Journal of Stroke & Cerebrovascular Diseases

Letter to the editor regarding "Electroacupuncture improves vascular cognitive impairment no dementia: A randomized clinical trial"
Wu Y and Liang Y
3DSlicer software-assisted neuroendoscopic surgery compared with traditional surgery on surgical effects, complications, and safety evaluation in patients with intracerebral hemorrhage: A systematic review and meta-analysis
Han J, Han Z, Zhang R, Sun P, Zhang Y and Yao Y
This study aims to comprehensively evaluate the complications, effectiveness, and safety of neuroendoscopic surgery (NS) assisted by 3DSlicer software, compared to traditional surgery in patients with intracerebral hemorrhage (IH).
Cerebral Air Embolism: Process Change with Unintended Consequences
Baumann JJ, Hill M, Swank A and Medel R
During a cerebrovascular procedure, diligent care is made to ensure no air is present in lines and connectors. Should air enter the cerebral vasculature, cerebral air emboli can cause worsening neurological outcome or death. This communication outlines how a process change of refrigerating mixed heparin for storage lead to the presence of unintentional air, or off-gassing of the fluid.
Sickness absence and disability pension in patients treated with mechanical thrombectomy
Roland M, Rudberg AS, Arnberg F, Alexanderson K and Sjöstrand C
Stroke patients with large vessel occlusions risk long-term or permanent sickness absence. We aimed to analyze the proportions and days of sickness absence and disability pension in thrombectomy-treated patients.
Thromboelastography may assess the effect of anticoagulation reversal in intracranial hemorrhage
Zepeski A, Faine BA, Ghannam M, Olalde HM, Wendt L, Naidech A, Mohr NM and Leira EC
Intracranial hemorrhage (ICH) is a complication of oral anticoagulation and is associated with significant morbidity and mortality. Clinical need exists for biomarkers to measure anticoagulation in patients with factor Xa inhibitor-associated ICH to assess the hemostatic effect of reversal agents. This study explored the utility of thromboelastography (TEG) to assess anticoagulation in emergency department (ED) patients who received activated prothrombin complex concentrate (aPCC) reversal for factor Xa-inhibitor-associated ICH.
Post-procedural Plasma D-dimer Level May Predict Futile Recanalization in Stroke Patients with Endovascular Treatment
Zhao M, Dai Z, Liu R, Liu X and Xu G
High D-dimer levels may increase the likelihood of unfavorable clinical outcomes in patients with acute ischemic stroke. However, the impacts of serum D-dimer levels on outcomes of reperfusion treatment in patients with acute ischemic stroke have not been evaluated. This study aims to assess a possible relationship between serum D-dimer and functional outcomes in stroke patients with endovascular treatment (EVT).
Visual outcomes of central retinal artery occlusion: Exploring treatment strategies beyond the conventional time window
Yang CC, Weng CC, Chou YB, Huang YM, Hwang DK, Chen SJ and Lin TC
Central retinal artery occlusion (CRAO) is a vision-devastating emergency. However, widely-acknowledged treatment consensus is lacking and prehospital delays commonly occur. Hence, we aimed to investigate the visual outcomes of conservative treatments (CT), local intra-arterial fibrinolysis (LIF) and hyperbaric oxygen (HBO) therapy for non-arteritic CRAO (NA-CRAO) patients beyond the conventional time window.
Predictors of outcome in patients with presumed reversible cerebral vasoconstriction syndrome (RCVS)
Madapoosi A, McGuire LS, Fuentes A, Sanchez-Forteza A, Tshibangu M, Theiss P, Mrad TA, Amin-Hanjani S and Alaraj A
Reversible cerebral vasoconstriction syndrome (RCVS) is thought to be benign by nature, but a proportion of patients still suffer from neurological deficits on follow-up.
Burden and risk factors of stroke in Vietnam from 1990 to 2021 - a systematic analysis from global burden disease 2021
Truyen TTTT, Vo NLY, Vo QP, Phan TC, Le PNB, Nguyen HT, Heckard E, Liu H, Nguyen TQ, Nguyen TH, Nguyen TN, Zuin M and Nguyen T
Stroke is a leading cause of death in Vietnam. However, a comprehensive analysis of stroke burden remains limited. This study aims to investigate the burden of stroke and various risk factors in Vietnam from 1990 to 2021.
Association between body roundness index and stroke results from the 1999-2018 NHANES
Gan J, Yang X, Wu J, Mo P, Deng Y, Liu Y, Wu Y, Liu P, Ji L, Jiang H, Han Y, Chen Z, Li W, Zhu Y and Wu M
Obesity, especially visceral obesity, is a controllable risk factor associated with the incidence of stroke. The body roundness index (BRI) bridges the gap between traditional anthropometric methods of assessing fat distribution to predict the percentage of body fat and visceral adipose tissue, which can be used to decipher its population-based characteristics and potential association with stroke.
