This was an original research. The objective of the study was to investigate the efficacy of laparoscopic type C radical hysterectomy by deep uterine vein approach in treating cervical cancer. Two hundred cases of cervical cancer were allocated into control group and intervention group. The control group underwent pelvic lymph node dissection + para-aortic lymph node resection followed by extensive hysterectomy. The intervention group underwent laparoscopic type C radical hysterectomy by deep uterine vein approach + pelvic lymph node dissection ± para-aortic lymph node resection. In comparison with the control group, the intervention group had significantly lower amount of blood loss, longer time of indwelling catheter, shorter time of abdominal drainage tube removal and anal exhaust, lower incidence of postoperative complications, higher rate of pathological stage upgrading, and higher quality of life score, and had lower recurrence rate. We conclude that laparoscopic C-type radical hysterectomy by deep uterine vein approach is effective, safe and reliable, and can promote patients quality of life, which is valuable for clinical use.

This was a randomised controlled study to investigate the effect of web-based breastfeeding education given to primiparous pregnant women on postpartum breastfeeding. The study included a total of 120 primiparous pregnant women, including control group (n:60) and experimental group (n:60). The study was conducted in a district in northern Turkey. Only the pregnant women in the experimental group received web-based breastfeeding education. Descriptive statistics and independent two-sample t-test analysis were used to analyse the data and to compare the demographic characteristics and scale scores according to the groups. 'IOWA Infant Feeding Scale', "Edinburgh Depression Scale", "IMDAT", "Breastfeeding Self-Efficacy Scale", "Perception of Insufficient Milk Scale" and "Breastfeeding Motivation Scale" were administered to the experimental and control groups on the 7th day, 3rd month and 6th month after birth. Several factors, including breastfeeding motivation, breastfeeding self-efficacy, and the perception of milk sufficiency for the baby, were significantly different between the groups (p<0.001). A significant difference was found between the two groups in terms of mothers breastfeeding their babies within the first half hour after birth. All of the mothers in the experimental group breastfed their babies within the first half hour. Breastfeeding self-efficacy and motivation levels in the experimental group showed a statistically significant increase when compared to both pre-training levels and the control group. (Clinical Trials Number: NCT06443801).

Anaemia is a common phenomenon in patients with malignant gynecological tumors. The occurrence of anaemia in the perioperative period leads to an increased probability of blood transfusion, increased surgical complications,poor wound healing, prolonged hospitalization, increased medical costs, and increased mortality. Intravenous iron, which is known for its rapid onset and lack of gastrointestinal side effects, has become increasingly prevalent in clinical practice. A total of 300 patients with gynaecological malignancies were admitted to The First Affiliated Hospital,Hengyang Medical School,University of South China between January, 2019 and December , 2021. Anaemia was assessed during routine blood tests by measuring red blood cell (RBC) counts, hemoglobin (Hb) levels, haematocrit (HCT) values, mean corpuscular volume (MCV), and mean corpuscular hemoglobin (MCH). The postoperative blood transfusion rate, transfusion volume, infection rate, and hospitalization duration were also recorded and comparisons were made between the control and treatment groups.Our study showed that preoperative intravenous iron injection can effectively increase haemoglobin levels in patients with anemia caused by gynecological cancer, reduces the probability of perioperative blood transfusion., decreases postoperative complications and infection rates, shortens hospital stays, and improves short-term prognosis in patients. We concluded that intravenous iron presents is a valuable clinical option for addressing perioperative anaemia in patients with gynecologic malignancies.

Elevated serum uric acid (SUA) levels in pregnancy are linked to adverse outcomes, including preterm birth, preeclampsia, and low birth weight. To assess the predictive value of SUA levels in early pregnancy for adverse pregnancy outcomes (APOs). A cohort of 4,240 pregnant women admitted for delivery from January 2021 to December 2022 was analyzed. APOs were compared between women with hyperuricemia (HUA) (UA > 360 μmol/L) and those without HUA. Logistic regression (LR) analysis was used to identify risk factors for APOs. Among the cohort, 295 women (6.9%) had HUA. Compared to the non-HUA group, the HUA group had a higher BMI (22.45 vs. 21.34), higher rates of hypertension (6.1% vs. 3.4%), preterm birth (10.2% vs. 6.3%), and low birth weight (10.2% vs. 5.9%). Multivariate LR analysis identified elevated UA levels, BMI, diabetes, and preeclampsia as significant risk factors for APOs. The optimal UA threshold for predicting preterm birth was 253.855 μmol/L (sensitivity: 71.4%, specificity: 55.2%). Early pregnancy SUA levels are predictive of adverse pregnancy outcomes, providing a foundation for potential clinical interventions. Given the moderate sensitivity and specificity of the identified SUA threshold for predicting preterm birth, further research is warranted to refine these values and establish their clinical implications in obstetric practice.

