INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

Effect of postoperative complications on 5-year survival following laparoscopic surgery for resectable colorectal cancer: a retrospective study
Lee JE, Kim KE, Jeong WK, Baek SK and Bae SU
The purpose of this study was to investigate the effects of postoperative complications on long-term survival after laparoscopic surgery for resectable colorectal cancer.
Letter to the editor regarding "Local excision versus total mesorectal excision for rectal cancer patients with clinical complete or near complete response after neoadjuvant chemoradiotherapy"
Yüksel BC
Laparoscopic ileopexy for afferent loop syndrome after restorative proctocolectomy-a retrospective case series
Hyldgaard Andersen S, Harsløf S and Tøttrup A
To study the effect of laparoscopic ileopexy in patients with afferent-loop syndrome (ALS) after restorative proctocolectomy (RP).
Diverting ileostomy for treatment of ileoanal pouch dysfunction: a technical note
Weng S, Mangana O, Calabrese P and Celentano V
The ileal pouch-anal anastomosis (IPAA) is a restorative procedure performed after proctocolectomy to improve quality of life in patients with colorectal conditions like ulcerative colitis, familial adenomatous polyposis, and selected cases of Crohn's disease and Lynch syndrome. However, severe pouch dysfunction can occur, often necessitating further surgical intervention.
Use of transanal irrigation (TAI) in the treatment of persistent bowel disorders in patients with endometriosis: A retrospective study
Orlandi S, Bocus P, Geccherle A, Ruffo G and Ceccaroni M
Endometriosis has a strong impact on women's quality of life (QoL). Pain is the main symptom of the disease, but bowel dysfunctions such as fecal incontinence, constipation and voiding difficulties are also reported. Patients could suffer from a Low Anterior Resection Syndrome (LARS)-like syndrome. Transanal irrigation (TAI), known to alleviate LARS-related symptoms, has been suggested to aid bowel dysfunction in endometriosis patients, potentially facilitating pelvic floor rehabilitation.
Ambulatory management of acute uncomplicated diverticulitis (AmbUDiv study): a multicentre, propensity score matching study
Mohamedahmed AY, Hamid M, Issa M, Albendary M, Sultana E, Zaman S, Bhandari S, Sarma D, Ball W, Thomas P and Husain N
Recent studies have suggested that ambulatory management is feasible for acute uncomplicated diverticulitis (AUD); however, there is still no consensus regarding the most appropriate management settings. This study presents a multi-centre experience of managing patients presenting with AUD, specifically focusing on clinical outcomes and comparing ambulatory treatment with in-patient management.
Biomarkers of systemic treatment response: MR images of intratumoral fat deposition in colorectal liver metastases (CRLM) after chemotherapy
Morawska I, Pasicz K and Cieszanowski A
Colorectal cancer cells containing mobile lipids are said to be an early indicator of chemotherapy effects. The objective of the study was to examine the frequency and clinical relevance of intratumoral fat deposition in colorectal liver metastases (CRLM) post-chemotherapy using dual-echo chemical shift gradient-echo magnetic resonance imaging (MRI).
Prognostic Value of Baseline Skeletal Muscle Index in Colorectal Cancer Patients Treated with Fruquintinib: A multi-center real world analysis
Tang W, Li F, Zheng H, Zhao J, Wei H, Xiong X, Chen H, Zhang C, Xie W, Zhang P, Gong G, Ying M, Guo Q, Wang Q and Fu J
The Skeletal Muscle Index (SMI) serves as an objective metric for assessing nutritional status in patients with malignant tumors. Research has found baseline nutritional status can influence both the efficacy and prognosis of targeted anti-tumor therapies, with growth factor tyrosine kinase inhibitors frequently inducing drug-related sarcopenia. Fruquintinib has received approval for the treatment of metastatic colorectal cancer. This study examines the prognostic significance of baseline SMI in patients with metastatic colorectal cancer undergoing treatment with fruquintinib. Additionally, the study investigates the incidence of SMI reduction following fruquintinib therapy to assess its impact on patient prognosis.
Patient-reported performance status and postoperative complications in elective colorectal cancer surgery
Pardes HY, Dohrn N, Dolin TG, Gögenur I and Klein MF
The purpose of this study was to evaluate the concordance between patient-reported performance status (prPS) and surgeon-reported performance status (srPS), and to assess the correlation between srPS and prPS and postoperative complications following elective colorectal cancer surgery. Not all patients are deemed suitable for undergoing a surgical procedure. We aimed to assess whether prPS can aid the surgeons' decision-making prior to surgery.
