We present the comparative study of the analytical forward model and the statistical simulation of the Compton single scatter in the Positron Emission Tomography. The formula of the forward model has been obtained using the Single Scatter Simulation approximation under simplified assumptions and therefore we calculate scatter projections using independent Monte Carlo simulation mimicking the scatter physics. The numerical comparative study has been performed using a digital cylindrical phantom filled in with water and containing spherical sources of emission activity located at the central and several displaced positions. Good fits of the formula-based and statistically generated profiles of scatter projections are observed in the presented numerical results.

Three methods for the estimation of blood or breath alcohol concentration (BAC/BrAC) from biosensor measured transdermal alcohol concentration (TAC) are evaluated and compared. Specifically, we consider a system identification/quasi-blind deconvolution scheme based on a distributed parameter model with unbounded input and output for ethanol transport in the skin and compare it to two more conventional system identification and filtering/deconvolution techniques for ill-posed inverse problems, one based on frequency domain methods, and the other on a time series approach using an ARMA input/output model. Our basis for comparison are five statistical measures of interest to alcohol researchers and clinicians: peak BAC/BrAC, time of peak BAC/BrAC, the ascending and descending slopes of the BAC/BrAC curve, and the area underneath the BAC/BrAC curve.