Use of Anti-PD1 Blockade After Hedgehog Inhibitors or as First-Line Therapy for Gorlin Syndrome
Psoriasis Risk With Immune Checkpoint Inhibitors
Immune checkpoint inhibitors (ICIs) are recognized as revolutionary cancer therapies but have raised concerns about immune-related adverse events, including the development of autoimmune diseases.
Long-Term Risk of Autoimmune and Autoinflammatory Connective Tissue Disorders Following COVID-19
Few studies have investigated the association between COVID-19 and autoimmune and autoinflammatory connective tissue disorders; however, research with long-term observation remains insufficient.
Skin Cancer Diagnosis by Lesion, Physician, and Examination Type: A Systematic Review and Meta-Analysis
Skin cancer is the most common cancer in the US; accurate detection can minimize morbidity and mortality.
Spesolimab Response in a Patient With Steroid-Resistant Sweet Syndrome
Doxycycline Postexposure Prophylaxis (DoxyPEP) for Bacterial STI Prevention
Low-Dose Oral Minoxidil Initiation for Patients With Hair Loss: An International Modified Delphi Consensus Statement
The results of small studies suggest that off-label use of low-dose oral minoxidil (LDOM) may be safe and effective for patients with hair loss, but larger trials and standardized guidelines are lacking.
Skin Inflammation, Systemic Inflammation, and Cardiovascular Disease in Psoriasis
Psoriasis is associated with increased cardiovascular risk, but the underlying pathogenic mechanisms remain unclear. Elucidating these mechanisms can help develop treatment strategies and enhance understanding of the link between peripheral inflammation, such as psoriatic skin lesions, and cardiovascular disease (CVD).
Wound Characteristics Among Patients Exposed to Xylazine
The alpha-2 agonist xylazine is increasingly detected as an adulterant in illicitly manufactured fentanyl. There is concern that xylazine may be responsible for an emerging pattern of necrotizing wounds among people who use drugs, but the clinical features of wounds associated with xylazine remain poorly characterized.
Psychometric Properties and Meaningful Change Thresholds of the Vitiligo Area Scoring Index
Defining meaningful improvement using the Total Vitiligo Area Scoring Index (T-VASI) and the Facial VASI (F-VASI) aids interpretation of findings from clinical trials evaluating vitiligo treatments; however, clear and clinically meaningful thresholds have not yet been established.
Successful Treatment of Recalcitrant Chloracne With Adalimumab in an Older Man
Impact of Clinical Information on Melanocytic Skin Lesion Pathology Diagnosis: A Scoping Review
There is poor accuracy and reproducibility for the histopathologic diagnosis of melanocytic skin lesions, and the provision of clinical information may improve this.