Association of antihypertensive drug target genes with stroke subtypes: A Mendelian randomization study
Zheng H, Wang W, Qiu W and Feng Y
Epidemiological and genetic studies have elucidated the effect of antihypertensive medication (AHM) on stroke subtypes varying upon drug classes, but which drug target genes, how, and where mediated this association remains unknown. We aimed to investigate the impact of AHM on stroke subtypes.
Corrigendum to "Blockage of p38MAPK in astrocytes alleviates brain damage in a mouse model of embolic stroke through the CX43/AQP4 axis" [J Stroke Cerebrovasc Dis. 2024 Dec;33(12):108085/Article Number: YJSCD_JSCVD-D-24-00861]
Chen W, Wu Z, Yin M, Zhang Y, Qin Y, Liu X and Tu J
Potential of low apolipoprotein A-I as a surrogate marker of vulnerable carotid artery plaques
Tsuchigauchi S, Matsushige T, Hashimoto Y, Masahiro H, Takahashi H, Kobayashi S, Shishido T, Hara N, Kaneyoshi K, Uchida S, Maki R and Yamashita H
Recent studies suggested that the medical control of atherogenic lipoproteins is not sufficient for stroke prevention. A low apolipoprotein A-I (apoA-I) level may play a crucial role in the anti-atherogenic effects of high-density lipoprotein (HDL-C) and may also be associated with symptomatic vulnerable plaques in carotid artery stenosis. Therefore, the present study investigated the relationship between apoA-I levels and the status of carotid artery stenosis.
Investigating causal associations of gut microbiota and blood metabolites on stroke and its subtypes: A Mendelian randomization study
Zhang R, Han L, Pu L, Jiang G, Guan Q, Fan W and Liu H
The causal relationships between gut microbiota, blood metabolites, and stroke and its subtypes remain unclear. This study aims to uncover the causal associations using Mendelian randomization.
Comparison of the associations between life's essential 8 and life's simple 7 with stroke: NHANES 1999-2018
Yuan Y, Tian P, Li L and Qu Q
This study aims to explore the association between Life's Essential 8 (LE8) and stroke and all-cause mortality, and compare whether it has an advantage over Life's Simple 7 (LS7).
Comparative efficacy and safety of tissue plasminogen activators (tPA) in acute ischemic stroke: A systematic review and network meta-analysis of randomized controlled trials
Shahid S, Saeed H, Iqbal M, Batool A, Masood MB, Ahmad MH, Rehman AU, Aemaz Ur Rehman M and Sultan F
Intravenous alteplase (ALT) is the standard treatment for acute ischemic stroke (AIS). However, recent trials comparing other tissue plasminogen activators (tPAs) like tenecteplase (TNK) and reteplase with ALT have yielded conflicting results. This necessitated a network meta-analysis to compare the efficacy and safety of various tPAs in AIS patients.
Association between systemic inflammatory response index and cerebral small vessel disease
Zhuang T, Xu X, Huang P and Zhang Y
This study aimed to explore the relationship between the Systemic Inflammatory Response Index (SIRI) and Cerebral Small Vessel Disease (CSVD), focusing on its key imaging markers.
Letter to the editor, regarding "Iatrogenic cerebral amyloid angiopathy: Two case reports to explore clinical heterogeneity and pathological patterns" recently published by Vera-Cáceres and colleagues
Zupan M, Oblak JP and Frol S
Serum uric acid levels and intracerebral hemorrhage: A two-sample Mendelian randomization study
Lu B, Sun X, Zhong Q and Sun Z
Previous observational studies have generated controversy regarding the correlation between serum uric acid (UA) levels and intracerebral hemorrhage (ICH), with the causal relationship remaining uncertain. To assess the potential causal relationship between serum UA levels and ICH, two-sample Mendelian randomization analysis was applied.
Trajectory of depressive symptoms in a longitudinal stroke cohort
Sewell K, Tse T, Churilov L, Linden T, Crewther S, Ma H, Davis SM, Donnan GA and Carey LM
Knowledge of the trajectory of post-stroke depression is important to identify high-risk patients, develop precise management programs and enhance prognosis. We aimed to characterise the course of depressive symptoms within the first year post-stroke and to evaluate associations with time.
Relationship between heart rate variability traits and stroke: a Mendelian randomization study
Liu W, Xin Y, Sun M, Liu C, Yin X, Xu X and Xiao Y
Previous observational studies have suggested a potential association between heart rate variability (HRV) and cerebrovascular disease. However, a causal relationship between the two has not yet been established.