PSYCHIATRIC CLINICS OF NORTH AMERICA

A Review of Research on Acceptance and Commitment Therapy for Anxiety and Obsessive-Compulsive and Related Disorders
Twohig MP, Capel LK and Levin ME
This article reviews acceptance and commitment therapy (ACT) for anxiety disorders, obsessive-compulsive disorder (OCD), trichotillomania, excoriation disorder, hoarding, and body dysmorphic disorder (BDD). Measurement of psychological inflexibility and its relationship to pathology is reviewed. Outcome work in all disorders listed is reviewed with results supporting ACT for anxiety disorders, OCD, and trichotillomania, but there is limited evidence for excoriation disorder, hoarding, and BDD. Future research should focus on processes of change in addition to outcomes.
Pharmacotherapy for Anxiety Disorders
O'Leary KB and Khan JS
Anxiety disorders are the most common psychiatric illness and include disorders such as generalized anxiety disorder (GAD), panic disorder (PD), and social anxiety disorder (SAD). Psychotherapy and pharmacotherapy are both effective treatments for anxiety disorders, with efficacy between 60% and 85%. Selective serotonin reuptake inhibitors and serotonin-norepinephrine reuptake inhibitors are first-line pharmacologic treatment for GAD, PD, and SAD. Recommendations for treating pediatric and geriatric populations vary slightly, but first-line treatments remain the same. Recent advancements in the treatment of anxiety disorders are limited although research has discovered novel pathways, which may lead to additional treatment options in the future.
Anxiety Disorders in Later Life
Johnco CJ, Matovic D and Wuthrich VM
Contrary to ageist stereotypes, anxiety disorders are less common in older compared with younger adults. However, anxiety is often under-recognized and undertreated in this population. Anxiety disorders affect around 1 in 10 older adults, are unremitting, and are associated with a range of negative outcomes, including increased risk of depression, cognitive and functional decline, physical health problems, increased healthcare use, and suicide. This article summarizes the epidemiology and risk factors of anxiety in later life, explores variations in symptom presentation compared with younger adults, and outlines recommendations for assessment and treatment.
Childhood Anxiety Disorders
Stiede JT, Mangen KH and Storch EA
Anxiety disorders are common in children and adolescents, with many youths experiencing functional impairment in multiple domains because of these conditions. Biologic and cognitive-behavioral models provide a basis for the development and maintenance of these disorders. Cognitive behavioral therapy (CBT) with exposures and selective serotonin reuptake inhibitors or serotonin and norepinephrine reuptake inhibitors are empirically supported treatments for childhood anxiety disorders. Exposures are a key component of CBT treatment and a case vignette demonstrates how to tailor exposures to the unique fears of the child.
Cultural and Social Aspects of Anxiety Disorders
Holly LE
Understanding the cultural and social aspects of anxiety disorders is necessary to ensure the design and implementation of effective, evidence-based methods for diagnosis, prevention, and treatment among diverse populations, particularly those who are minoritized, marginalized, and traditionally underserved. This article describes variations in anxiety disorder prevalence and the association between sociocultural characteristics and stressors known to increase risk for anxiety. The ways sociocultural context impacts anxiety phenomenology and expression is explored. Then, the literature examining differential help-seeking and service utilization among diverse populations is reviewed followed by a summary of culturally responsive, evidence-based practices for anxiety disorders.
Anxiety Disorders in Autistic People: A Narrative Review
Schiltz HK, McVey AJ and Lord C
Anxiety is the most common co-occurring mental health condition across the lifespan for autistic people. The authors summarize the extant research on prevalence, correlates and predictors, measurement, and treatment of anxiety disorders in autistic people, which has rapidly expanded in the past decade. In addition to addressing gaps within each of these areas, the authors propose that there is a need for future work to center autistic perspectives, employ longitudinal designs, and expand the focus to include autistic adults and those with co-occurring intellectual disability.
Family Factors in the Development and Management of Anxiety Disorders
Treadwell KRH
Theoretic models of anxiety disorders have emphasized the impact of caregiving on the development and maintenance of childhood anxiety. Familial factors demonstrate a reciprocal relationship with child anxiety, including family stressors, parenting control, and family accommodation. The inclusion of parents in intervention for youth anxiety has demonstrated a superior outcome in several studies and is recommended as an area to evaluate when child anxiety is presented for assessment and treatment. This review examines familial variables in their contribution to clinical levels of anxiety in youth, focusing on genetic, family environment, and parental behaviors and recommendations for prevention and treatment intervention.
