Evolution of Well-Being and Associated Factors during the COVID-19 Pandemic
The COVID-19 pandemic was a global public health crisis with an unparalleled impact worldwide, presenting a significant challenge for both physical and mental health. The main objective of this study was to analyze the risk of depression during the COVID-19 pandemic and how this was affected by sociodemographic factors, pandemic fatigue, risk perception, trust in institutions, and perceived self-efficacy.
Clinical Significance of Serum MMP-9, S100-β and GFAP in Patients with Mental Disorders after Traumatic Brain Injury
Diagnosing psychiatric disorders following craniocerebral trauma primarily depends on clinical symptoms and neuropsychological evaluation, which can be subjective and limited. This study aimed to investigate the diagnostic value of serum matrix metalloproteinase-9 (MMP-9), S100 calcium-binding protein β (S100-β), and glial fibrillary acidic protein (GFAP) in post-traumatic mental disorders.
Alcohol Use Disorders and Suicidal Behaviour: A Narrative Review
Alcohol Use Disorders (AUD), affective disorders, and personality disorders are among the most prevalent mental health conditions observed in individuals exhibiting suicidal behavior, encompassing both completed and attempted suicides. A robust association between AUD and suicidal behavior has been established through retrospective and prospective cohort studies. Research on the relationship between alcohol consumption and self-harm has predominantly focused on Western and high-income countries, whereas approximately one-third of the global population, including half of the world's countries, lacks accessible suicide data. This study aims to present an updated review of empirical evidence regarding the risk of suicide associated with AUD in both developed and developing nations.
Potential Biomarkers and Treatment of Neuroinflammation in Parkinson's Disease
Parkinson's disease (PD) is a degenerative disease of the central nervous system primarily affecting middle-aged and elderly individuals, significantly compromising their quality of life. Neuroinflammation is now recognized as a key feature in the pathogenesis of PD. This study reviews recent advances in the identification of potential biomarkers associated with neuroinflammation in PD and their significance for therapeutic strategies. These findings suggest that inflammatory factors play a pivotal role in PD treatment, and interventions involving anti-inflammatory drugs, physical exercise, and dietary modifications have shown promising results in mitigating disease progression.
Exploring the Influence of Career Decision Self-Efficacy on Adjustment Challenges in Psychiatric Nursing Students: A Cross-Sectional Insight
To explore the relationship between Career Decision-Making Self-Efficacy and maladjustment among psychiatric nursing students.
The Significance of Psychological Support in Managing Depression in Parkinson's Disease: Combining Venlafaxine with Pramipexole and Psychological Care
Depression is a common comorbidity in patients with Parkinson's disease (PD) and can significantly impact their overall well-being. The combination of venlafaxine and pramipexole is a standard treatment approach for depression in PD. However, the effects of incorporating psychological care into the treatment regimen remain unclear. This study aimed to investigate the impact of psychological intervention in the treatment of depression in Parkinson's disease, using a combination of venlafaxine and pramipexole.
A Multi-Label Deep Learning Model for Detailed Classification of Alzheimer's Disease
Accurate diagnosis and classification of Alzheimer's disease (AD) are crucial for effective treatment and management. Traditional diagnostic models, largely based on binary classification systems, fail to adequately capture the complexities and variations across different stages and subtypes of AD, limiting their clinical utility.
Interdisciplinary Approaches in Psychiatric Research: From Neural Dynamics to Clinical Applications in Schizophrenia
This editorial explores the dynamic psychiatric research field by focusing on interdisciplinary approaches to understand the complexity of mental disorders by placing particular emphasis on schizophrenia. It highlights the need to integrate findings from diverse scientific disciplines, such as neuroscience, computational modeling and genomics, to unravel the multifaceted nature of these conditions. The potential of interdisciplinary research to transform our knowledge and the treatment of psychiatric disorders is underscored by moving beyond traditional models and developing more nuanced frameworks to more effectively address these complexities. Thus by combining perspectives from different fields, significant advancements are expected in the diagnosis, treatment and prevention of mental disorders like schizophrenia, and will open new research and clinical practice avenues in psychiatry.
Psychological Status and its Influencing Factors of Staff in a District of Shenzhen: A Retrospective Study
Anxiety, depression, and sleep disorders, as psychological and emotional diseases, have serious impact on people's physical and mental health, and receive increasing academic attention. This study aimed to examine anxiety, depression, and sleep disorder of staff in a district of Shenzhen and to provide the basis for the development of targeted intervention measures to improve the psychological status of cadres.
Mobile Health for Obsessive-Compulsive Disorder: Patients' Preferences and Perception of Patient-Centeredness
The increasingly fast development of mobile health technologies holds significant value for individuals dealing with mental health conditions. However, inadequate consideration of patients' preferences and expectations undermines real-world outcomes, including sustained adherence. Driven by the belief that specific characteristics, such as youth and higher education, of individuals with obsessive-compulsive disorder make them suitable for digital adoption, we investigated mHealth-related desirability factors within this patient group.