Long-term treatment outcomes of complicated acute diverticulitis in immunocompromised patients
Sancho-Muriel J, Cholewa H, Millán M, Quevedo D, Alvarez E, Nieto-Sanchez M, Blasco R, Giner F, Gomez MJ, Primo-Romaguera V, Frasson M and Flor-Lorente B
The main aim of this study was to determine the short- and long-term outcomes of the non-operative management of acute left-sided complicated diverticulitis (ALCD) in severely immunocompromised patients (IMS group) and compare them with immunocompetent patients (IC group). The secondary aim was to assess the necessity of an elective surgery following a successful prior non-operative management in the IMS group after a non-operative management of the first episode of ALCD.
Clinical outcome and long‑term prognosis after endoscopic submucosal dissection for colorectal tumors in patients aged 75 years or older: a retrospective observational study
Asayama N, Nagata S, Shigita K, Mouri Y, Ooie S, Matsumoto K, Aoyama T, Fukumoto A and Kaneko M
To determine the clinical outcomes of endoscopic submucosal dissection (ESD) for colorectal tumors in older patients and predictors of mortality.
Risk factors for postoperative complications in patients undergoing cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy: A meta-analysis and systematic review
Chen D, Ma Y, Li J, Wen L, Zhang G, Huang C and Yao X
Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) is one of the most effective treatments for intraperitoneal malignancies. However, current research on risk factors for postoperative complications needs to be more consistent. This study aimed to conduct a meta-analysis of the risk factors for postoperative complications in CRS + HIPEC patients.
Treatment indicators and prognostic factors in colorectal neuroendocrine neoplasms and adenocarcinoma with neuroendocrine differentiation: a single center retrospective study
Fu X, Wang C, Yu Y and Chen HN
This study compared survival and metastasis occurrence between colorectal neuroendocrine neoplasms (cNEN) and colorectal adenocarcinoma with neuroendocrine differentiation (cNED) and further explored their prognostic factors and treatment indicators.
Effect of kegel pelvic floor muscle exercise on improving urinary disorder in rectum cancer patients after rectal surgery: a randomized clinical trial
Shah-Abadi ME, Pak H, Kazemeini A, Najari D, Tafti SMA, Keramati MR, Keshvari A, Fazeli MS and Behboudi B
Postoperative urinary dysfunction poses a significant challenge for rectal cancer patients. While pelvic floor muscle training (PFMT) has shown promise in other contexts, its efficacy following rectal cancer surgery remains uncertain.
Inflammatory bowel disease, colitis, and cancer: unmasking the chronic inflammation link
Shahgoli VK, Noorolyai S, Ahmadpour Youshanlui M, Saeidi H, Nasiri H, Mansoori B, Holmskov U and Baradaran B
Chronic inflammation is a significant driver in the development of various diseases, including cancer. Colitis-associated colorectal cancer (CA-CRC) refers to the increased risk of colorectal cancer in individuals with chronic inflammatory bowel diseases (IBD) such as ulcerative colitis and Crohn's disease.
Impact on survival benefits of asymptomatic primary tumor resection after bevacizumab plus FOLFIRI as first-line therapy for patients with metastatic colorectal cancer with synchronous unresectable metastasis
Chen YC, Chang TK, Su WC, Yeh YS, Chen PJ, Huang PJ, Yang PH, Tsai HL, Wang JY and Huang CW
Metastatic colorectal cancer (mCRC) poses a clinical challenge and requires a combination of systemic therapy and conversion surgery. Although first-line chemotherapy and targeted therapy are considered the standard treatments for mCRC, the role of primary tumor resection (PTR) in asymptomatic synchronous mCRC with unresectable metastatic lesion after initial therapy remains relatively underexplored.
Correction to: A novel scoring system for predicting disease severity without CT imaging in acute diverticulitis
Mäntymäki LM, Grönroos J, Karvonen J and Ukkonen M
Inferior mesenteric artery preservation techniques in the treatment of diverticular disease: a systematic review of the literature
Agnesi S, Virgilio F, Frontali A, Zoni G, Giugliano M, Missaglia C, Balla A, Sileri P and Vignali A
The aim of this study is to analyze the impact of different surgical techniques used to preserve the inferior mesenteric artery on patient outcomes following left colonic resection.
PKG1 promotes the HIV-induced proliferation, migration, and fibrosis of vascular smooth muscle cells of hemorrhoids
Li Z, Chen Z, Liu C, Peng S and Wang N
Hemorrhoids are very common in patients with human immunodeficiency virus (HIV) infection. The risk of postoperative infection is significantly greater in HIV-positive patients than in HIV-negative individuals, and the wound healing time is significantly prolonged. This study aimed to investigate the role of HIV-associated hemorrhoids from the perspective of vascular smooth muscle cell (VSMC) function.
Commentary: treatment indicators and prognostic factors in colorectal neuroendocrine neoplasms and adenocarcinoma with neuroendocrine differentiation
Viswanathan D and Govindasamy R
RE: Comment on: "Implementing a no-drain policy for extraperitoneal colorectal anastomosis in a real-life setting: analysis of outcomes and surgeons' adherence"
Crippa J, Carvello M and Spinelli A