Archives of Rheumatology

Regional variations in psoriatic arthritis: Insights from a nationwide multicenter analysis in Türkiye
Kılıç E, Kılıç G, Tekeoğlu İ, Sargın B, Acer Kasman S, Alkan H, Şahin N, Cengiz G, Cüzdan N, Albayrak Gezer İ, Keskin D, Mülkoğlu C, Reşorlu H, Sunar İ, Bal A, Duruöz MT, Küçükakkaş O, Yurdakul OV, Alkan Melikoğlu M, Aydın Y, Ayhan FF, Bodur H, Çalış M, Çapkın E, Devrimsel G, Orhan K, Hizmetli S, Kamanlı A, Keskin Y, Ecesoy H, Kutluk Ö, Şen N, Faruk Şendur Ö, Tolu S, Toprak M, Tuncer T and Nas K
The study aimed to investigate and compare clinical features, disease activity, and the overall disease burden among psoriatic arthritis (PsA) patients across seven distinct geographic regions in Türkiye.
Could rituximab be a silver lining in refractory bone marrow fibrosis caused by lupus?
Bulut Gökten D, Yümün Kavak F and Mercan R
Gout and erectile dysfunction: Increased carotid intima-media thickness is independently associated with greater likelihood for erectile dysfunction
Yigit E, Yasar S, Can M and Bayraktar Z
The study aimed to compare gout patients and healthy subjects in terms of erectile dysfunction, carotid intima-media thickness (CIMT), and other variables and to investigate the relationship between CIMT and erectile dysfunction.
Proprotein convertase subtilisin/kexin type 9 and apelin in fibromyalgia syndrome
Pihtili Taş N, Aydogan Baykara R, Kamanli A, Gürbüz A, Cure E, Cumhur Cüre M, Erdem M and Tasar Yildirim T
This study aimed to investigate the potential roles of proprotein convertase subtilisin/ kexin type 9 (PCSK9) and apelin in the etiology of fibromyalgia syndrome (FS).
Novel use of interleukin-1 antagonists in male familial Mediterranean fever patients with infertility: Case series
Egeli B, Parlar K, Filiz B, Durucan I and Ugurlu S
Prevalence and characteristics of bronchiectasis in ANCA-associated vasculitis: A systematic review and meta-analysis
Gu Y, Zhang T, Zhu W, Han Y and Shi J
This systematic review and meta-analysis aimed to investigate the prevalence of bronchiectasis (BR) in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), the association of BR with manifestations of AAV, and the features of BR in AAV.
Osteoporosis knowledge and awareness among rheumatoid arthritis patients: A cross-sectional controlled study
Tomay Aksoy Ö, Kutluk Ö and Sezer İ
The aim of this study was to investigate the levels of knowledge and awareness of osteoporosis (OP) in patients with rheumatoid arthritis (RA).
Association of focus score and extraglandular involvement in Sjögren's syndrome: A study on antinuclear antibodies and minor salivary gland pathology
Ergün MÇ, Yılmaz O, Bilgen H, Oltulu P, Kılınç F and Tunç R
This study aimed to investigate the relationship between patients with and without extraglandular involvement in Sjögren's syndrome (SS) by analyzing ANA (antinuclear antibody) and ENA (extractable nuclear antigen) results and minor salivary gland pathology findings.
Sixth cranial nerve palsy in giant cell arteritis: A systematic review
Sawada H, Nishimura Y and Tamaki H
This study aimed to review and describe isolated sixth cranial nerve or abducens nerve palsy that may present with subtle ophthalmoplegia in patients with giant cell arteritis (GCA).
The hidden oncological challenge in Sjögren's syndrome with a focus on pharyngeal cancer
Yoo WH, Min Kim K and Choi Y
Difficult-to-treat axial spondyloarthritis patients
Saygın Öğüt T, Erbasan F, Şahiner MF, Nokay M, Yörük Öğüt A, Dilbil M, Terzioğlu ME and Yazısız V
This study aimed to formulate D2T (difficult to treat) criteria for axial spondyloarthritis (AxSpA) patients and identify the prevalence of D2T patients and their characteristics.
Acquired Madelung's deformity as a cause of recurrent monoarthritis in a young patient
El Hasbani G, Jawad A and Uthman I
Validity and reliability of the Turkish version of Exercise Benefits/ Barriers Scale: Perceived exercise benefits and barriers of patients with different axial spondyloarthritis subtypes
Sarac DC, Durak Ediboglu E, Ozer Kaya D, Duran G, Akatay EA, Gucenmez S, Akar S and Bayraktar D
The aim of this study was to translate the Exercise Benefits/Barriers Scale (EBBS) into Turkish and investigate the perceptions of Turkish-speaking patients with different axial spondyloarthritis (axSpA) subtypes regarding exercise benefits and barriers.