Brief Interventions for Anxiety
Caporino NE
Brief, nonpharmacological interventions for anxiety are often defined as no more than 10 sessions or 50% contact time of a full intervention. Brief interventions can be of high or low intensity, depending on the type and extent of therapist support provided, and may be concentrated. There is evidence to support the use of brief cognitive-behavioral interventions for anxiety in mental health clinics, primary care, and schools, and internet delivery can be a cost-effective alternative to standard formats. Research to identify cases requiring longer and/or more intense intervention is needed to inform stepped-care approaches to improving treatment access.
Technological Advances in Treating Anxiety Disorders
Goetter EM and Yuen EK
There has been tremendous interest in utilizing digital interventions to assist in the treatment of anxiety disorders. Anxiety disorders are widely prevalent and often characterized by avoidance, intolerance of uncertainty, interpersonal concerns, and worry. Digital mental health interventions, given their flexibility, may be particularly suited to this population. The authors review the literature on the use of videoconference, virtual reality, website self-help, and mobile applications in the treatment of anxiety disorders. Empirical evidence, advantages, and disadvantages of each format are considered. Additionally, we identify clinical and social challenges unique to the use of these technologies for intervention purposes.
Cognitive Behavioral Therapy for Anxiety Disorders
Trent ES and Storch EA
Cognitive behavioral therapy (CBT) is the front-line psychological intervention for the treatment of anxiety disorders. It is based on the cognitive behavioral model of anxiety disorders, which conceptualizes anxiety as caused by a pattern of maladaptive cognitive appraisals and avoidance behaviors that perpetuate pathologic fears. CBT includes core components that are relevant across anxiety disorders, including psychoeducation, cognitive restructuring, exposure therapy, and relapse prevention. CBT has a strong evidence base supporting its short-term and long-term efficacy and effectiveness. A case vignette is provided to illustrate the application of CBT principles. Clinical complexities, clinical recommendations, and future research directions are discussed.
Clinical Considerations for an Evidence-Based Assessment of Anxiety Disorders in Children and Adolescents
Miller ML, Steuber ER and McGuire JF
This article provides an overview of evidence-based assessment (EBA) of anxiety disorders in children and adolescents. First, this article provides an overview of using clinician-rated scales in the diagnostic process. Second, this article reviews the clinical utility of clinician-rated measures, and parent-report and youth-report measures to characterize anxiety severity and monitor treatment response in clinical practice. Additionally, rating scales that capture clinical constructs that are relevant in anxiety disorders-such as accommodation and avoidance behaviors-are succinctly reviewed. Finally, the article concludes with recommendations for conducting an EBA for anxiety disorders in children and adolescents.
Importance of Managing Anxiety Disorders
Stiede JT and Storch EA
Anxiety Disorders
Storch EA
Anxiety Disorders: Diagnoses, Clinical Features, and Epidemiology
Lack CW
Although anxiety disorders present in many ways, they all share the key features of inappropriately high distress in the form of anxiety and fear responses to stimuli that are not actually dangerous and efforts to avoid or escape such stimuli. Problematic levels of fear and anxiety can result in many negative impacts on people's lives, across social, economic, and physical realms. Anxiety disorders as a whole are very prevalent in today's world, among both youth and adults.
Clinical Considerations for an Evidence-Based Assessment of Anxiety Disorders in Adults
Steuber ER, Miller ML and McGuire JF
Evidence-based assessment (EBA) is critical for successful diagnosis and treatment of adult anxiety disorders. First, diagnostic interviews are reviewed with emphasis on how these tools can be used inform clinical diagnoses. Second, clinician-rated measures and self-report scales used to characterize anxiety symptom severity in adults are discussed. Third, to further inform clinical care, rating scales that illustrate clinical profiles contributing to symptom maintenance and severity-namely accommodation and avoidance behaviors-are discussed. Lastly, a summary of recommendations for using EBA for the diagnosis and treatment of anxiety disorders in adults is shared.
