Brachytherapy

From patient to pioneer: The inspiring journey of Dr. Brian Moran
Agarwal M and Orio P
HDR brachytherapy combined with external beam radiotherapy for unfavorable localized prostate cancer: A single center experience from inception to standard of care
Yeung KD, Crook J, Arbour G, Araujo C, Batchelar D, Kim D, Petrik D, Rose T and Bachand F
High dose rate (HDR) brachytherapy is increasingly adopted for dose escalation in prostate cancer treatment. We report the clinical efficacy and toxicity of HDR prostate brachytherapy combined with external beam radiotherapy (EBRT) and evaluate the predictability of the biochemical definition of cure of 4-year PSA ≤0.2 ng/mL for failure free survival (FFS).
Learning curve and proficiency assessment for gynecological brachytherapy amongst radiation oncology trainees in India: Results from a prospective study
Kumar B, Mittal P, Gupta A, Mulani J, Bhajbhuje R, Kannan S, Jain J and Chopra S
The quality of cervical cancer intracavitary brachytherapy (ICBT) depends on the training and experience of the radiation oncologist (RO). The present study was performed to establish primary learning curve for ICBT.
Ultrasound and CT-guided implantation of iodine-125 seeds combined with transarterial chemoembolization for recurrent hepatocellular carcinoma at complex sites after hepatectomy
Wang Y and Feng J
The objective of this study was to evaluate the efficacy and safety of TACE combined with 125I seeds (TACE-125I) in the treatment of recurrent HCC at complex sites after hepatectomy.
Early outcomes following local salvage treatment with MRI-assisted low-dose rate brachytherapy (MARS) for MRI-visible postsurgical bed recurrences and focal intraprostatic recurrences
Hassanzadeh C, Mohamad O, Bruno T, Wang L, Kudchakar R, Bathala T, Sanders J, Mok H, McGuire S, Kuban D, Hoffman K, Nguyen Q, Park R, Thames H, Corn P, Chapin B, Choi S, Tang C and Frank S
To determine outcomes of MRI-assisted radiosurgery (MARS) for salvage brachytherapy using the radioisotope Pd after various upfront treatments including surgery, external beam radiotherapy, and brachytherapy.
Quality control study of cervical cancer interstitial brachytherapy treatment plans using statistical process control
Chen X, Shi X, Zhang H and Pang H
This study explored using statistical process control for quality control of cervical cancer interstitial brachytherapy treatment plans.
3D-printed radiopaque episcleral plaques with radioactive collimating cavities for enhanced dose delivery in brachytherapy
Zekraoui S, Lescot T, Akbari Taemeh M and Fortin MA
Episcleral plaque brachytherapy (EPBT) is a well-established treatment. However, the lateral dose to healthy tissues, such as the sclera, retina, and optic nerve is often problematic and results in side effects. This study proposes an innovative approach based on the 3D-printing of radiopaque polymer plaques featuring cylindrical radioactive cavities (CRC) with a potential collimating effect on radiation delivery to tumors.
The influence of time and implants in high-dose rate image-guided adaptive brachytherapy for locally advanced cervical cancer
Cagetti LV, Gonzague-Casabianca L, Ferré M, Gilhodes J, Lambaudie E, Blache G, Jauffret C, Provansal M, Sabatier R and Tallet A
To compare the clinical outcomes of two different schedules of modern image-guided adaptive brachytherapy (IGABT) in patients underwent chemoradiotherapy (CCRT) and high-dose rate (HDR) brachytherapy (BT) for locally advanced cervical cancer treated (LACC) METHODS AND MATERIALS: Data from medical records of all consecutive patients with histologically proven cervical cancer (FIGO 2018 stage IB-IVA) treated by HDR-BT after CCRT at our institution between 2016 and 2021 were reviewed.
A retrospective study on ruthenium-106 and strontium-90 eye-plaques treatment for retinoblastoma: 16-years clinical experience
Yarovoy AA, Volodin DP and Yarovaya VA
To retrospectively evaluate the efficacy of plaque brachytherapy for the treatment of retinoblastoma.
Towards U-Net-based intraoperative 2D dose prediction in high dose rate prostate brachytherapy
Knull E, Smith CW, Ward AD, Fenster A and Hoover DA
Poor needle placement in prostate high-dose-rate brachytherapy (HDR-BT) results in sub-optimal dosimetry and mentally predicting these effects during HDR-BT is difficult, creating a barrier to widespread availability of high-quality prostate HDR-BT.
High-dose-rate (2 fractions of 13.5 Gy) and low-dose-rate brachytherapy as monotherapy in prostate cancer. Long term outcomes and predictive value of nadir prostate-specific antigen
Rodríguez Villalba S, Guevara Barrera D, Suso-Martí L, Sanchis-Sánchez E, Pérez-Calatayud J, Lago Martín JD, Blázquez Molina F and Santos Ortega M
This study aims to evaluate the outcomes of patients treated for low-risk (LR) and favorable intermediate risk (FIR) prostate cancer with brachytherapy (BT) in monotherapy with LDR or HDR and its relationship with nadir PSA (nPSA).
