Various polymeric nanoparticles have been used as drug carriers in drug delivery systems (DDSs). Most of them were constructed from dynamic self-assembly systems formed via hydrophobic interactions and from structures that are unstable in an in vivo environment owing to their relatively weak formation forces. As a solution to this issue, physically stabilized core-crosslinked particles (CP) with chemically crosslinked cores have received attention as alternatives to the dynamic nanoparticles. This focused review summarizes recent advances in the construction, structural characterization, and in vivo behavior of polymeric CPs. First, we introduce a nanoemulsion-mediated method to create polyethylene glycol (PEG)-bearing CPs and their structural characterization. The relationship between the PEG chain conformations in the particle shell and the in vivo fate of the CPs is also discussed. After that, the development and advantages of zwitterionic amino acid-based polymer (ZAP)-bearing CPs are presented to address the poor penetration and the internalization of PEG-based CPs into tumor tissues and cells, respectively. Finally, we conclude and discuss prospects for application of polymeric CPs in the DDS field.

Two specific concepts have emerged in the field of materials science over the last several decades: nanosheets and supramolecular polymers. More recently, supramolecular nanosheets, in which these two concepts are integrated, have attracted particular attention, and they exhibit many fascinating characteristics. This review focuses on the design and applications of supramolecular nanosheets consisting of tubulin proteins and phospholipid membranes.

Light is a form of energy that can be converted to electric and chemical energies. Thus, organic photovoltaics (OPVs), perovskite solar cells (PSCs), photocatalysts, and photodetectors have evolved as scientific and commercial enterprises. However, the complex photochemical reactions and multicomponent materials involved in these systems have hampered rapid progress in their fundamental understanding and material design. This review showcases the evaluation-oriented exploration of photo energy conversion materials by using electrodeless time-resolved microwave conductivity (TRMC) and materials informatics (MI). TRMC with its unique options (excitation sources, environmental control, frequency modulation, etc.) provides not only accelerated experimental screening of OPV and PSC materials but also a versatile route toward shedding light on their charge carrier dynamics. Furthermore, MI powered by machine learning is shown to allow extremely high-throughput exploration in the large molecular space, which is compatible with experimental screening and combinatorial synthesis.

Liquid-crystalline (LC) water-treatment membranes obtained by in situ photopolymerization of ionic mesogenic monomers have been shown to efficiently remove viruses. In our previous works, bicontinuous cubic (Cub) and smectic (Sm) LC membranes prepared from ionic taper- and rod-shaped polymerizable mesogens, respectively, were used for this purpose. Here, we report the results of virus removal by columnar (Col) LC water-treatment membranes having ionic nanochannels obtained from ionic taper-shaped mesogens. These effects are compared with those obtained for Cub membranes. The effects of these Col and Cub LC ionic membranes on the removal of several viruses from their cocktail solution are also examined.

Inspired by ocean organisms, scientists have been developing adhesives for application in the marine environment. However, water and high salinity, which not only weaken the interfacial bonding by the hydration layer but also induce the deterioration of adhesives by erosion, swelling, hydrolysis, or plasticization, are detrimental to adhesion, resulting in specific challenges in the development of under-seawater adhesives. In this focus review, current adhesives that are capable of macroscopic adhesion in seawater were summarized. The design strategies and performance of these adhesives were reviewed based on their bonding methods. Finally, some future research directions and perspectives for under-seawater adhesives were discussed.