Journal of Clinical Sleep Medicine

Asian adult sleep medicine fellowship training curriculum: one curriculum, many contexts
BaHammam AS, Al-Abri MA, Al Oweidat K, Amra B, Chan JWY, Chirakalwasan N, Dhafar H, Dizon RV, Gupta R, Duong-Quy S, Han F, Hong SB, Ismail AI, Jahrami H, Jamil MG, Jung KY, Kadotani H, Leow LC, Lee PL, Munshi F, Tedjasukmana R, Wing YK, Inoue Y and
To develop a comprehensive Asian adult sleep medicine fellowship training curriculum to address the significant disparities in sleep medicine training across Asia, guided by the principle of "One Curriculum, Many Contexts," providing a standardized yet adaptable framework for sleep medicine education across the diverse healthcare landscapes of Asian countries.
Positional therapy: is it ready for prime time?
Manchanda S and Sigua NL
CBT-I access and engagement considerations: if we build it, will they access?
Martin AM and McCrae CS
A sleep promotion program for insufficient sleep among adolescents: a pilot feasibility randomized controlled trial
Levenson JC, Goldstein TR, Wallace ML, Witt R, Harvey A, Buysse D, Rofey D, Suffoletto B and Miller E
To examine the feasibility, acceptability, and impact of a Sleep Promotion Program (SPP).
The impact of screen time and parental habits on children's sleep quality
Ferrari D, Morelhão PK, Moreira GA, Tufik S and Andersen ML
A strategic approach of the management of sleep-disordered breathing in multiple system atrophy
Laga A, Bauters F, Hertegonne K, Tomassen P, Santens P and Kastoer C
Multiple system atrophy (MSA) is a rare neurodegenerative disorder characterized by autonomic dysfunction associated with a combination of cerebellar, parkinsonian, or pyramidal signs. Sleep-disordered breathing (SDB) such as stridor, obstructive sleep apnea (OSA) and central sleep apnea (CSA) are common in MSA and can impact survival. Several studies have evaluated treatment modalities. However, the optimal strategy often remains unclear in these patients. This review aims to provide an overview of the current evidence on treatment of SDB in MSA.
Using expanded diagnostic criteria mitigates gender disparities in diagnosis of sleep-disordered breathing
Haile K, Mungarwadi M, Ibrahim NA, Vaishnav A, Carrol S, Pandya N, Yarandi H, Sankari A, Martin JL and Badr MS
Mitigating gender inequality in the diagnosis and management of sleep-disordered breathing (SDB) is of paramount importance. Historically, the diagnostic criteria for SDB were based on male physiology and did not account for variations in disease manifestation based on sex. Some payors use a definition of hypopnea that requires a 4% oxygen desaturation (AHI-4) to determine coverage for treatment, while the criteria recommended by the American Academy of Sleep Medicine requires either a 3% oxygen desaturation or an arousal (AHI-3A). This study examined the diagnostic implications of these two definitions for men and women in a clinical setting.
Adults with Down syndrome and obstructive sleep apnea treated with hypoglossal nerve stimulation
Huyett P, Santoro SL, Oreskovic NM and Skotko BG
To examine the feasibility, adherence to therapy, and efficacy of hypoglossal nerve stimulation (HGNS) in adults with Down syndrome (DS) with obstructive sleep apnea.
Improvement of CPAP tolerance and adherence in a patient with obstructive sleep apnea with the use of nasal steroids and nasal oxymetazoline
Anokwute A, Manchanda S and Wallach PM
Adherence to positive airway pressure (PAP) therapy is a challenge in patients with allergic rhinitis. We present a case of a 62-year-old male with OSA who had been struggling with PAP therapy for ten years. Intranasal fluticasone alone did not result in tolerance of PAP therapy. However, the combination of once- daily intranasal oxymetazoline with fluticasone led to significant improvement in tolerance and adherence to PAP therapy. While twice daily oxymetazoline alone has been associated with developing rhinitis medicamentosa, this side effect was not experienced by our patient. Some studies have shown that using intranasal oxymetazoline along with an intranasal steroid once daily for four weeks demonstrated improved effectiveness in relieving nasal symptoms with no development of rebound congestion or rhinitis medicamentosa. This strategy may be helpful in improving CPAP tolerance for patients with concurrent OSA and rhinitis, a potential area to explore in the future to improve PAP adherence.