Mature effectiveness and toxicity outcomes associated with three treatment schedules of high-dose-rate brachytherapy monotherapy for favorable-risk prostate cancer
Salari K, Ye H, Martinez AA, Sebastian E, Limbacher A, Marvin K, Thompson AB, Nandalur SR, Chen PY and Krauss DJ
To present long-term toxicity and effectiveness outcomes of three prostate high-dose-rate (HDR) brachytherapy schedules: 38 Gy in 4 fractions, 24 Gy in 2 fractions, and 27 Gy in 2 fractions for men with low- or intermediate-risk prostate cancer.
Impact of robust optimization on patient specific error thresholds for high dose rate prostate brachytherapy source tracking
Koprivec D, Belanger C, Beaulieu L, Chatigny PY, Rosenfeld A, Cutajar D, Petasecca M, Howie A, Bucci J and Poder J
The purpose of this study was to compare the effect of catheter shift errors and determine patient specific error thresholds (PSETs) for different high dose rate prostate brachytherapy (HDRPBT) plans generated by different forms of inverse optimization.
Postoperative high-dose-rate brachytherapy alone in stage T1-3N0M0 oral cancer with negative prognostic factors: A retrospective study
Tuček L, Sirák I, Pohanková D, Kašaová L, Grepl J, Paluska P, Hodek M, Vošmik M, Mustafa BA, Čermánková E and Petera J
To evaluate treatment outcomes and toxicity in patients with stage T1-3N0M0 oral cancer treated with surgery followed by high-dose-rate brachytherapy (HDR-BT).
Evaluation of dose distribution to the tumor and organs at risk for cervical cancer patients treated using HDR-ICBT without central tandem applicator: A single center based experience
Foya JA, Kumwenda MJ, Amour KO and Masana JJ
Cervical cancer is the most prevalent type of cancer among women in numerous low and middle-income countries. Tandem-based applicator is a widely used technique in High Dose Rate Intercavitary Brachytherapy (HDR-ICBT) for treating cervical cancer. For cases where central tandem insertion is not feasible due to patient-specific conditions, a ring-only applicator is used as an alternative. This paper presents an assessment of the impacts of dose distribution on cervical cancer treatment using HDR-ICBT without a central tandem applicator.
Transition from point A to volume based image guided brachytherapy across a network of centers in India through workshop and mentoring
Bajwa HK, Singamsetty M, Lal M, Sidhu MS, Aggarwal S, Agarwal R, Murali M, S DK, Natte R, Chaudhari S, Gupta V and Beriwal S
To demonstrate how workshop and mentoring across a network of radiotherapy centers helped in transitioning from point A to volume-based image guided brachytherapy in carcinoma cervix.
Development and implementation of a 3d-HDR brachytherapy program for cervical cancer in a sub-Saharan African centre
Joseph A, Balogun O, Adegboyega B, Salako O, Irabor OC, Ajose A, Adeneye S, Alabi A, Ohazurike E, Ogamba CF, Oladipo A, Fagbemide O, Habeebu M, Puthoff D, Onitilo A, Ngwa W and Nwachukwu C
Cervical cancer is the second most common cancer among women in Nigeria where, the gap between need for, and access to, radiation therapy including brachytherapy is significant. This report documents the implementation of the first three-dimensional high-dose-rate (3D-HDR) brachytherapy service for cervical cancer in Nigeria.
3D-printed template assisted intracavitary/interstitial brachytherapy for cervical cancer using repeat FMEA: Correspondence
Daungsupawong H and Wiwanitkit V
Escalating the dose of high-dose-rate brachytherapy combined with external beam radiotherapy improves the disease control rate in patients with high- or very-high-risk prostate cancer
Inagaki T, Noda Y, Iwahashi Y, Naka T, Kojima M, Inagaki R, Shimono R, Awaya A, Kohjimoto Y, Hara I and Sonomura T
High-dose-rate brachytherapy (HDR-BT) combined with external beam radiotherapy (EBRT) is an effective treatment for patients with high- and very-high-risk prostate cancer. We sought to identify the factors associated with reduced biochemical recurrence rates following HDR-BT.
"Erratum to keeping your best options open with AI-based treatment planning in prostate and cervix brachytherapy" [Brachytherapy Volume 23, ISSUE 2, P188-198, March 2024]
Dickhoff LRM, Scholman RJ, Barten DLJ, Kerkhof EM, Roorda JJ, Bouter A, Velema LA, Stalpers LJA, Pieters BR, Bosman PAN and Alderliesten T
Efficacy and safety of chemotherapy combined with iodine-125 seed brachytherapy for intermediate and advanced oncogenic driver gene-negative non-small cell lung cancer
Xia MH, Liu KC, Zhao W, Cheng YZ, Shi LP, Bi LQ, Guo XR, Zhang MX and Lv WF
To compare the effectiveness and safety of CT-guided iodine-125 seed brachytherapy in conjunction with chemotherapy against chemotherapy alone for the management of intermediate and advanced non-small cell lung cancer (NSCLC) lacking oncogenic driving genes.