It is sometimes said that when America sneezes, the world catches a cold. The opposite scenario may also apply: a healthy and progressive American economy and democracy provides needed resources and hope to many parts of the world, including Africa. Four years ago, we wrote an optimistic message in this journal.2,3 We asserted that newly-minted President Joseph Biden would reinstate and strengthen Obama-era global health programs that former President Donald Trump stripped and defunded during his four-year term. These programs included support for combatting and preventing HIV/AIDS, tuberculosis, malaria, reproductive health, and infectious disease research.

The current study aims to determine how the interactions between practice (distributed/focused) and mental capacity (high/low) in the cloud-computing environment (CCE) affect the development of reproductive health skills and cognitive absorption. The study employed an experimental design, and it included a categorical variable for mental capacity (low/high) and an independent variable with two types of activities (distributed/focused). The research sample consisted of 240 students from the College of Science and College of Applied Medical Sciences at the University of Hail's. The sample was divided into four experimental groups. The study's most significant findings were the CCE's apparent favoritism of the group that studied using focused practice style and high mental capacity in the reproductive health skills test, as opposed to distributed practice style and low mental capacity in cognitive absorption. The findings will add to the ongoing debate over which of the two distributed/focused practice activity models is more effective in achieving desired educational results.

This study investigated the professional values of midwifery students and the factors influencing these values. Conducted from January 6 to March 6, 2021, it involved 715 midwifery students who participated voluntarily. Data was collected using a Descriptive Data Sheet and the Professional Values of Midwives Scale. Statistical analysis included descriptive statistics, two-way ANOVA, Independent Samples T Test, and Bonferroni Correction. The mean age of participants was 20.63 years; 99.2% were single, and 29.7% were second-year students. Participants mostly graduated from the following schools to Anatolian high schools (57.5%) and predominantly lived in cities (55.1%), with 81.1% from nuclear families. A significant number of parents had a primary education (mothers: 50.8%, fathers: 35.4%). The mean score on the Professional Values of Midwives Scale was high. Significant differences in scores were noted based on age, high school type, long-term residence, family type, parental education, and interest in midwifery. However, the difference was not significant found. related to academic year, willingness to choose midwifery, preference ranking, self-suitability for the profession, or shifts in perspective before and after education. These findings emphasize the multifaceted nature of professional values in midwifery students and the various factors shaping their attitudes.

This study was an original article, mainly aimed to explore the influence of nutritional guidance during pregnancy on nutritional status and pregnancy outcome of pregnant women. Two hundred (200) pregnant women were admitted to the Nanjing General Hospital of Nanjing Military Command from May 2021 to May 2023. They were randomly sub-divided into a control group and an intervention group. Each group had 100 cases. The control group received routine guidance, while the intervention group received personalized nutrition guidance based on standards from the routine guidance protocol. The results showed that in comparison with the control group, the intervention group presented higher calcium, protein, folate, sodium, iron, vitamin and zinc levels, lower fat levels, lower incidence of adverse birth outcomes, lower incidence of adverse neonatal status, higher fetal body weight and Apgar score higher satisfaction rate, and lower incidence of complications during pregnancy. We conclude that reasonable intake of nutrition during pregnancy can meet the nutritional needs of pregnant women and fetuses, improve pregnancy safety, improve delivery and newborn conditions, reduce the occurrence of pregnancy complications, and improve the satisfaction of pregnant women.