The impact of ex vivo ozone injection into the synovial fluid in patients with knee osteoarthritis: A controlled clinical trial
Ata E, Özgüç S, Temel MH, Beyaztaş H, Aktaş S and Güler EM
This study aimed to examine the effect of varying ozone doses on proinflammatory cytokine levels in the synovial fluid collected from individuals with knee osteoarthritis.
Comparison of creatine kinase elevation caused by Janus kinase inhibitors and interleukin-6 inhibitors in patients with rheumatoid arthritis: A propensity score-matched study
Tada M, Okano T, Mamaoto K, Yamada Y, Orita K, Mandai K, Anno S, Iida T, Inui K and Koike T
This study aimed to examine whether creatine kinase (CK) elevation occurs with interleukin (IL)-6 inhibitors, as in Janus kinase (JAK) inhibitors, which are reported to increase CK levels in rheumatoid arthritis.
New and future perspectives in familial Mediterranean fever and other autoinflammatory diseases
Çam V, Ercan Emreol H and Ozen S
Systemic autoinflammatory diseases are a group of disorders characterized by sterile episodes of inflammation resulting from defects in the innate immune system. In contrast to classical autoimmune diseases, where circulating autoantibodies and the adaptive immune system are involved, these conditions involve excessive presence of proinflammatory cytokines leading to inflammatory attacks. Excessive cytokine production, functional mutations in regulatory pathways, excessive interferon production, defects in the nuclear factor-kappa B signaling pathway, abnorARCHmal protein folding, and complement activation are the mechanisms leading to autoinflammatory diseases. A defect in the mTOR pathway and trained immunity are newly discovered possible causes in pathogenesis. Early onset and severe forms of classical rheumatological diseases have been more frequently associated with autoinflammatory diseases in the last decade. Therefore, monogenic autoinflammatory diseases should be considered in rheumatic diseases with family history, consanguinity, early onset, and severe disease. The combination of functional and genotyping research will help to identify unclassified patients. The optimal treatment strategy remains uncertain, functional studies such as interferon signature and cytokine profiling, may prove valuable in guiding the treatment process. Stem cell transplantation strategies in autoinflammatory diseases with partial response to biological therapies can be considered. Autoinflammatory diseases are becoming increasingly complex and are bringing new perspectives to already known rheumatic diseases. Although we have effective treatments, we are still far from personalized recommendations.
Can serum granulocyte-macrophage colony-stimulating factor and CCL17 levels be a marker of disease activation in spondyloarthritis?
Koçak Ulucaköy R, Kılıç A, Batıbay S, Çobanoğlu İM, Yıldırım Öztürk EN, Günendi Z, Sepici Dinçel A and Göğüş FN
The aim of this cross-sectional study was to investigate if serum levels of granulocytemacrophage colony-stimulating factor (GM-CSF) and CC chemokine ligand 17 (CCL17) correlate with disease activity in axial spondyloarthritis (axSpA) and peripheral spondyloarthritis (pSpA) patients.
Neuropathic component of chronic musculoskeletal pain in patients with post-COVID-19: A cross-sectional study
Gümüş Atalay S, Borman P, Yaman A and Yaşar E
This study aimed to evaluate the neuropathic component of chronic musculoskeletal pain in post-coronavirus disease 2019 (COVID-19) and examine the relationship between neuropathic pain and clinical and demographic characteristics.
Is the development of arrhythmia predictable in rheumatoid arthritis?
Gülkesen A, Yıldırım Uslu E, Akgöl G, Alkan G, Kobat MA, Gelen MA and Uslu MF
This study aimed to determine whether there is a difference in the electrocardiography (ECG) measurements of healthy controls and rheumatoid arthritis (RA) patients and to predict whether they can be used to determine the risk of arrhythmia in patients.
Prevalence and characteristics of juvenile fibromyalgia syndrome in pediatric rheumatic diseases: A comparative study
Özomay Baykal G, Kurtuluş D, Ata S and Sözeri B
The study aimed to evaluate the frequency of juvenile fibromyalgia syndrome (JFMS) in patients diagnosed with juvenile idiopathic arthritis (JIA) and familial Mediterranean fever (FMF) with joint symptoms and compare them with a healthy control group.
Assessment of electronic health literacy and its association with self-management among gout patients: A cross-sectional study
Qian J, Yao X and Liu T
This study aimed to assess electronic health (eHealth) literacy and self-management ability among gout patients in China and analyze their correlation.