Critical analysis of hot topics in diabetic nephropathy related experimental research: A bibliometric analysis from 2018 to 2024
Diabetic nephropathy (DN) is a severe complication of diabetes mellitus and a leading cause of end-stage renal disease worldwide. Understanding trends in experimental research on DN is crucial for advancing knowledge and clinical management.
Corrigendum to "Factors associated with adherence to prevention guidelines of pressure injuries among Jordanian nurses in critical care units", [Journal of Tissue Viability, 34(1), February 2025, 100853]
Factors associated with adherence to prevention guidelines of pressure injuries among Jordanian nurses in critical care units
Pressure injury (PI) is a significant health issue and one of the greatest challenges in critical care units. Guidelines adherence to prevent PIs is not always optimal by critical care nurses. To our knowledge, there is no data about adherence to PI preventive guidelines among Jordanian critical care nurses, and this study aimed to fill this gap.
Application of infrared thermography for predicting pressure injury healing: A prospective study
An accurate assessment of pressure injury healing is crucial for the timely implementation of nursing intervention. This study aimed to investigate the accuracy of infrared thermography-based wound temperature measurement in predicting wound outcomes.
The role of biomaterials-based scaffolds in advancing skin tissue construct
Despite extensive clinical studies and therapeutic interventions, addressing significant skin wounds remains challenging, necessitating novel approaches for effective regeneration therapy. In the current review, we analyzed and evaluated the application, advancements, and future directions of biomaterials-based scaffolds for skin tissue construct. In addition, we investigated the role of other biological substitutes in promoting wound healing and skin tissue regeneration. The review highlights the impact of biomaterial-based scaffolds on skin tissue regeneration and wound healing. After presenting the physiological process of skin tissue regeneration, the review emphasizes the different biochemical components significant for skin healing and regeneration. Subsequently, it delves into the role of scaffolds in skin tissue engineering. Recent advancements in nanotechnology are also highlighted with a specific focus on the utilization of nanomaterials for enhancing healing, facilitating tissue regeneration, and promoting skin reconstruction. Biomaterial scaffolds have emerged as a potential intervention for wound healing forming the foundation of skin tissue regeneration. These scaffolds, intricate three-dimensional frameworks, serve as carriers for cells, medications, and genes, facilitating their delivery into the body. The integration of degradable porous scaffolds with biological cells offers a promising avenue for tissue repair. Biomaterials play a crucial role in tissue engineering, providing temporary mechanical support and facilitating cellular processes to augment skin tissue regeneration.
Diabetic foot ulcer related pain and its impact on health-related quality of life
Diabetic foot ulcers (DFUs) are a prevalent complication of diabetes. Individuals with DFUs can experience wound-related pain, which could be nociceptive and/or neuropathic in origin, which adversely affects health-related quality of life (HRQoL).
Knowledge levels and attitudes of Turkish nursing students regarding medical device-related pressure injuries and factors influencing them: A cross-sectional study
The aim of this study was to determine nursing students' levels of knowledge and attitudes regarding medical device-related pressure injuries (MDRPIs), as well as the factors influencing these.
The 'HAPI' project five years on: Incidence and prevalence of Hospital-Acquired Pressure Injuries in one local health district in Australia
From 2015 to 2018, the 'Hospital-Acquired Pressure Injury (HAPI)' project was implemented in one local health district in Australia and utilised an implementation science approach to address rising pressure injury (PI) incidence and prevalence rates. This paper aims to examine whether the project was successful in sustaining low PI incidence and prevalence rates over the five-years following implementation (spanning the 2018/2019 to 2022/2023 financial years and the 2019-2023 calendar years).
Adults living with dementia and chronic wounds, wound types, care challenges, and impact across dementia stages: A scoping review protocol
The objective of this scoping review is to map the existing evidence on the epidemiology, care challenges, and impacts of various wound types among individuals living with dementia across different stages of the disease.
A novel skin-like patch based on 3D hydrogel nanocomposite of Polydopamine/TiO nanoparticles and Ag quantum dots accelerates diabetic wound healing compared to stem cell therapy
Despite the advances in the development of therapeutic wearable wound-healing patches, lack self-healing properties and strong adhesion to diabetic skin, hindering their effectiveness. We propose a unique, wearable patch made from a 3D organo-hydrogel nanocomposite containing polydopamine, titanium dioxide nanoparticles, and silver quantum dots (PDA-TiO@Ag). The designed patch exhibits ultra-stretchable, exceptional-self-healing, self-adhesive, ensuring conformal contact with the skin even during movement. Our patch demonstrated potent antibacterial activity and significantly accelerated wound healing with a high wound closure rate of 99.2 % after 7 days. Remarkably, it enhanced diabetic skin wound healing compared to that achieved by adipose-derived stem cell (ADSC) therapy in a study involving 30 adult male albino rats. Microscopic analysis highlights the promising hierarchical architecture structure of the patch for wound healing applications, suggesting its potential to create a favorable environment for healing and provide long-lasting benefits. Histopathological analysis and immunohistochemical staining revealed faster healing and enhanced cellular response in the patch-treated group compared to both stem cell and control groups. Notably, the patch promoted complete re-epithelization and a significant increase in vascular endothelial growth factor (VEGF) expression on day 7, indicating improved angiogenesis. This self-healing, multifunctional patch offers a promising alternative to stem cell therapy for accelerating diabetic wound healing, showcasing its potential for clinical translation. The combination of durability, biocompatibility, and antibacterial properties makes the patch a promising candidate for advanced wound management and offering faster, more complete restoration than other approaches.