The study was designed to appraise the effects of early antibiotic administration on reproductive tract infections and fetal membrane cell scorching in instances of premature rupture of membranes (PROM). A total of 107 pregnant women diagnosed with PROM between July 2020 and June 2022 were randomly assigned to two groups: the Intervention (n=54), where ampicillin were administered within 24 hours of PROM onset, and the control group (n=53), where ampicillin were given 24-48 hours after PROM. Maternal and neonatal outcomes, incidence of reproductive tract infections, and fetal membrane cell scorching indicators (Caspase-1, Caspase -3, Caspase-9 and IL-β) were compared. The intervention group had significantly fewer adverse maternal and neonatal outcomes (p<0.05). Post-treatment, rates of Chlamydia trachomatis, Mycoplasma solium, and genital tract infections decreased in both groups, with lower rates in the intervention group (p<0.05). Positive expression rates of Caspase-1, -3, -9, and IL-β in placental tissues were also lower in the intervention group (p<0.05). We conclude that administering antibiotics within 12 hours of PROM reduces reproductive tract infections, lowers fetal membrane cell scorching, and improves maternal and neonatal outcomes, supporting early antibiotic use in the management of PROM.

Through implementing a bidirectional Mendelian randomization (MR) study, the causal effects between gut microbiome and polycystic ovary syndrome (PCOS) were analyzed. Summary statistics for PCOS were acquired from the FinnGen consortium R8 release data, which included 27,943 cases and 162,936 controls. The inverse-variance weighting (IVW) method was adopted for analysis. Additionally, the causality involving exposure plus the outcome was evaluated by means of MR-Egger, weighted median, simple mode methods, as well as weighted mode. The IVW estimate showed that the genera Streptococcus plus Enterorhabdus served as protectors of PCOS. By contrast, the phylum Tenericutes, genera Anaerofilum, Coprococcus 2, Lachnospiraceae ND3007 group and Ruminiclostridium 5 were identified as risk elements of PCOS. Based on reverse MR analyses from PCOS on the intestinal microbiome based on the IVW method, the phyla Tenericutes, Actinobacteria, class Actinobacteria, genera Ruminococcaceae UCG004 and Christensenellaceae R 7group exhibited a down-regulation effect after PCOS onset. The genera Bacteroides, Barnesiella, Erysipelotrichaceae UCG003, Ruminococcus gnavus group, and Veillonella were up-regulated. No horizontal pleiotropy or significant IV heterogeneity was observed. We conclude that there is a causality relationship between gut microbiome and PCOS, where some bacterial taxa can be used as biomarkers to promote targeted diagnosis and therapy for PCOS.

With 25% of teenagers pregnant by age of 19 and about half of these married before their 18th birth day, Uganda exhibits one of the highest rates of teenage pregnancy and child marriage globally. Comprehensive data on the drivers and barriers to addressing repeat teenage pregnancies and early child marriages remains limited. Using the narrative inquiry approach, the paper explores the key socio-cultural drivers and barriers to addressing repeat teenage pregnancies and early/forced marriages among stakeholders in the districts of Mbale, Kween, Namayingo and Kalangala. Guided by purposive sampling, a total of 125 qualitative interviews (80 key informant interviews (KIIs) and 45 focus group discussions (FGDs) were conducted. Data analysis was done using deductive thematic analysis in Atlas ti software. The drives of repeat teenage pregnancy (RPT) include the distorted community understanding of repeat teenage pregnancy; poverty at the household; norms, traditions and beliefs; cultural and traditional practices; lack of comprehensive sex education, school dropout, Peer pressure and influence, and vulnerable populations. The results point to a strong relationship between teenage pregnancy, early child/forced marriage and repeat teenage pregnancy across all the four districts and to poverty as the driving force.

This study examined the effects of a combination of plan-do-check-action (PDCA) and enhanced recovery after surgery (ERAS) on patients undergoing cesarean section. One hundred and thirty patients undergoing caesarean section at the Second Affiliated Hospital of Nantong University comprised the study group. They were randomly divided into a control group (CG) and an intervention group (IG). The CG accepted routine management during the perioperative period, while the IG accepted a combination nursing of PDCA and ERAS. Relative to the CG, the IG presented lower visual analogue scale (VAS) scores at 4 h and 72 h after cesarean section, lower self-rating anxiety scale (SAS) scores and self-rating depression scale (SDS) scores, shorter time of anal exhaust, first urination along after leaving bed, lower total incidence rate of complications, and higher satisfaction rate of patients. We conclude that a combination nursing of PDCA and ERAS can alleviate postoperative pain, improve the psychological state, expedite postoperative recovery along with lessen the incidence of complications in patients undergoing cesarean section.