Pulmonary arterial hypertension therapies in patients with obesity hypoventilation syndrome: a case series
Daigo K, Hiraide T, Momoi M, Shinya Y, Katsumata Y, Kishino Y, Shiraishi Y, Nishiyama T, Kohsaka S and Ieda M
Obesity hypoventilation syndrome (OHS) is caused by complex interactions between multiple pathological processes, including diminished respiratory drive and sleep-related breathing alterations, leading to structural and functional respiratory impairment and ultimately, pulmonary hypertension (PH). Because PH is closely associated with OHS, thoroughly evaluating its etiology is essential, and individualized treatments must be considered. We describe two patients with OHS exhibiting severe PH with pulmonary vascular resistance exceeding 5 Wood units; both were classified as Group 1 PH, i.e., pulmonary arterial hypertension (PAH). Initially admitted to our hospital complaining of dyspnea, both patients commenced PAH therapies in addition to positive airway pressure therapy and diuretics, improving their hemodynamic status, dyspnea, and exercise capacity, and finally enabling their discharge. These findings suggest that PAH can coexist with OHS, and PAH therapies, introduced with careful consideration, may provide substantial benefits for select patients.
Genetic QT score as a predictor of sudden cardiac death in participants with sleep-disordered breathing in the UK Biobank
Arora A, Zareba W, Woosley RL, Klimentidis YC, Patel IY, Quan SF, Wendel C, Shamoun F, Guerra S, Parthasarathy S and Patel SI
The goal of this study was to evaluate the association between a polygenic risk score (PRS) for QT prolongation (QTc-PRS), QTc intervals and sudden cardiac death (SCD) in participants enrolled in the UK Biobank with and without sleep-disordered breathing (SDB).
Consumer sleep technology use in individuals with obstructive sleep apnea: does it have a role in monitoring treatment response?
Lenze NR, Kazemi RJ, Ikeda AK, Vijayakumar P, Goldstein CA, Stanley JJ, Brenner MJ and Hoff PT
Consumer sleep technology (CST) has an emerging role in monitoring sleep, including screening or surveillance of sleep disorders; however, few data are available on CST in patients with obstructive sleep apnea (OSA). We analyzed attitudes towards CST and patterns of CST use among individuals with OSA. Among 251 respondents (mean age 57.5 years; 58.2% female), 66.5% reported CST use, and 92.0% indicated that monitoring OSA treatment response would be a useful feature of CST. Individuals with a household income < $30,000 (OR 0.26; p=0.008) or identifying as a minority/other race (OR 0.15; p=0.021) were less likely to use CST. Older age (beta-coefficient 0.05; p<0.001), Medicare insurance (beta-coefficient 1.26; p=0.006), and positive airway pressure use (beta-coefficient; p=0.008) were associated with increased nights/week of CST use. These findings demonstrate a high perceived value of CST for monitoring treatment response among individuals with OSA, but disparate use by sociodemographic and clinical factors.
The complexity of employing "optimal AHI/RDI cutoffs" in assessing the performance of OSA-detecting wearables
Chiang AA, Holfinger S and Schutte-Rodin S
Perspective: Improving the understanding of sleep deprivation and strategies for fatigue management across the medical education continuum: a call to action
Alter IL, Kutler RB, Cai Y and Rosen IM
The kindling of the flame
Badr MS
Sleep-disordered breathing in a multi-ethnic cohort of preterm adolescents and adults: assessment of neonatal and subsequent risk factors
Sanchez-Solano NJ, Barton GP, Martinez-Fernandez T, Lee M and Goss KN
Determine whether preterm-born adolescents and adults have sleep-disordered breathing (SDB), as documented by abnormal overnight oximetry.
Validation of automated detection of REM sleep without atonia using in-laboratory and in-home recordings
Levendowski DJ, Chahine LM, Lewis SJG, Finstuen TJ, Galbiati A, Berka C, Mosovsky S, Parikh H, Anderson J, Walsh CM, Lee-Iannotti JK, Neylan TC, Strambi LF, Boeve BF and St Louis EK
To evaluate the concordance between visual scoring and automated detection of REM sleep without atonia (RSWA) and the validity and reliability of in-home automated-RSWA detection in REM sleep behavior disorder (RBD) patients and a control group (CG).
A novel method for positive airway pressure delivery: pulsating airflow
Oren L, Gutmark E and Romaker A
The primary objective is to determine if pulsating airflow can achieve therapeutic pharyngeal pressure levels without requiring a tight-sealing mask.
Non-contact respiratory monitoring during sleep: comparison of the touchless flow signal with RIP signal to assess respiratory events
Addison PS, Brewer L, Sundar KM, Farney R, Smit P, Antunes A and Montgomery D
A non-intrusive sleep monitoring technology based on the data from a commercially available depth sensing camera has been utilized for respiratory monitoring and shown to have good performance in assessing respiratory rates across a range of rates. This non-contact, or , technology allows continuous respiratory monitoring without attaching probes to the patient. We have noticed a strikingly similar morphology between the touchless flow signal (NCM) and the flow signal derived using the chest and abdomen respiratory inductance plethysmography (RIP) bands. Here we report on a quantitative assessment of the morphological similarity between the two signals for a cohort of patients undergoing polysomnography (PSG).
The five faces of flow in asynchronous hypoglossal nerve stimulation
Harkins TR, Soh LJM, Seay EG, Thuler E, Schwartz AR and Dedhia RC
Central sleep apnea: realignment required
Randerath W and Schwarz EI