Drawing on residential history data from two household surveys conducted in Guangzhou in 2005 and 2010, this paper compares the pattern of intra-city residential moves of local residents and that of migrants. The findings show different trajectories of residential moves for the two groups. While migrants showed increasing mobility over time, residential moves of locals first rose until the early 2000s, then declined steadily afterward. Moreover, the determinants of residential moves of migrants differ from those of the local population. Also, whereas residential moves for the local population are subject to changing factors over time, drivers of relocation for migrants remain more or less stable.