Folic acid (FA) plays a crucial role in various biological processes. Insufficient intake of FA during pregnancy can lead to serious clinical complications, including neural tube defect. The current study sought to assess the awareness, knowledge, and usage of FA among young females in Jazan region of Saudi Arabia. This cross-sectional descriptive study involved 472 adult females from October 1 to 9, 2023, in Jazan region, Saudi Arabia. The questionnaire of the study was randomly distributed among females. The data showed that awareness and usage of FA supplementation were poor to fair among females. Furthermore, socio-demographic variables, including age, marital status, monthly income, education levels, number of pregnancies, and current pregnancy status, were found to be associated with awareness and utilization of FA supplementation. The study highlights the need to enhance awareness and knowledge of FA supplementation among females in the Jazan region. Introducing educational programs is essential in Saudi Arabia, particularly in the Jazan region, to enhance the knowledge and awareness of FA within the community.

Nursing interventions play a critical role in enhancing the quality of life (QoL) and therapeutic outcomes for cervical cancer patients undergoing chemotherapy. However, variations in nursing interventions and patient results require a meta-analysis to consolidate evidence on the most effective nursing approaches. This meta-analysis assessed how nursing care interventions influence QoL, adherence to chemotherapy, and the management of symptoms in cervical cancer patients. An extensive search through PubMed, Web of Science, and Cochrane Library databases yielded 17 randomized controlled trials (RCTs) that met the eligibility requirements. The findings revealed that nursing interventions significantly boosted QoL (OR = 1.28, 95% CI: 1.10 to 1.49), increased adherence to chemotherapy protocols (OR = 1.35, 95% CI: 1.15 to 1.60), and alleviated chemotherapy-induced symptoms like fatigue and nausea (OR = 1.42, 95% CI: 1.20 to 1.67). Funnel plots showed minimal publication bias in the studies analyzed. We conclude that nursing interventions significantly enhance QoL, treatment adherence, and symptom control for cervical cancer patients undergoing chemotherapy.

Giant ovarian cysts (GOCs) have become less common in developed countries due to routine health screenings, but they remain prevalent in economically underdeveloped regions. Treatment options for GOCs depend on factors such as age, cyst characteristics, and pregnancy status. Minimally invasive single-port laparoscopic surgery has largely replaced traditional open surgery due to its aesthetic advantages and effectiveness. In this case series, six patients with giant ovarian cysts, including two pregnant women, underwent single-port laparoscopic surgery. The procedure was aimed to reduce scarring, ensure safety, and preserve fertility. Strict criteria were used to rule out malignancy and assess suitability for the minimally invasive approach. Five patients had successful surgeries with positive cosmetic outcomes, while one required conversion to a mini-laparotomy due to technical difficulties. Postoperative recovery was smooth, with patients expressing satisfaction with the aesthetic results. This study demonstrates that single-port laparoscopic surgery is a safe and effective method for treating large ovarian cysts, combining the advantages of traditional laparoscopy with enhanced cosmetic results. The approach is particularly beneficial for younger and pregnant patients, with careful timing of surgery recommended to minimize pregnancy-related risks.

The discharge time of the postpartum woman is an issue related to emotional readiness and hospital policies and should be evaluated by the nurse. The feeling of readiness of the postpartum woman is the key in making the decision to discharge.The objective of the study is to evaluate the discharge readiness of puerperium and to determine the factors affecting.This study included 323 postpartum women who visited the obstetrics and gynecology outpatient clinic of the hospital between Semtember 10, 2021, and January 31, 2022, and met the inclusion criteria. Data were collected using the Personal and Obstetric Information form, The Readiness for Hospital Discharge Scale-Postpartum Mother Form(RHDS-PM). The chi-square test, Fisher's exact test, and the Fisher-Freeman-Halton test were used in the comparison of categorical data. Categorical data are presented as frequencies and percentages The mean age of the participants was 28.57±5.69 years. In our study, it was found that the mean RHDS-PMF score of the postpartum women was 154.29±31.08. A statistically significant difference was found in satisfaction with nursing care based on postpartum knowledge status (p< 0.001).Based on this study's results, the average discharge scale score of the postpartum women in the group was determined to be ready. The scale score of those who believe that they would be capable of self-care at home is higher than those who do not. Thus, the education and the self care power provided support postpartum women's satisfaction with nursing care and their readiness for discharge.

