory myopathies (IIMs). These efforts have resulted in the development of core set measures of disease activity and damage for myositis, and the American College of Rheumatology (ACR)/European Alliance of Associations for Rheumatology (EULAR)-endorsed Myositis Response Criteria, which have been successfully implemented in IIM clinical trials and which recently facilitated the US Food and Drug Administration licensure of intravenous immunoglobulin for dermatomyositis (DM)..
Disparities in time to diagnosis of Radiographic Axial Spondyloarthritis
Ferrandiz-Espadin R, Rabasa G, Gasman S, McGinley B, Stovall R, Jafarzadeh SR, Liew JW and Dubreuil M
Radiographic axial spondyloarthritis (r-axSpA) has a 7-year average diagnostic delay. While the impact of sex or gender on time to diagnosis has been evaluated, the role of social determinants of health remains understudied. We assessed whether time from initial clinical documentation of r-axSpA symptoms to r-axSpA diagnosis (diagnostic delay) varies based on sex, race, ethnicity, or the presence of social needs.
Obese Patients With Polymyalgia Rheumatica Experience More Pain And Disability At Disease Onset And Require Higher Doses Of Glucocorticoids
Cimmino MA, Crowson CS, Dasgupta B, Schirmer M, Dejaco C, Salvarani C, Matteson EL and Camellino D
polymyalgia rheumatica (PMR) is an inflammatory disorder of the elderly characterized by girdle pain and stiffness. Obesity has an influence on disease activity and outcome in rheumatic diseases like osteoarthritis and rheumatoid arthritis, but its relationship to the severity and outcome of PMR is unknown.
Hydrocephalus-Related Dementia in Paget Disease of the Skull
Carvalho JDF and Romeu JC
Paget disease of bone (PDB) is a chronic skeletal disorder caused by abnormal bone remodeling. Although neurological complications are uncommon, they may arise in advanced cases, particularly with skull involvement.
A Stratification Approach Based on Salivary Gland Ultrasonography for Assessing Secretory Function in Sjögren's Disease
Huang W, Hao S, Ouyang Z, Peng L, Chen X, Yang W, Zhong W, Chen J, Dai L and Mo Y
Our aim was to develop an ultrasonographic scoring model for staging hypofunction of salivary gland (SG) in patients suffering from Sjögren's disease (SjD).
Introducing "Rheumatology Around the World"
Silverman ED
Broadening the Landscape for Treatment Recommendations in the Management of Axial Spondyloarthritis
Bautista-Molano W
Tocilizumab for Giant Cell Arteritis: Clinical Outcomes Following Relapses and Tocilizumab Discontinuation Due to Adverse Events
Nagase FN, Fukui S, Takizawa N, Yamaguchi T, Oda N, Inokuchi H, Ito T, Watanabe M, Suda M, Haji Y, Suyama Y, Rokutanda R, Minoda M, Nomura A, Uechi E and Tamaki H
Tocilizumab (TCZ) is effective for giant cell arteritis (GCA). However, little is known regarding treatment modification and clinical outcomes after unfavorable events, such as GCA relapses or TCZ discontinuation due to adverse events (AEs).
Cardiovascular Health and Adverse Pregnancy Outcomes in Autoimmune Rheumatic Diseases
Parimi VP and Ravindran V
Radiographic Axial Spondyloarthritis (Ankylosing Spondylitis) Commencing Late in Life
Hwang MC, Doughem K, Lee M, Gensler LS, Ishimori ML, Ward MM, Brown MA, Tahanan A, Weisman MH, Rahbar MH and Reveille JD
Large Language Models in Rheumatologic Diagnosis: A Multimodal Performance Analysis
Omar M, Agbareia R, Klang E and Naffaa ME
The evaluation of myocarditis in patients with Still's disease; clinical findings from the multicentre international AIDA Network Still's Disease Registry
Ruscitti P, Di Cola I, Vitale A, Caggiano V, Palumbo P, Di Cesare E, Torres-Ruiz J, Guaracha-Basañez GA, Martín-Nares E, Ciccia F, Iacono D, Riccio F, Maggio MC, Tharwat S, Hashad S, Rigante D, Ortolan A, Giardini HAM, Parente de Brito Antonelli I, Cordeiro RA, Giacomelli R, Navarini L, Berardicurti O, Conforti A, Opris-Belinski D, Sota J, Gaggiano C, Lopalco G, Iannone F, La Torre F, Mastrorilli V, Govoni M, Ruffilli F, Emmi G, Biancalana E, Sfikakis PP, Tektonidou M, Hernández-Rodríguez J, Gómez-Caverzaschi V, Gündüz ÖS, Conti G, Patroniti S, Gidaro A, Bartoli A, Olivieri AN, Gicchino MF, Brucato AL, Dagna L, Tomelleri A, Campochiaro C, De Paulis A, Mormile I, Della Casa F, Direskeneli H, Alibaz-Oner F, Karamanakos A, Dimouli A, Ragab G, Mahmoud Ahmed AA, Tufan A, Kucuk H, Kardas R, Batu ED, Ozen S, Wiesik-Szewczyk E, Hinojosa-Azaola A, Balistreri A, Fabiani C, Frediani B and Cantarini L
To evaluate the cardiac involvement in patients with Still's disease with a focus on myocarditis included in the multicenter AIDA (AutoInflammatory Disease Alliance) network Still's disease registry. To exploit the predictive factors for myocarditis in deriving a clinical risk patient profile for this severe manifestation.