Impact of Emergency Warning Nursing on CRP, PCT, TNF-α and Clinical Indicators in Patients with Acute Stress Disorder under Hierarchical Analysis
In emergency warning nursing, the pre-alert system significantly influences the biochemical markers and clinical outcomes of patients with Acute Stress Disorder. Therefore, this study applies hierarchical analysis to explore the impact of early warning nursing on crucial indicators such as C-reactive protein (CRP), procalcitonin (PCT), tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), and assess their clinical efficacy.
Repetitive Transcranial Magnetic Stimulation Combined with Ginkgo Diterpene Lactone Meglumine Injection Recover Cognitive and Neurological Functions of Patients with Acute Ischemic Stroke
Acute ischemic stroke (AIS) is a prevalent and challenging neurological condition associated with high mortality and morbidity rates. This study aimed to evaluate the therapeutic efficacy of repetitive transcranial magnetic stimulation (rTMS) combined with ginkgo diterpene lactone meglumine injection (GDLMI) on cognitive and neurological function recovery in patients with AIS.
The Role of Mindfulness Decompression Therapy in Managing Acute Stress Disorder in Traumatic Fracture Patients
Traumatic fractures are common orthopedic injuries with higher incidence globally, leading to acute stress disorder (ASD). Therefore, this study aimed to analyze the clinical outcomes of mindfulness-based stress reduction (MBSR) therapy in patients with traumatic bone fractures suffering from ASD.
Disgust and Other Negative Emotions in the Relationship between Mental Contamination and Post-Traumatic Stress Disorder: A Systematic Review
Mental contamination (MC) refers to feelings of internal filthiness associated with contamination obsessions. Ego-dystonic memories and thoughts can trigger MC, although it can also be activated by trauma, which is associated with the onset of post-traumatic stress disorder (PTSD). Research shows that MC, negative emotions and PTSD can occur simultaneously. Despite considerable interest from researchers and clinicians, to the best of our knowledge, no systematic review has been carried out on the relationship between disgust and other negative emotions with MC and PTSD. Therefore, we conducted this systematic review to summarise and synthesise the current understanding of these constructs in PTSD. The main objective of this study was to review the association between MC, post-traumatic stress disorder and trauma; the role of disgust and other negative emotions in these associations; and whether the relationship between MC and trauma is limited to traumatic sexual experiences.
Ginsenoside Rg1 Promotes the Survival, Proliferation, and Differentiation of Senescent Neural Stem Cells Induced by D-galactose
Neural stem cells (NSCs) disrupt with aging, contributing to neurodegeneration. Ginsenoside Rg1 (Rg1), a compound found in Ginseng, is known for its anti-aging effects; however, its role in the progression of aging NSCs remains unclear. Therefore, this investigation explored the impact of Rg1 on the growth and maturation of aging NSC and elucidated its underlying molecular mechanisms.
Expanding the Role of Mindfulness in IBD Care: Bridging Psychological Well-being and Disease Management
No abstract present.
Development and Psychometric Validation of the Cyber-Self Scale (CSS) in Saudi Arabia
Measuring adolescents' and youths' perception of their Cyber-Self can enhance the understanding of how digital technology influences identity formation. While psychological literature offers numerous measures of the self, there is a notable lack of studies addressing the measurement of the Cyber-Self. This study aims to evaluate the reliability, factorial- and criterion-related validity, and measurement invariance of the Cyber-Self Scale (CSS) across age and gender among the youth and adolescents in Saudi Arabia.
Current Status of Depression in Patients with Endometriosis and Rheumatoid Arthritis
Endometriosis often causes chronic pain and fertility issues, exacerbating the risk of depression and complicating conditions like rheumatoid arthritis, which further impacts quality of life. This study aimed to explore the detection rate of depression in patients with endometriosis and rheumatoid arthritis by using different diagnostic criteria, and to analyze the occurrence and influencing factors.
How Do Psychiatry Residents View Their Training in Spain? A Mixed-Method Survey
Efforts to improve psychiatry training must incorporate residents' assessment of their training. This study sought to collect the opinion of residents about the program that has been in force in Spain since 2008, until the current transition to a new plan.
Psychological Intervention for Depression and Anxiety in Hemodialysis Patients: A Meta-Analysis
With the advancement of blood purification technology, there is increasing attention to the mental health of hemodialysis patients, particularly concerning depression. This study aims to determine the effect of psychological interventions on anxiety and depression in hemodialysis patients through a meta-analysis.
Cross-Sectional Study on Analysis of the Prevalence and Influencing Factors of Sleep Disorders among College Students in a Certain University in China
Maintaining good sleep quality is crucial for improving the efficiency of college students. Therefore, this cross-sectional study aims to elucidate the prevalence of sleep disorders among students and analyze its risk factors.