This study sought to compare bacterial abundance and diversity in milk and feces of healthy lactating women with patients suffering from lactation mastitis, explore the pathogenesis of lactation mastitis, and develop new ideas for its treatment and prevention from a microbiological perspective. A total of 19 lactating mastitis patients and 19 healthy lactating women were recruited. Milk and fecal Specimens were obtained from both groups, and microbial community structure was analyzed using 16S rRNA gene sequencing. Our results reveal significant alternations in microbial composition and distribution of milk and feces between healthy lactating women and mastitis patients. The findings suggest that lactating mastitis patients have dysregulated gut and milk microbiota, and modulating the gut-mammary axis may be a potential strategy for preventing or treating mastitis.

Manual vacuum aspiration (MVA) is a painful procedure often conducted without analgesia. The World Health Organization (WHO) recommends a paracervical block (PCB) as the mode of pain relief during MVA. Few studies have assessed patient perspectives on pain control during MVA. We investigated the perspectives of health workers and patients on MVA under PCB. This study was nested within a pilot randomized controlled trial (RCT) evaluating the Chloe SED (syringe extension device) for PCB provision. Eleven providers and 61 patients were enrolled. All providers had MVA experience. They had not provided pain relief on 20% of occasions, and only one had previously administered PCB for MVA. Both patients and providers indicated MVA was painful and deserving of analgesia. Pain was the most common reason for difficulty completing an MVA. Providers noted that PCB made the procedure more tolerable. For patients, efficacy, remaining conscious, and same-day discharge were key considerations when selecting pain relief. Notably, 84% of patients expressed satisfaction with MVA under PCB. PCB is a vital component of the MVA care package. Considering patient and provider perspectives is essential to optimizing a humane and effective procedural experience.

This study assesses gender inequality in education and employment in BRICS (Brazil, Russia, India, China, and South Africa) countries between the 2000 and 2021, using data from the World Bank database. A descriptive data analysis was carried out as well as graphical representations to compare among countries. The results showed that that female education achieved significant success, especially at secondary and tertiary levels, through specific policies including financial support and affirmative actions. Brazil and Russia maintained an increasingly higher enrollment at the secondary level of education. In contrast, China recorded very rapid growth in tertiary enrollments, reaching over 92% enrolment of females. History, poverty, and social pressures were identified as systemic barriers in the enrollment of girls to school in India and South Africa. This study indicate that even when gains are achieved on the educational front, translating them into gains in terms of equality in employment proves difficult. Secondly, the unemployment rates among females in countries such as Brazil and South Africa are higher, reflecting more significant socio-economic problems. This calls for more vigorous policy responses toward gender inequality within the labour market through labour reforms, job creation policies, and specific support to women's employment in the informal sector in the BRICS countries.

This was an original article, and the objective of this study was to investigate the effects of bipolar transurethral plasma kinetic prostatectomy (TUPKP) on urodynamics and sexual function in benign prostatic hyperplasia (BPH) patients. One hundred and four BPH patients were divided into a control group and an intervention group. The control group received transurethral resection of prostate, while the intervention group received TUKEP. Relative to the control group, the intervention group presented less intraoperative blood loss and shorter bladder irrigation time, catheter retention time, and shorter hospital stay. Three months after surgery, the improvements of maximum urine flow rate (Qmax), pressure-flow rate (A-G) and residual urine volume (RV) in intervention group were more obvious than control group. One month after surgery, relative to control group, the intervention group had lower C-reactive protein (CRP), epinephrine (E) along with cortisol (Cor), cyclo-oxygenase 2 (COX-2) and vascular endothelial growth factor (VEGF) levels. On day 7 after surgery, PSA, EGF, and PGE2 levels in the intervention group were lower when compared to the control group. We conclude that TUKEP can diminish intraoperative blood loss, promote postoperative recovery, improve postoperative urodynamics and sexual function, and improve prognosis of BPH patients.

This study evaluated the factors affecting maternal satisfaction during labor and neonatal outcomes. This cross-sectional study was conducted with 319 mothers who gave birth in a hospital (01.10.2023-31.03.2024) and volunteered for the study. Data were collected using a personal information form including socio-demographic and obstetric characteristics of the mothers and the 'Birth Satisfaction Scale'. The mean age of the mothers who participated in the study was 28.07±6.44 years. The mean score of the Birth Satisfaction Scale was 22.29±5.03. The sub-dimensions of the scale were found to be significantly affected by mode of delivery, various factors (p<0.05). Positive birth experience also affects maternal satisfaction. This study showed that maternal satisfaction in labor was at a moderate level. It explains that maternal satisfaction in labor is affected by the mode of delivery and other factors. In addition, it is seen that the method of delivery has various negative effects on the newborn.