Vibration therapy for patients with hard-to-heal wounds: A systematic review and meta-analysis of experimental studies
Hard-to-heal wounds lead to functional loss, decreased quality of life, and prolonged hospitalization due to delayed healing. The healthcare costs of managing such wounds are substantial. Vibration therapy has been proposed as an alternative treatment for hard-to-heal wounds but no comprehensive reviews have quantitatively analyzed its efficacy.
Effect of aromatherapy on pruritus in people receiving hemodialysis treatment: Systematic review
Lack of a complete understanding of the pathophysiology of pruritus directs patients to different treatments. There is little data on the effect of aromatherapy on itching in patients receiving hemodialysis treatment. However, the effect of aromatherapy on pruritus in patients receiving hemodialysis treatment remains unclear.
The effect of case-supported concept map education on nursing students' knowledge of and attitudes toward pressure injury prevention
This study aimed to evaluate the impact of case-based concept map education on nursing students' knowledge of and attitudes toward pressure injury prevention.
Differences on lower trapezius pressure pain threshold, muscle strength and muscle thickness in individuals with chronic neck pain and active or latent myofascial triggers points
Myofascial trigger points (MTrPs) in the lower trapezius have been recognized as an important source of neck pain. This study aims to compare the lower trapezius muscle strength, pressure pain threshold (PPT) and muscle thickness at rest and contraction between participants and painful vs. no-painful side with active and latent MTrPs; and to examine the associations among these variables with pain intensity, duration and disability in patients with neck pain.
Knowledge, attitude, and practice of clinical nurses towards medical device-related pressure injury prevention: A systematic review
To evaluate clinical nurses' knowledge, attitude, and practice toward MDRPI prevention.
Prevalence, risk level and risk factors of diabetic foot ulcer among adult individuals with diabetes in the Southeastern Anatolia Region of Turkiye
The aim of the study was to determine the prevalence, risk, and predisposing factors of diabetic foot ulcers in adults with diabetes.
Medical device-related pressure injuries: The mediating role of attitude in the relationship between ICU nurses' knowledge levels and self-efficacy
This study examines the mediating role of attitude towards preventing pressure injuries (PIs) in the effect of knowledge about Medical Device-Related Pressure Injuries (MDRPI) on self-efficacy in PI management among Turkish intensive care unit (ICU) nurses.
Comparing the efficacy of two different types of dressings on patients with pressure injuries in long-term care facilities
"I was surprised that the veins were the cause" - The illness trajectory of people with venous leg ulcers: A qualitative study
Patients with venous leg ulcers (VLUs) often carry out inadequate self-care. Person-centered care is recommended as effective support. Understanding the illness trajectory from the patient's perspective could be a way to better understand patients' needs.
Turkish nurses' knowledge, attitudes and practices in the management of incontinence associated dermatitis: A descriptive and cross-sectional study
This study aimed to determine nurses' current knowledge, attitudes, and practices in adult intensive care units and palliative care clinics regarding incontinence-associated dermatitis (IAD).
Evaluation of storage parameters of platelet-rich plasma in functional assay of epithelial gap repair
Platelet-rich plasma (PRP), produced from autologous blood and containing growth factors, has shown promise in treating various conditions, including diabetic wounds. However, as expected, patient compliance is low in the context of repeated treatments as required for hard-to-heal wounds. This study investigates the efficacy of PRP stored under refrigeration for up to 2 weeks in promoting in-vitro human epithelial cell gap closure. PRP was prepared from six healthy individuals and immediately split into sterile test tubes for storage at 4 °C; the impact of fresh PRP on epithelial gap closure was compared to paired PRP samples stored for one and two weeks. According to gap closure analysis, 5 out of 6 individuals depicted accelerated epithelial gap closure compared to control conditions. There was no significant difference between fresh and refrigerated samples. An overall benefit was observed for using 1-week old samples over 2-week-old samples. Interestingly, according to a 6-hr epithelial gap analysis, significantly accelerated cell migration was obtained by 1-week-old refrigerated samples compared to their corresponding fresh PRP samples. The current study provides data in support of increasing the accessibility of PRP treatment for patients with hard-to-heal wounds. Patients can potentially self-treat between wound clinic appointments by using refrigerated sterile aliquots of their fresh PRP. Notably, by the end of two weeks, refrigerated PRP will not act as fresh PRP. More research is needed to fully investigate the effect of refrigeration on PRP sample efficacy, including larger cohorts, clinical wounds, and an evaluation of the molecular fingerprint of refrigerated PRP samples.