Multidimensional Approaches to Quality Measurement and Performance Improvement in the Ideal Crisis System
Hopper K, Pinheiro A, Shoyinka S, Parks J, Minkoff K, Shaw B, Goldman ML and Balfour ME
This work expands on the National Council for Mental Wellbeing whitepaper Quality Measurement in Crisis Services. The authors present 2 approaches to measure development: The first maps flow through the crisis continuum and defines metrics for each step of the process. The second uses the mnemonic ACCESS TO HELP to define system values, from the perspective of various stakeholders, with corresponding metrics. The article also includes case examples and discusses how metrics can align multiple components of a crisis system toward common goals, strategies for using metrics to drive quality improvement initiatives, and the complexities of measuring and interpreting data.
The Journey Toward 988: A Historical Perspective on Crisis Hotlines in the United States
Draper J and McKeon RT
This article reviews the historical trajectory of crisis hotlines in the United States from their 1960's inception as 24/7 alternatives to traditional mental health services to becoming "the front door" of the 988 Suicide and Crisis Lifeline in 2022. The Substance Abuse and Mental Health Services Administration's (SAMHSA's) 2001 effort to network, certify, and evaluate crisis hotlines laid the foundation for demonstrating the efficacy of crisis hotlines and their ability to reduce distress and suicidality in people accessing these services. SAMHSA-funded evaluations and the collective leadership of the National Suicide Prevention Lifeline network established evidence-based standards, policies, and practices.
Community-Based Mental Health Crisis Response: An Overview of Models and Workforce Implications
Compton MT, Pope LG and Watson AC
Communities across the United States are working to improve community-based mental health crisis response, with 1 goal being to reduce criminal legal system involvement among individuals with mental illnesses, behavioral disorders, or mental health crises. Existing and recently developed models can generally be divided into non-law enforcement-based response models and law enforcement-based response models. Wide variation exists in terms of staffing, how response teams are called out or dispatched, hours of operation and immediacy of response, and approaches to crisis resolution.
Crisis Receiving and Stabilization Facilities: Designing Systems for High-Acuity Populations
Balfour ME and Carson CA
Crisis facilities provide a safe and therapeutic alternative to emergency departments and jails for people experiencing behavioral health emergencies. Program design should center around customer needs which include individuals and families in crisis and key community stakeholders like first responders. Ideally, a crisis system should be organized into a broad continuum of services that ensures care is provided in the least restrictive setting, even for people with high acuity needs, and stakeholders should have a clear understanding of the capabilities of each component facility and the population it can safely serve. This paper provides a framework to help policymakers achieve this goal.
Postcrisis Follow-Up and Linkage to Community Services
McClanahan A, Adams CN, Hackman AL, Cotes RO and Minkoff K
During the postcrisis period, many individuals struggle to transition to available care, often falling through the cracks. This article discusses effective postcrisis approaches that provide rapid access to transitional team-based care using critical time intervention strategies. It also highlights the development of state, county, and funder models for "care-traffic control" to ensure swift linkage to follow-up services, along with new funding models that support intensive community crisis stabilization during the postcrisis period. Emerging crisis systems can leverage these emerging services and approaches to facilitate successful transitions for individuals in need.
Lessons of the Boom: A Playbook for Crisis Centers to Prevent, Survive, and Respond to Active Assailants, Targeted Violence, and Mass Violence
Rozel JS and Soliman L
Modern crisis centers need to be prepared for mass shootings, active assailant incidents, and related forms of targeted violence. While crisis engagement has traditionally been seen as a "right of boom" or post-incident responder, crisis leaders need to prepare their teams to identify people at risk for violence, use tools like Behavioral Threat Assessment and Management to reduce risk in those persons, and prepare their teams for potential incidents in their community. Evidence suggests that acute stressors are a common proximal risk factor for severe violence implying a potential synergy for using crisis services as a tool for prevention of violence.
Attending to Persons with Intellectual and/or Other Developmental Disorders in Crisis Settings
Anacker L, Edwards M, Nonnemacher S and Pinals DA
Crisis response is growing across the United States with increasingly broad phone, text, and chat response systems that lead to triaging callers who may be in need of further outreach. This might include deploying a mobile crisis response team and/or referring a caller to a crisis stabilization unit. The information set forth earlier aims to help advance the field and individual practices to ensure that persons with intellectual and/or other developmental disorders receive equivalent care and treatment with information that helps focus on this population's unique features and needs.
