Practice patterns for acquiring neuroimaging after pediatric in-hospital cardiac arrest
To determine which patient and cardiac arrest factors were associated with obtaining neuroimaging after in-hospital cardiac arrest, and among those patients who had neuroimaging, factors associated with which neuroimaging modality was obtained.
Targeted Mild Hypercapnia and Acute Kidney Failure after Cardiac Arrest: Lessons from the TAME Trial
Development of a health equity tool in resuscitation sciences and application to current research in extracorporeal cardiopulmonary resuscitation for cardiac arrest
Extracorporeal cardiopulmonary resuscitation (ECPR) is increasingly used for adults with cardiac arrest (CA) refractory to Advanced Cardiovascular Life Support (ACLS). Concerns exist that adding ECPR could worsen health inequities, defined as differences in health outcomes that are unfair or unjust. Current guidelines do not explicitly address this issue. This study narratively reviews the latest evidence on ECPR, focusing on its implications for health equity and derives a health equity tool that may serve as a basis of comparison for resuscitation sciences.
Can we reliably predict neurological recovery after cardiac arrest in children?
Towards a common terminology of ventilation during cardiopulmonary resuscitation
Manual and mechanical ventilation during cardiopulmonary resuscitation are critical yet poorly understood components of resuscitation care. In recent years, intra-arrest ventilation has been the subject of a growing number of laboratory and clinical investigations. Essential components to accurately interpret or reproduce original investigations are the exact measurement and transparent reporting of key ventilation parameters, such as volumes and airway pressures obtained during ongoing cardiopulmonary resuscitation. Chest compressions lead to frequent intrathoracic and intrapulmonary pressure rises which interact with artificial ventilation. The resulting unique phenomena during continuous chest compressions with asynchronous ventilation and an advanced airway, necessitate a nuanced conceptualization supported by a common terminology. Based on previous original investigations and observations, we describe intra-arrest ventilation parameters and propose a common terminology integrating established and novel concepts. The proposed terminology may serve as a methodological and reporting consideration for future research of intra-arrest ventilation. Additionally, it may serve as a foundation for an authoritative scientific consensus process, which may further facilitate the transparent reporting and reproducible science needed to understand cardiopulmonary resuscitation and improve survival for cardiac arrest patients.
A retrospective 'target trial emulation' comparing amiodarone and lidocaine for adult out-of-hospital cardiac arrest resuscitation
The administration of amiodarone or lidocaine is recommended during the resuscitation of out-of-hospital cardiac arrest (OHCA) patients presenting with defibrillation-refractory or recurrent ventricular fibrillation or ventricular tachycardia. Our objective was to use 'target trial emulation' methodology to compare the outcomes of patients who received amiodarone or lidocaine during resuscitation.
The association between initial defibrillation dose and outcomes following adult out-of-hospital cardiac arrest resuscitation: a retrospective, multi-agency study
Effective defibrillation is essential to out-of-hospital cardiac arrest (OHCA) survival. International guidelines recommend initial defibrillation energies between 120 and 360 Joules, which has led to widespread practice variation. Leveraging this natural experiment, we aimed to explore the association between initial defibrillation dose and outcome following OHCA.
Get that AED out! The Circadian Dilemma of Public Access Defibrillation
Using cardiac arrest registries for clinical trials by adding wagons to a rolling train
Implications of an Individualized Resuscitation Strategy Using Continuous Rhythm and Physiologic Status Assessment During Ongoing CPR
Prior studies have proposed defibrillator biosignal algorithms which characterize cardiac arrest rhythm and physiologic status. We evaluated whether a novel, individualized resuscitation strategy that integrates multiple ECG and impedance-based algorithms could reduce CPR interruptions and better align rescuer actions with patient-specific physiology.
Patient cohorts of interest in resuscitation science - Aligning Cardiac Arrest Registry Outputs with Stakeholder Needs
Cardiac arrest registries can benchmark, enhance quality of care and provide data for research. Key stakeholders from Emergency Medical Communication Centre (EMCC), Emergency Medical Services (EMS), In-Hospital Care Providers (IHCP) and Recovery and Rehabilitation Providers (RRP) have different perspectives, and registry results and patient cohorts should be tailored to facilitate benchmarking, quality improvement projects and research in all sections of the chain of survival. In this paper, we describe different cohorts of interest, exemplified by data from the Norwegian Cardiac Arrest Registry (NorCAR).
Cardiac arrest after hanging: a scoping review
Hanging is a common cause of suicide and asphyxial cardiac arrest. There are few data to inform the treatment of cardiac arrest after hanging. We designed a scoping review to describe evidence relating to interventions and outcomes in patients with and without cardiac arrest after hanging.
The Role of Hospital Performance on Race and Ethnicity Outcome Disparities for US Non-Traumatic Out-of-Hospital Cardiac Arrests
Factors contributing to worse outcomes for out-of-hospital cardiac arrests (OHCA) from minoritized communities are poorly understood. We sought to evaluate the impact of receiving hospital performance on OHCA outcome disparities.
E-CPR: Does ECMO enhance or relieve the pressure on the injured heart?
Unraveling some of the myth about drowning, out-of-hospital cardiac arrest and outcomes: Many critical factors and processes, most of them disappointingly difficult to manage
The Role of Amiodarone in Out-of-Hospital Cardiac Arrest Resuscitation: The AMIODAWHY Study
Initial oxygen centration for preterm infants in the delivery room resuscitation: Is it the time to modify current recommendations?
Defining a core outcome comparator for patients treated with extracorporeal cardiopulmonary resuscitation
The impact of pediatric post-cardiac arrest care on survival: A multicenter review from the AHA get with the Guidelines®-resuscitation post-cardiac arrest care registry
Adherence to post-cardiac arrest care (PCAC) recommendations is associated with improved outcomes for adults. We aimed to describe the survival impact of meeting American Heart Association (AHA) PCAC guidelines in children after cardiac arrest.