Quantitatively assessing the impact of the quality of SNOMED CT subtype hierarchy on cohort queries
SNOMED CT provides a standardized terminology for clinical concepts, allowing cohort queries over heterogeneous clinical data including Electronic Health Records (EHRs). While it is intuitive that missing and inaccurate subtype (or is-a) relations in SNOMED CT reduce the recall and precision of cohort queries, the extent of these impacts has not been formally assessed. This study fills this gap by developing quantitative metrics to measure these impacts and performing statistical analysis on their significance.
Linking national primary care electronic health records to individual records from the U.S. Census Bureau's American Community Survey: evaluating the likelihood of linkage based on patient health
To evaluate the likelihood of linking electronic health records (EHRs) to restricted individual-level American Community Survey (ACS) data based on patient health condition.
Machine learning-based infection diagnostic and prognostic models in post-acute care settings: a systematic review
This study aims to (1) review machine learning (ML)-based models for early infection diagnostic and prognosis prediction in post-acute care (PAC) settings, (2) identify key risk predictors influencing infection-related outcomes, and (3) examine the quality and limitations of these models.
Mini-mental status examination phenotyping for Alzheimer's disease patients using both structured and narrative electronic health record features
This study aims to automate the prediction of Mini-Mental State Examination (MMSE) scores, a widely adopted standard for cognitive assessment in patients with Alzheimer's disease, using natural language processing (NLP) and machine learning (ML) on structured and unstructured EHR data.
Correction to: Artificial intelligence for optimizing recruitment and retention in clinical trials: a scoping review
Using human factors methods to mitigate bias in artificial intelligence-based clinical decision support
To highlight the often overlooked role of user interface (UI) design in mitigating bias in artificial intelligence (AI)-based clinical decision support (CDS).
Research for all: building a diverse researcher community for the All of Us Research Program
The NIH All of Us Research Program (All of Us) is engaging a diverse community of more than 10 000 registered researchers using a robust engagement ecosystem model. We describe strategies used to build an ecosystem that attracts and supports a diverse and inclusive researcher community to use the All of Us dataset and provide metrics on All of Us researcher usage growth.
The role of routine and structured social needs data collection in improving care in US hospitals
To understand how health-related social needs (HRSN) data are collected at US hospitals and implications for use.
Efficacy of the mLab App: a randomized clinical trial for increasing HIV testing uptake using mobile technology
To determine the efficacy of the mLab App, a mobile-delivered HIV prevention intervention to increase HIV self-testing in MSM and TGW.
Machine learning-based prediction models in medical decision-making in kidney disease: patient, caregiver, and clinician perspectives on trust and appropriate use
This study aims to improve the ethical use of machine learning (ML)-based clinical prediction models (CPMs) in shared decision-making for patients with kidney failure on dialysis. We explore factors that inform acceptability, interpretability, and implementation of ML-based CPMs among multiple constituent groups.
DySurv: dynamic deep learning model for survival analysis with conditional variational inference
Machine learning applications for longitudinal electronic health records often forecast the risk of events at fixed time points, whereas survival analysis achieves dynamic risk prediction by estimating time-to-event distributions. Here, we propose a novel conditional variational autoencoder-based method, DySurv, which uses a combination of static and longitudinal measurements from electronic health records to estimate the individual risk of death dynamically.
Identifying stigmatizing and positive/preferred language in obstetric clinical notes using natural language processing
To identify stigmatizing language in obstetric clinical notes using natural language processing (NLP).
Distributed, immutable, and transparent biomedical limited data set request management on multi-capacity network
Our study aimed to expedite data sharing requests of Limited Data Sets (LDS) through the development of a streamlined platform that allows distributed, immutable management of network activities, provides transparent and intuitive auditing of data access history, and systematically evaluated it on a multi-capacity network setting for meaningful efficiency metrics.
Evaluating gradient-based explanation methods for neural network ECG analysis using heatmaps
Evaluate popular explanation methods using heatmap visualizations to explain the predictions of deep neural networks for electrocardiogram (ECG) analysis and provide recommendations for selection of explanations methods.
Learning health system linchpins: information exchange and a common data model
To demonstrate the potential for a centrally managed health information exchange standardized to a common data model (HIE-CDM) to facilitate semantic data flow needed to support a learning health system (LHS).
Trending in the right direction: critical access hospitals increased adoption of advanced electronic health record functions from 2018 to 2023
We analyzed trends in adoption of advanced patient engagement and clinical data analytics functionalities among critical access hospitals (CAHs) and non-CAHs to assess how historical gaps have changed.
Oncointerpreter.ai enables interactive, personalized summarization of cancer diagnostics data
Cancer diagnosis comes as a shock to many patients, and many of them feel unprepared to handle the complexity of the life-changing event, understand technicalities of the diagnostic reports, and fully engage with the clinical team regarding the personalized clinical decision-making.
Is ChatGPT worthy enough for provisioning clinical decision support?
Comparison of six natural language processing approaches to assessing firearm access in Veterans Health Administration electronic health records
Access to firearms is associated with increased suicide risk. Our aim was to develop a natural language processing approach to characterizing firearm access in clinical records.
Predicting mortality in hospitalized influenza patients: integration of deep learning-based chest X-ray severity score (FluDeep-XR) and clinical variables
To pioneer the first artificial intelligence system integrating radiological and objective clinical data, simulating the clinical reasoning process, for the early prediction of high-risk influenza patients.
A machine learning framework to adjust for learning effects in medical device safety evaluation
Traditional methods for medical device post-market surveillance often fail to accurately account for operator learning effects, leading to biased assessments of device safety. These methods struggle with non-linearity, complex learning curves, and time-varying covariates, such as physician experience. To address these limitations, we sought to develop a machine learning (ML) framework to detect and adjust for operator learning effects.