Policy, Design, and Critical Reflections on Behavioral Health Crisis Services for People Experiencing Homelessness
Jackson SW, Castillo EG, Myrick KJ and Goldman ML
People experiencing homelessness in crisis have unique structural vulnerabilities and social needs, most importantly lack of housing. Ideal crisis services for people experiencing homelessness must safeguard against criminalization and displacement during periods of crisis, prioritize equity, and provide housing interventions alongside mental health treatment at every stage in the crisis continuum. By outlining how to tailor crisis system financing and accountability, service component and capacity, and clinical best practices, the authors aim to provide hope and guidance for communities aiming to create an ideal crisis system for people experiencing homelessness.
Youth Crisis: The Current State and Future Directions
Foster AA, Zabel M and Schober M
The number of children and youth experiencing behavioral health crisis in the United States is substantially increasing. Currently, there are shortages to home-based and community-based services as well as psychiatric outpatient and inpatient pediatric care, leading to high emergency department utilization. This article introduces a proposed crisis continuum of care, highlights existing evidence, and provides opportunities for further research and advocacy.
Mental Health Crisis Responses and (In)Justice: Intrasystem and Intersystem Implications
Williams K, French A, Jackson N, McMickens CL, White D and Vinson SY
Mental health crises among people who are marginalized merit special consideration. These groups are both overserved and underserved by mental health crisis systems: over-represented in acute treatment settings by number while facing inequities in outcomes. The predisposing, precipitating, and perpetuating factors that contribute to crises, however, neither begin nor end with the mental health system. Rather, these factors are multisystemic. As an illustration of this concept, this article highlights select marginalized groups, those that have faced inequities in mental health diagnosis and treatment due to race, medical complexity, age, and criminal justice system involvement.
Behavioral Health Crisis Services: From Policy to Practice
Balfour ME and Goldman ML
Technology-based Cognitive Behavioral Therapy Interventions
Newby JM, Upton E, Mason E and Black M
Technology-delivered cognitive behavioral therapy (CBT) has enabled more people to access effective, affordable mental health care. This study provides an overview of the most common types of technology-delivered CBT, including Internet-delivered, smartphone app, and telehealth CBT, as well as their evidence for the treatment of a range of mental health conditions. We discuss gaps in the existing evidence and future directions in the field for the use of technology CBT interventions.
Improving Exposure Therapy: Rationale and Design of an International Consortium
Smits JAJ, Abramowitz JS, Arch JJ, Papini S, Anderson RA, Dixon LJ, Graham BM, Hofmann SG, Hoyer J, Huppert JD, Jacquart J, Johnson D, McEvoy PM, McKay D, Newby J, Otto MW, Pittig A, Rief W, Rosenfield D, Timpano KR, Wannemüller A and
The Exposure Therapy Consortium (ETC) was established to advance the science and practice of exposure therapy. To encourage participation from researchers and clinicians, this article describes the organizational structure and activities of the ETC. Initial research working group experiences and a proof-of-principle study underscore the potential of team science and larger-scale collaborative research in this area. Clinical working groups have begun to identify opportunities to enhance access to helpful resources for implementing exposure therapy effectively. This article discusses directions for expanding the consortium's activities and its impact on a global scale.
An Overview of Research on Acceptance and Commitment Therapy
Levin ME, Krafft J and Twohig MP
This review summarized recent systematic reviews and meta-analyses on randomized controlled trials evaluating acceptance and commitment therapy (ACT). Although the strength of evidence varies, overall there is plausible evidence for the efficacy of ACT for a wide range of areas including depression, anxiety disorders, obsessive-compulsive and related disorders, psychosis, substance use disorders, chronic pain, coping with chronic health conditions, obesity, stigma, and stress and burnout. ACT is also efficacious when delivered in digital self-help formats. Reviews of mediation research indicate ACT works through increasing psychological flexibility.
Advancements in Cognitive Behavioral Therapy
de Kleine RA, Smits JAJ and Hofmann SG