Pursuing Gender Equity in Rheumatology: Thinking Beyond Gender Representation to Assess Gender Equality
Ross L, Bond S and Day JA
Association of Past Smoking Status With Gout in Māori People in Aotearoa New Zealand
Fanning NC, Pearson JF, Dalbeth N, Watson H, Merriman TR and Stamp LK
Evidence for an association of smoking with gout is conflicting. We assessed associations of current and past smoking with gout in an Aotearoa New Zealand (NZ) population.
Mucosa-Associated Lymphoid Tissue Lymphoma as a Rare Mimicker of Relapsing Polychondritis
Tada N, Oguro N and Yajima N
Mucosa-associated lymphoid tissue (MALT) lymphoma is a low-grade B cell extranodal lymphoma characterized by clonal marginal zone lymphocyte proliferation. We report a case of MALT lymphoma with a relapsing polychondritis (RP)-like phenotype, manifesting as rapidly progressive tracheal stenosis requiring tracheotomy.
Infected Tumoral Calcinosis Associated With Rheumatoid Arthritis
Sugawara E, Ninagawa K and Katsumata K
Tumoral calcinosis (TC) is a syndrome of unknown etiology characterized by calcium salt deposition in soft tissues. A case of infected TC with rheumatoid arthritis (RA) is described.
Incidence of Pneumocystis jirovecii Pneumonia and Prophylaxis-Associated Adverse Events Among Patients with Systemic Lupus Erythematosus
Jiang Y, Duarte-García A, Putman M and Gazeley D
Pneumocystis jirovecii Pneumonia (PJP) is an opportunistic infection that may affect patients with systemic lupus erythematosus (SLE). The objective of this project was to describe the incidence of PJP among patients with SLE.
The Lived Experiences of Older Adults with Systemic Lupus Erythematosus: Patient Perspectives
Lieber SB, Young SR, Shea Y, Gottesman SP, Lipschultz R, Sun D, Reid MC, Mandl LA and Navarro-Millán I
Little is known about perceptions of aging among individuals living with systemic lupus erythematosus (SLE). Gaining this knowledge could help to identify targets for future behavioral interventions aimed at successful aging with SLE. This qualitative study sought to elicit the lived experiences, and essence, of aging from older adults with SLE.
Patient profiles in randomised controlled trials versus a real-world study, in psoriatic arthritis: scoping review and meta-analysis
Alle G, Lopez-Medina C, Siebert S, Lavie F, Noel W, Smolen JS and Gossec L
Patients with psoriatic arthritis (PsA) in randomised controlled trials (RCTs) may not reflect patients in clinical practice. The objective was to perform a meta-analysis of PsA patients' characteristics in RCTs of biologic disease-modifying antirheumatic drugs (bDMARDs), and to compare them to patient profiles in a real-world study.
Prologue: Spondyloarthritis Unmet Research Needs Conference IV
Colbert RA, Carroll E, Dubreuil M, Gensler LS, Haroon N, Howard R, Ogdie AR, Shafer C, Weiss PF and Kuhn KA
The Spondylitis Association of America (SAA) and the National Institute of Arthritis, Musculoskeletal and Skin Diseases (NIAMS) convened a conference on the campus of the National Institutes of Health (NIH) on September 28 and 29, 2023, to identify unmet needs in spondyloarthritis (SpA) research. The conference featured presentations by experts in areas of disease endotypes, pain, innovative imaging in SpA, health disparities in rheumatic diseases, and therapeutics. Members of the conference planning committee moderated the sessions and led the development of manuscripts summarizing recommendations to address unmet research needs. Early career investigators were invited to submit abstracts, which were presented at a networking session during the conference. Here, we highlight each of the sessions comprising the conference in the form of manuscripts published together as a conference summary.
Unmet Needs in Spondyloarthritis: Understanding and Managing Chronic Pain
Lee YC, Malfait AM and Ogdie AR
Among patients with axial spondyloarthritis (axSpA), persistent pain remains a critical unmet need. In this review, we discuss the prevalence of chronic pain and fibromyalgia in patients with axSpA and examine the existing knowledge on the pathophysiology of chronic pain in SpA, osteoarthritis, and rheumatoid arthritis. Finally, we discuss the specific unmet needs that must be addressed to improve long-term outcomes in axSpA, specifically those that will improve chronic pain in this patient population.